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Dean's List: New Funding Awards

Notable & novel scientific awards to celebrate. 

2023: January, February, March, April, May, June, July, August, September, October, November, December
 

December 2023

New Federal Awards:
     
Sanjana Dayal Internal Medicine NIH RO1
4 years
Preventive mechanisms of Age-associated Thrombosis
John Fingert, Contact PI
Todd Scheetz, MPI
Budd Tucker, MPI
Ophthalmology NIH R21
2 years
Stem cell approaches to normal tension glaucoma
Robert Piper, Contact PI
Chris Anern, MPI
Physiology NIH R33
2 years
Towards systematic analysis of cardiac voltage-gated sodium channel beta subunit Function
Eric Taylor Physiology NIH R01
4 years
Regulation of Hepatic Fuel Fluxes by the Mitochondrial Dicarboxylate Carrier
Mary Weber Microbiology NIH R61
3 years
Development of genetic tools for overexpression and targeted mutagenesis of Orientia tsutsugamushi TPR proteins

 

Competitive Awards:
     
Enrique Leira Neurology NIH U24
5 years
The University of Iowa's Regional Stroke Research Network

Other Awards:
     
Stephanie Chen Pathology Exact Sciences Corporation
3 years
Specimen Collection Study to Evaluate Biomarkers in Subjects with Cancer
Nabeel Hamzeh Internal Medicine Bristol-Myers Squibb Company
3 years
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the  Efficacy, Safety, and Tolerability of BMS-986278 in Participants with Idiopathic Pulmonary Fibrosis
Markus Kuehn Ophthamology Animal Eye Consultants of Iowa
2 years
Adaptive Immune Responses Contributing to Canine Glaucoma
Delwyn Miller Psychiatry University of Southern California
5 years
Alzheimer's Disease Neuroimaging Initiative (ADNI4)
Amy Ryan Anatomy and Cell Biology Children's Hospital of Los Angeles
1 year
Development of a model that integrates inflammation and tissue injury to predict and mitigate the post-acute sequelae of COVID-19
Michael willey Orthopedics MEND Nutrition, Inc.
3 years
MENDTM Clinical Trial Proposal

 

November 2023

New Federal Awards:
   

Top of Page

 

 

 

Yi Huang Internal Medicine NIH R01
3 years
Role of LSD1 in Triple Negative Breast Cancer Development and Therapeutic Response

 

Competitive Awards:
     
Stanley Perlman Microbiology NIH R01
5 years
Role of LSD1 in Triple Negative Breast Cancer Development and Therapeutic Response

 

Other Awards:
     
Umar Farooq Internal Medicine Cargo Therapeutics
5 years
An Open-label, Multicenter Phase 2 Study Evaluating the Efficacy and Safety of CRG-022, a CD22-Directed Autologous Chimeric Antigen Receptor (CAR) T-cell Therapy in Participants With Relapsed/Refractory Large B-Cell Lymphoma After CD19-Directed CART-cell
Umar Farooq Internal Medicine Janssen Research & Development, Inc.
4 years
A Phase 1b Multicenter, Open-label, Study of JNJ-90009530, an Autologous Anti-CD20 CAR-T Cell Therapy in Adult Participants with Relapsed or Refractory B-cell Non- Hodgkin Lymphoma
Philip Gander, Contact PI
Joel Berger MPI
Radiology, Neurosurgery

REAM Foundation,
2 years

Novel Investigation of Brain Mechanisms for Different Triggers in Misophonia
Dilek Ince Internal Medicine Corixa Corporation
3 years
A Phase 2b, randomized, controlled, open-label study to evaluate the immune response and safety of the RSVPreF3 OA investigational vaccine in adults (50 years of age) when administered to lung and renal transplant recipients comparing 1 versus 2 doses an
Annie Killoran Nurology Genetech, Inc.
3 years
A Phase II, Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study To Evaluate The Safety, Biomarkers, And Efficacy Of Tominersen In Individuals With Prodromal And Early Manifest Huntington's Disease
Douglas Laux Internal Medicine Replimune, Ltd.
3 years
A Phase 2, Open-label, Multicenter Study Investigating RP3 in Combination with Other Therapy in Patients with Locoregionally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck
Douglas Laux Internal Medicine Seagen, Inc.
3 years
A phase 1 study of SGN-BB228 in advanced melanoma and other solid tumors
Mohammed Milhem Internal Medicine Seagen, Inc.
3 years
A phase 1 study of SGN-BB228 in advanced melanoma and other solid tumors
Sneha Phadke Internal Medicine AstraZeneca Pharmaceuticals LP
3 years
A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/
Chen Tan Internal Medicine Ansun Biopharma, Inc.
3 years
A Phase III Randomized Placebo-Controlled Study to Examine  the Efficacy and Safety of DAS 181 for the Treatment of Lower Respiratory Tract  Parain:fluenza Infection in Immunocompromised Subjects
Yousef Zakharia Internal Medicine Worldwide Clinical Trials, Inc.
3 years
A PHASE 1B/2 BASKET STUDY OF ACR-368 AS MONOTHERAPY AND IN COMBINATION WITH GEMCITABINE IN ADULT SUBJECTS WITH PLATINUM -RESISTANT OVARIAN CARCINOMA, ENDOMETRIAL ADENOCARCINOMA, AND UROTHELIAL CARCINOMA BASED ON ACRIVON ONCOSIGNATURE STATUS

 

October 2023

New Federal Awards:
    Top of Page
James Byrne Radiation Oncology NIH K08
5 years
Exploiting Carbon Monoxide Biofoams to Radio-Sensitize Rectal Cancer Cells While Protecting Normal Bowel
Grace Ciampa Internal Medicine NIH F31
2 years
Examining the Function of a Novel Protein in the Cardiac Junctional Membrane Complex

 

Competitive Awards:
     
Thomas Scholz Pediatrics Iowa Department of Human Services 
1 year
MHDS 24-008 Community Circle of Care
Kirill Nourski Neurosurgery University of Wisconsin-Madison 
4 years
Mechanisms of  Loss, Recovery and Disorders of Consciousness

 

Other Awards:
     
Ernesto Ruiz Duque Internal Medicine Bristol-Myers Squibb Company
3 years
DISCOVER-HCM
Rami El Abiad Internal Medicine

Celldex Therapeutics, Inc.

3 years

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Barzolvolimab (CDX-0159) in Adults with Active Eosinophilic Esophagitis
Andrew Russo Molecular Physics & Biophysicis Seattle Institute for Biomedical and Clinical Research
5 years
Role of Sleep Disruption after mTBI as a Driver of Chronic Post-Traumatic Headache
Alejandro Comellas Freymond Internal Medicine IQVIA RDS Inc.
​3 years
A Phase 3, 52-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm  Efficacy and Safety Study with Open-Label Extension of BLU-5937 in Adult Participants with Refractory  Chronic Cough, Including Unexplained Chronic Cough (CALM-1)
Muhammad Furqan Internal Medicine AbbVie, Inc.
3 years
A Phase 1 first-in-human study evaluating safety, pharmacokinetics and efficacy of ABBV-706 as monotherapy and in combination with budigalimab (ABBV-181), carboplatin, or cisplatin in adult subjects with advanced solid tumors.
Muhammad Furqan Internal Medicine BeiGene USA
3 years
A Phase 1a/1b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-A3055, Alone and in Combination With Tislelizumab in Patients With Selected Advanced or Metastatic Solid Tumors
Muhammad Furqan Internal Medicine Poseida Therapeutics, Inc.
3 years
A PHASE 1 DOSE ESCALATION AND EXPANDED COHORT STUDY OF P-MUC1C-ALLO1 IN ADULT SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS
David Axelrod Surgery CTI Clinical Trial Services, Inc.
3 years
An open-label, controlled, randomized Phase 3 trial evaluating 12-month kidney function in highly sensitized (cPRA 99.9%) kidney transplant patients with positive crossmatch against a deceased donor, comparing desensitization using imlifidase with standa
Sneha Phadke Internal Medicine NSABP Foundation, Inc.
5 years
CAMBRIA-1: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy with Camizestrant (AZD9833, a Next Generation, Oral Selective Estrogen Receptor Degrader) versus Standard Endocrine Therapy (Aromatase Inhibitor or
Carla Nester Pediatrics Apellis Pharmaceuticals, Inc.
3 years
AN OPEN-LABEL, NONRANDOMIZED, MULTICENTER EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF PEGCETACOPLAN IN PARTICIPANTS WITH C3 GLOMERULOPATHY OR IMMUNE-COMPLEX MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS
Patrick Sinn Pediatrics Cystic Fibrosis Foundation
2 years
005661G223 Base-Editing for Life-Long Correction of CF Airways
Vishnu Mani Surgery Direct Biologics, LLC
3 years
Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles for Hospitalized  Patients with Moderate-to-Severe ARDS: A Phase III Clinical Trial
Eric Hoffman Radiology Imperial College London
2 years
THE BLF EARLY COPD DEVELOPMENT PARTNERSHIP GRANT
Brian Link Internal Medicine Mayo Clinic
3 years
Characteristics and outcomes of patients with Diffuse Large B-cell Lymphoma Receiving Frontline Treatment at Cancer Centers within the LEO Cohort, ML43785

 

September 2023

New Federal Awards:
    Top of Page
John Fingert, Contact PI
Todd Scheetz, MPI
Ophthalmology NIH R01
5 years
Genetic Factors for Glaucoma in the OHTS; Risk, Progression and Mechanism
Aloysius Klingelhutz Microbiology NIH R21
2 years
The role of ISG15 and ISGylation in the senescence-associated secretory phenotype
Elizabeth Newell Pediatrics NIH R01
5 years
Mechanisms of type I interferon neuropathology following traumatic brain injury
Jon Houtman Microbiology NIH R25
5 years
R25 YES: Cancer Research Opportunities at Iowa

 

Competitive Awards:
     
Milan Sonka, Contact PI
John Buatti, MPI
Radiation Oncology NIH R56
1 year
Deep LOGISMOS
Vincent Magnotta, Contact PI
John Wemmie, MPI
Radiology,
Psychiatry
NIH R01
5 years
Cerebellar metabolism, neural circuits, and symptoms in bipolar disorder

 

Other Awards:
     
Umar Farooq Internal Medicine Angiocrine Bioscience, Inc.
3 years
Angiocrine Long Term Follow-Up Umbrella Study
Umar Farooq Internal Medicine Nektar Therapeutics
3 years
A PHASE 2/3, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF NKTR-255 VS PLACEBO FOLLOWING CD19-DIRECTED CAR-T CELL THERAPY IN PATIENTS WITH RELAPSED/REFRACTORY LARGE B-CELL LYMPHOMA
Bruce Gantz Otolaryngology Cochlear Americas
3 years
Preliminary Evaluation of a Dexamethasone Eluting Electrode Array
Marlan Hansen Otolaryngology Julius Clinical Research B.V.
3 years
A Natural History Study in Individuals with Otoferlin Gene  (OTOF)-Mediated Hearing Loss
Annie Killoran Neurology Worldwide Clinical Trials, Inc.
3 years
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in Subjects With Parkinson's Disease With a Pathogenic Variant in the Glucocerebrosidase (G
Antonio Sanchez Internal Medicine Merck Sharp & Dohme LLC
3 years
A Phase 2b Randomized, Double-Blind Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Efinopegdutide (MK-6024) in Adults with Precirrhotic Nonalcoholic Steatohepatitis
Antonio Sanchez Internal Medicine PPD Investigator Services, LLC
3 years
A Phase 3, Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Fazirsiran in Participants With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease
Christopher Strouse Internal Medicine Poseida Therapeutics, Inc.
3 years
Open-Label, Multicenter, Phase 1 Study to Assess the Safety of P-BCMA-ALLO1 in Subjects with Relapsed / Refractory Multiple Myeloma (MM)

August 2023

New Federal Award:
    Top of Page
Alexander Boyden Pathology NIH R01
5 years
Pathogenic B cell:CD4 T cell interactions in a novel B cell-dependent EAE mouse model of multiple sclerosis
Sean Fain Radiology NIH R01
5 years
Dynamic Imaging of Lung Ventilation and Perfusion Using CT and MRI
Gena Ghearing Neurology CDC
5 years
Expanding epilepsy self-management support in healthcare networks (EXPAND)
Aleksander Lenert Internal Medicine

NIH K23
3 years

Investigating Disease Activity, Bone Damage and Interleukin-1 Genes in Adult SAPHO Syndrome and Chronic Nonbacterial Osteomyelitis 
Yi Luo Urology DOD, CDMRP
4 years
CP220038 - Development of a novel DNA aptamer-based IFN-y targeted therapy for chronic cystitis pain
Wendy Maury, Contact PI
Noah Butler, MPI
Microbiology NIH UH2
2 years
Defining the effect of Plasmodium infection on Ebola virus vaccine efficacy
Ben Miskle Pharmacy Practice and Science (Award in Psychiatry) SAMHSA H79
5 years
Iowa Naloxone Expansion and Training (IA-NEXT)
Catherina Pinnaro Pediatrics NIH K23
3 years
Hyperglycemia in Turner syndrome: Mechanisms and X chromosome contributions
Matthew Potthoff Neuroscience & Pharmacology NIH R01
5 years
Therapeutic Potential of FGF21 for Alzheimer's Disease 
Brett Faine, Contact PI
David Talan, MPI
Emergency Medicine NIH R21
2 years
Personalized Antibiotic Therapy in the Emergency Department: PANTHER Trial
Seth Tomchik Neuroscience & Pharmacology NIH R01
2 years
Dopaminergic circuit modulation of learning and arousal-mediated memory enhancement
Elliott Sohn, Contact PI
Jon Houtman, MPI
Milan Sonka, MPI
Ophthalmology,
Microbiology,
Electrical & Computer Engineering
NIH R01
4 years
MMP-9 based immune-driven mechanisms of neovascular AMD

 

Competitive Awards:
     
Marlan Hansen, Contact PI
C. Guymon, MPI
Otolaryngology NIH R01
5 years
Reduction of Intracochlear Trauma and Fibrosis Using Dual Network, Zwitterionic Hydrogel Thin Films on Cochlear Implant Surfaces
Robert Mullins, Contact PI
Budd Tucker, MPI
Ophthlamology NIH R01
4 years
Choriocapillaris Protection and Replacement in AMD

 

Other Awards:
     
David Bender OBGyn GOG Foundation
3 years
Randomized, multicenter, open-label, phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FR-positive recurrent platinum-sensitive epithelial ovarian, fallopian tube,
James Byrne Radiation Oncology V Foundation for Cancer Research
3 years
Overcoming immunotherapy resistance using oxygen-entrapping materials
Marcelo Correia Internal Medicine Lilly USA, LLC
3 years
A Phase 3, Open-Label Study of Once Daily LY3502970 Compared with Insulin Glargine in Adult Participants with Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)
Umar Farooq Internal Medicine ImmPACT Bio USA Inc.
3 years
A PHASE 1/2 MULTI-CENTER STUDY EVALUATING THE SAFETY AND EFFICACY OF IMPT-314, A CD19/20 BISPECIFIC CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY IN PARTICIPANTS WITH RELAPSED OR REFRACTORY AGGRESSIVE B-CELL NON-HODGKIN LYMPHOMA
Muhammad Furqan Internal Medicine AGRESSIVE B-CELL NON HODGKIN LYMPHOMA
3 years
A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in Subjects With Relapsed Small Cell Lung Cancer After Platinum-based First-line Chemotherapy (DeLLphi-304)
Muhammad Furqan Internal Medicine Elicio Therapeutics, Inc.
3 years
First in Human Phase 1/2 Trial of ELI-002 7P Immunotherapy as Treatment for Subjects with Kirsten Rat Sarcoma (KRAS)/Neuroblastoma RAS viral oncogene homolog (NRAS) Mutated Solid Tumors
Hillel Haim Microbiology ViiV Healthcare
5 years
Computational platform to personalize Fostemsavir treatment to people living with HIV-1 
Asad Javed Internal Medicine Lyell Immunopharma, Inc. 
3 years
A Phase 1 Study to Assess the Safety and Efficacy of LYL845 in Adults with Relapsed and/or Refractory Metastatic or Locally Advanced Melanoma and Selected Solid Tumor Malignancies
Mohammed Milhem Internal Medicine Merck Sharp & Dohme LLC
8 years
A Phase 3, Randomized, Double-blind, Active-Comparator-Controlled Clinical Study of Adjuvant MK-7684A (Vibostolimab with Pembrolizumab) Versus Adjuvant Pembrolizumab in Participants with High-risk Stage II-IV Melanoma (KEYVIBE- 010)
Sneha Phadke Internal Medicine Arvinas Estrogen Receptor Inc.
3 years
An Open-Label, Randomized, Non-Comparative Phase 2 Study of ARV-471 or Anastrozole in Post-Menopausal Women With ER+/HER2- Breast Cancer in the Neoadjuvant Setting
Philip Polgreen Internal Medicine Pfizer, Inc
4 months
Developing approaches to estimate a more accurate measure of the burden of influenza
Ernesto Ruiz Duque Internal Medicine Bristol-Myers Squibb Company
3 years
ODYSSEY-HCM
Lucy Wibbenmeyer Surgery PolyNovo Biomaterials Pty Ltd.
3 years
Pivotal Study to Assess the Safety and Effectiveness of NovoSorb Biodegradable Temporizing Matrix (BTM) in the Treatment of Severe Burn Skin Injuries

 

July 2023

New Federal Awards:
    Top of Page
Alexandra Bova Neurology NIH F32
1 year
Nigrostriatal dopamine mechanisms of cognitive control
Martine Dunnwald Anatomy & Cell Biology NIH R03
1 year
Popliteal Pterygium syndrome, IRf6, and the periderm
Adam Dupuy Anatomy & Cell Biology US DoD, CDMRP
HT9425-23-1-0780
3 years
ME220036 Identification of genetic mechanisms driving transition of benign nevi to malignant melanoma
Oliver Gramlich Ophthlamology NIH R03
5 years
Targeting Cholesterol Homeostasis to maintain vision in MS-like optic neuritis
Xiaoyang Hua Otolaryngology NIH R01
5 years
The nose-lung cross talk in upper respiratory virus infection induced asthma exacerbations
Miles Pufall Biochemistry & Molecular Biology US National Science Foundation
2324615
3 years
NSF/MCB-BSF: The effect of transcription factor binding on UV lesion accumulations
Chen Tan Internal Medicine NIH R01
2 years
NK cell responses to JC polyomavirus
Tomohiro Tanaka Internal Medicine US DoD, CDMRP
k08
5 years
Estimating the Causal Effect of Liver Allocation Policy Reflecting the Heterogeneity from Age and Geography
Kristina Thiel OBGyn US DoD, CDMRP
HT9425-23-1-0744
4 years
CA220729P1 - Progestin therapy for endometrial cancer

 

Other Awards:
     
Loreen Herwaldt Internal Medicine University of Wisconsin-Madison
2 years
Povidone-iodine to Stop Access-Related Infections and Transmission of Staphylococcus Aureus (PAINTS)
Katie Larson Ode Pediatrics Worldwide Clinical Trials, Inc.
3 years
A Phase 3, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and  Safety of Setmelanotide in Patients with Acquired Hypothalamic Obesity
Kelly Mulfaul Ophthalmology

BrightFocus Foundation
3 years

Investigating Human Choroidal Macrophage Recruitment and Activation in Age-related Macular Degeneration - Mulfaul 2022 - BrightFocus
Sneha Phadke Internal Medicine Olema Pharmaceuticals, Inc.
3 years
A Phase 1b Open-Label Multicenter Study of OP-1250 in Combination with the CDK4/6 Inhibitor Ribociclib or with the PI3K Inhibitor Alpelisib in Adult Subjects with Advanced and/or Metastatic HR Positive, HER2 Negative Breast Cancer
Donna Santillan, Contact PI
Mark santillan, MPI
OBGyn Heartland Health Research Alliance, LTD
3 years
Heartland
Tomohiro Tanaka Internal Medicine PPD Investigator Services, LLC
3 years
Phase 3 Multicenter, Randomized, Double-Blind, Study to Assess the Efficacy and Safety of Treatment with Bepirovirsen in HBeAg-negative Nucleos(t)ide Analogue-treated Participants with Chronic Hepatitis B Virus (B-Well 1)
George Weiner Internal Medicine V Foundation for Cancer Research
4 years
T cell help and resistance to anti-cancer monoclonal antibody therapy
Yousef Zakharia Internal Medicine Astellas Pharma Global Development, Inc.
3 years
A Phase 1 Study of ASP1002 in Participants with Metastatic or Locally Advanced Solid Tumors
Yousef Zakharia Internal Medicine AstraZeneca LP
3 years
A Phase III Randomized, Open-Label, Multicenter Study to Determine the Efficacy and Safety of Durvalumab in Combination With Tremelimumab and Enfortumab Vedotin or Durvalumab in Combination With Enfortumab Vedotin for Perioperative Treatment in Patients I

 

June 2023

New Federal Awards:
    Top of Page
Marina Del Rios Emergency Medicine NIH R01
4 years
Dime la VerDAD - Verify, Debunk, and Disseminate
Joel Geerling Neurology NIH R01
5 years
Brainstem cold-defense circuitry
Corinne Griguer Radiation Oncology NIH R01
5 years
Mitochondria electron transport chain complexes adaptative responses to cellular stress
John Harty Pathology NIH R21
2 years
Regulating Pathogen-induced Protective and Pathogenic CD8 T cells in the CNS
Diana Jalal, Contact PI
Richard Smith, MPI
Internal Medicine,
Otolaryngology
NIH R01
5 years
The Alternative Pathway of Complement: A Potential Contributor to Adverse Outcomes in CKD
Benjamin Kelvington Neuroscience & Pharmacology NIH F31
3 years
Defining the molecular impact of 16p11.2 deletion on reward response in striatal dopamine receptor D1-expressing neurons
Scott Lieberman Pediatrics NIH R01
5 years
Tyk2 and Associated Cytokines in Salivary Gland Autoimmunity
Allison Momany Pediatrics NIH K99
2 years
Neonatal Stress in Very Preterm Infants: Longitudinal Effects on Epigenetics and Neurodevelopment 
Andrew Sullivan Neuroscience & Pharmacology NIH F31
3 years
The Role of IRX3 Neurons in the Regulation of Body Weight Homeostasis
 
Other Awards:
     
Ted Abel Neuroscience & Pharmacology George Mason University
5 years
Estradiol signaling pathways mediating sex differences in striatal synaptic plasticity
Sabarish Ayyappan Internal Medicine Mayo Clinic
3 years
Randomized phase 2 study with safety run-in of PD-1 inhibitor and IgG4 SIRP-Fc fusion protein (TTI-622) and PD-1 inhibitor and IgG1 SIRP-Fc fusion protein (TTI-621) in relapsed Diffuse Large B-Cell Lymphoma (DLBCL)
Chandrikha Chandrasekharan Internal Medicine Astellas Pharma, Inc
3 years
A Phase 1/1b study of ASP2074 in participants with Metastatic or Locally Advanced solid tumors
Rami El Abiad Internal Medicine Ellodi Pharmaceuticals, L.P.
3 years
Fluticasone propionate Oral Dispersible Tablet Formulation in Eosinophilic Esophagitis: A Randomized, Double-blind, Placebo-Controlled 24-Week Induction Study of APT-1011, followed by a Single-arm Open-label Extension, in Adult Subjects with Eosinophilic 
Muhammad Furqan Internal Medicine Tempus Labs, Inc.
3 years
TEMPUS GEMINI NSCLC SURVEILLANCE STUDY
Jeremy Greenlee Neurosurgery Massachusetts Eye & Ear Infirmary Next-generation clinical phenotyping and pathophysiology of laryngeal dystonia and voice tremor, Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor (Project 3)
Serena Gumusoglu OBGyn Burroughs Wellcome Fund
4 years
Next Gen Pregnancy Initiative
Patrick McGonagill Surgery CSL Behring LLC
3 years
CSL Behring TAP Study
Jacob Michaelson Psychiatry Columbia University
1 year
Triangulation of missense variant impact through multimodal modeling and functional assays
Sneha Phadke Internal Medicine PSI Pharma Support America, Inc.
3 years
An Open-label Multicenter Phase 1b-2 Study of Elacestrant as Monotherapy and in Combination with Abemaciclib in Women and Men with Brain Metastasis from Estrogen Receptor Positive, HER-2 Negative Breast Cancer (ELECTRA)
Andrea Swenson Neurology Massachusetts General Hospital
2 years
An Expanded Access Protocol of Intravenous Trehalose Injection 90 mg/mL Treatment of Patients with Amyotrophic Lateral Sclerosis
Richard Tyler Otolaryngology Sage Therapeutics, Inc.
3 years
AN OPEN-LABEL STUDY EVALUATING THE SAFETY,  TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF  BREXANOLONE IN THE TREATMENT OF ADULT  PARTICIPANTS WITH TINNITUS

       

                           

May 2023

New Federal Awards:
    Top of Page
Bryan Allan, Contact PI
John Buatti, MPI
Radiation Oncology NIH R21
2 years
Redox manipulation of iron to improve glioblastoma therapy: A phase 1 trial
Polly Ferguson, Contact PI
Alaxander Bassuk, MPI
Pediatrics NIH K12
5 years
CTSA K12 PROGRAM AT THE UNIVERSITY OF IOWA
Donna Santillan ObGyn NIH R25
5 years
Beginning and Early Stage Translational (BEST) Researchers
Seth Tomchik Neuroscience & Pharmacology NIH R01
1 year
Mechanisms of Nf1 Pathophysiology Underlying Hyperactivity
Ergun Uc, Contact PI
Nandakumar Narayanan, MPI
Soura Dasgupta, MPI
Neurology,
Electrical & Computer Engineering

NIH RF1
3 years

Linear predictive coding of EEG Activity for Diagnosis of Parkinson's Disease (LEAD-PD)
 
Competitive Awards:
     
Bruce Gantz Otolaryngology NIH P50
5 years
Iowa Cochlear Implant Clinical Research Center VIII
 
Other Awards:
     
Chandrikha Chandrasekharan Internal Medicine Pharmaceutical Research Associates
3 years
A randomised, open-label, Phase II, dose/schedule optimisation study of NUC-3373/leucovorin/irinotecan plus bevacizumab (NUFIRI-bev) versus 5-FU/leucovorin/irinotecan plus bevacizumab (FOLFIRI-bev) for the treatment of patients with previously treated...
Alicia Gerke Internal Medicine Merck Sharp & Doheme LLC
3 years
INSIGNIA-COPD
Marlan Hansen Otolaryngology Akouos, Inc
3 years
A Phase 1/2 Trial of AAVAnc80-hOTOF Gene Therapy in Individuals with  Sensorineural Hearing Loss due to Biallelic Otoferlin Gene (OTOF) Mutations
Tahaunty Pena Internal Medicine Renovion, Inc.
3 years
A Phase 3 Open-Label, Randomized, Standard of Care-controlled Parallel Arm Study to Demonstrate Efficacy and Safety of ARINA-1 in the Prevention of Bronchiolitis Obliterans Syndrome (BOS) Progression in Participants with Bilateral Lung Tr
Andrea Swenson Neurology Massachusetts General Hospital
3 years
HEALEY ALS Platform Trial, Task 12
Michael Tomasson Internal Medicine Pfizer, Inc.
3 years
A PHASE 1B, OPEN-LABEL STUDY OF ELRANATAMAB IN COMBINATION WITH CARFILZOMIB PLUS DEXAMETHASONE IN PARTICIPANTS WITH RELAPSED REFRACTORY MULTIPLE MYELOMA
Douglas Van Daele Otolaryngology Nyxoah SA
3 years
ACCCESS Study - A multicenter study to assess the safety and effectiveness of the Genio dual-sided hypoglossal  nerve stimulation system for the treatment of obstructive sleep apnea in subjects with complete concentric collapse of the soft palate.
Patricia Winokur Internal Medicine Pfizer, Inc
3 years
A PHASE 3 MASTER PROTOCOL TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF RESPIRATORY SYNCYTIAL VIRUS (RSV) PREFUSION F SUBUNIT VACCINE IN ADULTS AT HIGH RISK OF SEVERE RSV DISEASE

 

April 2023

New Federal Awards:
    Top of Page
Mahmoud Abou Alaiwa Internal Medicine NIH R01
5 years
Contribution of Small Airways to Mucociliary Transport Dysfunction
Hillel Haim Microbiology NIH R01
4 years
Predicting HIV-1 escape from therapeutics in vitro and in vivo - toward personalizing medicine for people living with HIV
Vincent Magnotta Radiology NIH S10
1 year
University of Iowa - 7T Small Animal MRI Upgrade
Robert Roghair Pediatrics NIH R01
5 years
Sedentary behavior, physical activity, and 24-hour behavior in pregnancy and offspring health: the Pregnancy 24/7 Offspring Study
Robert Roghair Pediatrics NIH T35
5 years
Iowa Medical Student Summer Research Program in trans-NIDDK Research
Seth Tomchik Neuroscience & Pharmacology NIH R01
4 years
Genetic and molecular mechanisms of Nf1-dependent neuronal regulation of metabolism
Aislinn Williams Psychiatry Dod, CDMRP
3 years
AR220030_Validating tRNA viruses to target SCN2A-related autism phenotypes
 
Competitive Awards:
     
Tarah Colaizy Pediatrics NIH UG1
7 years
NICHD Cooperative Multicenter Neonatal Research Network
Peggy Nopoulos, Contact PI
John Wemmie, MPI
Psychiatry NIH T32
5 years
The Iowa Neuroscience Specialty Program in Research Education (INSPIRE)
Patrick Sinn Pediatrics NIH R01
4 years
Life-long phenotypic correction of CF airways
 
Other Awards:
     
Sabarish Ayyappan Internal Medicine Kite Pharma, Inc.
5 years
A Phase 2, Open-Label, Multicenter, Basket Study Evaluating the Safety and Efficacy of Brexucabtagene Autoleucel in Adults with Rare B-cell Malignancies (ZUMA-25)
Chandrikha Chandrasekharan Internal Medicine Pfizer, Inc.
3 years
A PHASE 1, OPEN-LABEL, MULTI-CENTER, DOSE ESCALATION AND DOSE EXPANSION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PRELIMINARY EVIDENCE OF ANTI-TUMOR ACTIVITY OF PF-07284892 (ARRY-558) AS A SINGLE
Umar Farooq Internal Medicine Kure.ai
3 years
CASE2422 A phase 1 single arm, open label study to evaluate the safety of UF-KURE19 cells in patients with relapsed or refractory B cell non-Hodgkin lymphomas.
Muhammad Furqan Internal Medicine AstraZeneca Pharmaceuticals LP
3 years
A Phase III, Randomised, Open-label, Multicentre, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin Versus Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line
Steven Lentz Internal Medicine Novo Nordisk, Inc
3 years
Frontier 4
Steven Lentz Internal Medicine Novartis Pharmaceuticals Corporation
3 years
A PHASE 1B, OPEN-LABEL STUDY TO ASSESS THE  SAFETY, EFFICACY, PHARMACOKINETICS, AND  PHARMACODYNAMICS OF ALPN-303 IN SUBJECTS  WITH AUTOIMMUNE CYTOPENIAS (RUBY-4)
Janet Pollard Radiology Novartis Pharmaceuticals Corporation
3 years
PSMAddition: An International Prospective Open-label, Randomized, Phase III Study comparing 177Lu-PSMA-617 in combination with Standard of Care, versus Standard of Care alone, in adult male patients with Metastatic Hormone Sensitive Prostate
Erin Shriver Opthalmology Viridian Therapeutics, Inc
3 years
A Multiple Ascending Dose (MAD) Safety, Tolerability and Efficacy Study of VRDN-001, A Humanized Monoclonal Antibody Directed Against the IGF-1 Receptor, in Normal Healthy Volunteers (NHVs) and Subjects With Thyroid Eye Disease (TED)

 

March 2023

New Federal Awards:
    Top of Page
Zuhair Ballas Internal Medicine NIH S10
1 year       
Full Spectrum Cell Sorter Flow Cytometer
Maya Evans Psychiatry NIH F21
1 year
Cellular and molecular investigations of striatal enlargement
in prenatal stress model of neurodevelopmental risk
Marlan Hansen, Contact PI
Patricia Winokur, MPI
Otolarygology,
Internal Medicine
NIH UM1 
7 years
University of Iowa Institute for Clinical and Translational
Science
Robert Roghair Pediatrics NIH T35
5 years
Medical Student Summer Research Program
Maria Spies, Contact PI
Michael Spies, MPI
Biochemistry & Molecular
Biology, PSET
NIH R21
2 years
Natural products inhibitors targeting homology-directed DNA
repair for cancer therapy
Stefan Strack Neuroscience,
Pharmacology
NIH R21
2 years
Interplay between tau and PKA condensates in ADRD
Seth Tomchik   NIH R01
5 years
Mechanisms of compartmentalized plasticity in learning and memory
 
Competitive Awards:
     
David Gordon Pediatrics NIH R37
2 years
Gene expression signature based screening in Ewing sarcoma
Jia Luo Pathology NIH R01
5 years
Endoplasmic Reticulum Stress and Alcohol neurotoxicity
David Weiss, Contact PI
Regina McGrane, MPI
Mirobiology NSF
3 years
REU Site: Microbiology at the host-pathogen interface
 
Other Awards:
     
John Bernat Pediatrics Sanofi US Services, Inc
3 years
A Phase 3, Multicenter, Multinational, Randomized, Double-Blind, Double-Dummy, Active-Comparator Study to Evaluate the Efficacy and Safety of Venglustat in Adult and Pediatric Patients with Gaucher Disease Type 3 (GD3) Who have Reached Therapeutic Goals w
Muhammad Furqan Internal Medicine Immunocore Limited
3 years
A Phase 1/2 First-in-Human Study of the Safety and Efficacy of IMC-F106C as a Single Agent and in Combination with Checkpoint Inhibitors in HLA-A*02:01-Positive Participants with Advanced PRAME-Positive Cancers
Katherine Mathews Pediatrics Virginia Commonwealth University
3 years
GRASP-01-002- Defining Clinical Endpoints in Becker Muscular Dystrophy
Praveen Vikas Internal Medicine Pharmaceutical Research Associates
3 years
A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Do Not Express PD-L1 or in
Daniel Berg Internal Medicine Astellas Pharma Global Development, Inc
3 years
A Phase 2, Open-Label, Randomized Study to Assess the Efficacy and Safety of Zolbetuximab (IMAB362) in Combination with Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects with Claudin 18.2 (CLDN18.2) Positive, Metastatic Panc
Tomohiro Tanaka Internal Medicine PPD Investigator Services, LLC
3 years
A Randomized, Double-blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F2 to F4 Fibrosis
Alejandro Comellas Freymond Internal Medicine AstraZenica AB
3 years
A Phase III, Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Tozorakimab (MEDI3506) in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen (TILIA).
Antonio Sanchez Internal Medicine Zydus Therapeutics Inc
3 years
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 2b/3 Study to Evaluate the Efficacy and Safety of Saroglitazar Magnesium in Subjects with Primary Biliary Cholangitis
Andrea Swenson Neurology Massachusetts General Hospital
3 years
HEALEY ALS Platform Trial, Task # 11
Steven Polyak Internal Medicine TriNetX
2 years
A Retrospective Observational Study of the Standard of Care, and Medical and Surgical Treatment Patterns in Crohn's Perianal Fistulas (CPF) in the U.S.

 

February 2023

New Federal Awards:
    Top of Page
Ernesto Fuentes Biochemistry NIH R01
5 years
Molecular Mechanisms Regulating Bacterial Two-component Signaling Systems
Kristin Claflin Neuroscience & Pharmacology NIH K01
5 years
Regulation of neuronal function by mitochondrial uncoupling
Georgina Aldridge Neurology NIH R01
5 years
Cortical Alpha-Synuclein in Dementia
Markus Kuehn Ophthalmology NIH R01
4 years
T-cell mediated RGC damage in glaucoma
Damian Krysan Pediatrics NIH R21
2 years
Systematic Genetic Analysis of C. albicans CNS Infection
 
Competitive Awards
     
Noah Butler Microbiology NIH R01
5 years
Development and function of CD4+ memory T cells during malaria
Noah Butler Microbiology NIH R01
5 years
Regulation of Plasmodium-specific CD4+ T cells
Richard Smith - Contact PI
Carla Nester - MPI
Patrick Breheny - MPI
Otolaryngology, Pediatrics,
and Biostatistics
NIH R01
5 years
C3 Glomerulopathy - A Collaborative Study
Alexander Bassuk Pediatrics NIH K12
5 years
Molecular and Cellular Research to Advance Child Health
 
Other Awards
     
Ferhaan Ahmad Internal Medicine Cytokinetics, Inc
3 years
SEQUOIA-HCM OLE
Stephan Arndt Psychiatry Northeast Iowa Behavioral Health
4 years
Evaluation project: Certified Community Behavioral Health Clinic Planning, Development, and Implementation Grant (CCBHC)
John Bernat Pediatrics AVROBIO, Inc
3 years
A Follow-Up Study of Subjects with Type 1 Gaucher Disease Who Previously Received AVR-RD-02
Linda Cadaret Internal Medicine Acceleron Pharma, Inc
3 years
SOTERIA: An Open-Label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH
Chandrikha Chandrasekharan Internal Medince CG Pharmaceuticals, Inc
3 years
A Phase 1b/2, Dose-escalation, Randomized, Multicenter Study of Maintenance Ivaltinostat plus Capecitabine or Capecitabine Monotherapy in Patients with Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on First Line FOLFIRINOX Chemoth
Rami El Abiad Internal Medince AstraZenica Pharmaceuticals LP
3 years
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase III Efficacy and Safety Study of Tezepelumab in Patients with Eosinophilic Esophagitis
Umar Farooq Internal Medince PRA Health Sciences
3 years
Long-term Follow-up Protocol for Subjects Treated with Adicet Allogeneic Gamma Delta () CAR T Cell Investigational Products
Asad Javed Internal Medince Replimune, Inc
3 years
An Open-Label, Multicenter, Phase 1 Study of RP3 as a Single Agent and in Combination with PD-1 Blockade in Patients with Solid Tumors
Douglas Laux Internal Medince Incyte Biosciences Internal S.a.r.l.
3 years
A Randomized, Double-Blind, Multicenter, Phase 2 Study of Retifanlimab in Combination With INCAGN02385 (Anti-LAG-3) and INCAGN02390 (Anti-TIM-3) as First-Line Treatment in Participants With PD-L1-Positive (CPS  1) Recurrent/Metastatic Squamous Cell Carci
Margarida Magalhaes-Silverman Internal Medince Equillium, Inc.
3 years
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination with Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease
Varun Monga Internal Medince Medpace Clinical Research, LLC
3 years
A Randomized, Blinded, Placebo-controlled, Phase 2 Study of INBRX-109 in Unresectable or Metastatic Conventional Chondrosarcoma
Lama Noureddine Internal Medince Otsuka Pharmaceutical Development & Commercialization, Inc.
3 years
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate  the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with  Immunoglobulin A Nephropathy Trial of Sibeprenlimab in the Treatment of Immunogl
Stefan Strack, Contact PI
Marie Gaine, MPI
Neuroscience & Pharmacology Eagles Autism Foundation
2 years
Primary PKA Dysregulation in Marbach-Schaaf Neurodevelopmental Syndrome
Patricia Winokur Internal Medince Pfizer, Inc.
3 years
A PHASE 1/2 RANDOMIZED, OBSERVER-BLIND STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A MODIFIED RNA VACCINE AGAINST VARICELLA ZOSTER VIRUS IN HEALTHY INDIVIDUALS

 

January 2023

New Federal Awards:
    Top of Page
Bao Vu Molecular Physiology & Biophysics NIH R21
2 Years         
Functional and transcriptome analyses of protein kinases in Candida glabrata antifungal drug resistance
Brandon Davies Biochemistry & Molecular Biology NIH R01
5 Years
Regulation of Endothelial Lipase and HDL Metabolism by ANGPTL3
Chris Ahern, Contact PI
Barry London, MPI
Molecular Physiology & Biophysics NIH R01
4 Years
A Versatile Chemical-Genetic Approach to Determine Bases for Arrhythmogenesis and Sodium Channelopathies
Chris Ahern Molecular Physiology & Biophysics NIH R35
5 Years
Chemical Biology of Voltage-Gated Cation Channels
David Stoltz Internal Medicine NIH T32
5 Years
Climate Change and Lung Health Training Program
Enrique Leira, Contact PI
Anil Chauhan, MPI
Neurology & Internal Medicine NIH U01
3 Years
The University of Iowa Stroke Preclinical Assessment Network to Support Translational Studies for Acute Cerebroprotection
Kevin Legge Pathology NIH R01
5 Years
Protection and Immunity after Polyanhydride Nanoparticle Vaccination against Avian Influenza A Virus
M Washington Biochemistry & Molecular Biology NIH R35
5 Years
Structural and mechanistic studies of DNA bypass pathways in eukaryotes
Nikolai Artemyev Molecular Physiology & Biophysics NIH R01
4 Years
Molecular underpinnings of photoreceptor transcriptional regulation by CRX and NRL
Santiago Ortega Gutierrez Neurology NIH R03
2 Years
Novel risk stratification score for patients with acute Cerebral Venous Thrombosis
 
Other Awards: 
     
Brian Link Internal Medicine Mayo Clinic (Prime: Genetech)
3 Years
Characteristics and Outcomes of Patients with Diffuse Large B-Cell Lymphoma (DLBCL) at Least Two Prior Lines of Systemic Therapy and Treated at Cancer Centers Within the LEO Cohort
Chandrikha Chandrasekharan Internal Medicine Pfitzer, Inc
3 Years
A PHASE 1, OPEN-LABEL, DOSE ESCALATION AND EXPANSION STUDY OF PF-07265028 AS A SINGLE AGENT AND IN COMBINATION WITH SASANLIMAB EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTI-TUMOR ACTIVITY OF PF-07265028 IN PARTICIPANTS
Christopher Strouse Internal Medicine ICON Clinical Research, LLC (Prime: Takeda)
3 Years
A Phase 1b Open-label Study to Evaluate the Safety and Tolerability of Intravenous Modakafusp Alfa as Part of Combination Therapy in Adult Patients with Multiple Myeloma
Douglas Hornick Internal Medicine AN2 Therapeutics
3 Years
A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter, Prospective Study to Assess the Efficacy, Safety, and Pharmacokinetics of Orally Administered Epetraborole in Patients with Treatment-refractory Mycobacterium avium Complex Lung Disease
Frank Faraci Internal Medicine LeDucq Foundation
5 Years
Brain Endothelium: A Nexus for Cerebral Small Vessel Disease
Grerk Sutamtewagul Internal Medicine Pharmaceutical Research Associates (Prime: Gilead Sciences)
3 Years
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study  Evaluating the Safety and Efficacy of Magrolimab versus Placebo in  Combination with Venetoclax and Azacitidine in Newly Diagnosed,  Previously Untreated Patients with Acute Myeloid Leukemia
Jon Houtman Cancer Center American Cancer Society
3 Years
Iowa Cancer Research Experience (ICARE)
Katherine Mathews Pediatrics Asklepios BioPharmaceutical, Inc.
3 Years
A two-part multicenter study: a randomized, double-blind, placebo-controlled dose-escalation safety and bioavailability phase (Part 1) followed by double-blind, placebo-controlled, adaptive phase (Part 2) study to evaluate the safety and efficacy of LION-
Katherine Mathews Pediatrics Lexeo Theraputics
6 Years
A Phase 1/2 Study of the Safety and Efficacy of LX-2006 Gene Therapy in Friedreich's Ataxia
Michael Ohl Internal Medicine Iowa Department of Public Health (Prime: SAMHSA)
1 Year
The Integrated Addiction Care Coordination and Essential Support Services (iACCESS)
Muhammad Furqan Internal Medicine Amgen, Inc.
3 Years
A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of Tarlatamab in Subjects with Relapsed/Refractory Small Cell Lung Cancer After Two or More Prior Lines of Treatment
Rami El Abiad Internal Medicine Celgene International II SARL LC
3 Years
A PHASE 3, MULTICENTER, MULTINATIONAL, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY OF CC-93538 IN ADULT AND ADOLESCENT SUBJECTS WITH EOSINOPHILIC ESOPHAGITIS
Saima Sharif Internal Medicine GlaxoSmithKline LLC
9 Years
Phase II, Single Arm Study of Neoadjuvant Dostarlimab (TSR-042) in Stage II and III Deficient Mismatch Repair Colon Cancers
Seth Tomchik Neurosciences & Pharmacology Texas A&M University (Prime: NIH)
2 Years
The role of Nf1 in sleep-dependent regulation of metabolic function
Umar Farooq Internal Medicine Caribou Biosciences, Inc.
3 Years
A Phase 1, Multicenter, Open-Label Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Varun Monga Internal Medicine C4 Therapeutics, Inc.
3 Years
Phase1/2 open-label multicenter study to characterize the safety and tolerability of CFT8634 in subjects with locally Advanced or Metastatic SMARCB1 perturbed cancers Including Synovial Sarcoma and SMARCB1-Deleted Solid Tumors
Xingshen Sun Anatomy & Cell Biology Cystic Fibrosis Foundation
3 Years
004590G222 Early life impact of CFTR modulators on the endocrine pancreas and diabetes in CF
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