• Past Seminar Speakers

     Fall 2016

    David Weiss, Department of Microbiology, University of Iowa
    Using fluorescemt proteins to illuminate bacterial cell division and pathogenesis  
    Chioma Okeoma, Department of Microbiology, University of Iowa
    BST-2 at the nexus of viral pathogenesis and cancer 

    Marvin Whiteley, Department of Biosciences, University of Texas at Austin
    The role of community composition and biogeography in polymicrobial infection

    Andrew Goodman, Microbial Sciences Institute, Yale University
    Microbiome offense and defense

    Hongbo Chi, Immunology Department, St. Jude Children's Research Hospital
    mTOR signaling and metabolic control of T cell fate decisions

    Aloysius J. Klingelhutz, Department of Microbiology, University of Iowa
    Why immortalize fat cells? Uncovering the roles of toxins in adipose dysfunction and type II diabetes 


    Spring 2016

    Andres Vazquez-Torres, Department of Immunology & Microbiology, University of Colorado School of Medicine
    Antioxidant defenses of thioredoxin independent of canonical thiol-disulfide oxidoreductase enzymatic activity 

    Hillel Haim, Department of Microbiology, University of Iowa
    Identifying the order that underlies randomness in HIV-1 evolution at the patient and population level

    Susan Hafenstein, Professor of Medicine & Microbiology and Immunology, Penn State College of Medicine
    Transformative advance in cryo-EM used to explore virus-host interactions
    Aimee Shen, Dept. of Microbiology & Molecular Genetics, University of Vermont
    Clostridium difficile spore formation and germination

    Samantha King, Pediatrics, Ohio State University
    Streptococcus oralis utilizes a novel mechanism of sequential adherence to host glycans

    Rita Tamayo, Department of Microbiology and Immunology, University of North Carolina
    Regulation of flagellum and cytotoxin biosynthesis in Clostridium difficile

    Heather Allen, Research Microbiologist at USDA-ARS
    Collateral effects of antibiotics on the swine gut microbiota

    Christopher Snyder, Thomas Jefferson University
    Co-sponsored with Immmunology (T cell responses against persistent viral infections) 

    Ian Hewson, Department of Microbiology, Cornell University
    The sea star microbiome orchestra:  Old players on a new stage

    Susan K. Pierce, PhD, Chief, Laboratory of Immunogenetics, NIH/NIAID
    The immune response to malaria:  What malaria knows about the immune system that Immunologists don't

    Thomas Gallagher, Department of Microbiology & Immunology, Loyola University Chicago
    MERS Coronavirus - Cell Entry

    Fall 2015

    John V. Williams, Division of Pediatric Infectious Diseases, Children's Hospital of Pittsburgh
    Why Pulmonary CD8 T Cells Won't Fight, Fight, Fight for Iowa

    Blaise R. Boles, Department of Microbiology, University of Iowa
    Fold modulating function: Functional amyloids produced by Staphylococcus aureus

    Dorian McGavern, National Institute of Neurological Disorders and Stroke, NIH
    Real-time insights into the regulation of sterile vs. antimicrobial CNS immunity

    Christopher Waters, Department of Microbiology & Molecular Genetics, Michigan State University
    Cyclic di-GMP: A global regulatory maestro that orchestrates the adaptation of bacteria to changing environments

    Melissa B. Lodoen, Molecular Biology and Biochemistry, University of California Irvine
    Host-Parasite Interactions, Immunity, and Pathogenesis

    Moriah L. Szpara, Biochemistry and Molecular Biology, Penn State University
    Variability, adaptation, and evolution in alpha-herpesviruses

    Matthew Wargo, Department of Microbiology & Molecular Genetics, University of Vermont
    Pseudomonas detection of host-derived amines using a particular sub-family of AraC-like regulators

    Alexander R. Horswill, Department of Microbiology, University of Iowa
    The social life of Staphylococci

    Catharine Bosio, National Institute of Allergy and Infectious Diseases, NIH
    Building a Better Mousetrap: Using Classic Immunology to Develop Effective Tularemia Vaccines

    Katherine P. Lemon, The Forsyth Institute
    Nose Picking for Progress: Mining the Nasal Microbiome for New Insights into Pathobionts

    Elsa Bou Ghanem, Department of Molecular Biology and Microbiology, Tufts University School of Medicine
    The role of neutrophils and extracellular adenosine in shaping host resistance to Streptococcus pneumoniae lung infection

    Drew Kitchen, Department of Anthropology, University of Iowa
    Evolutionary genetics reveal the shared history of humans and our parasites and pathogens

    Mishtu Dey, Department of Chemistry, University of Iowa
    Structural enzymology of mononuclear non-heme iron enzymes

    Elsa Bou Ghanem, Molecular Microbiology Program, Tufts University
    The role of neutrophils and extracellular adenosine in shaping host resistance to Streptococcus pneumoniae lung infection

    Qi Yang, Department of Pathology & Laboratory Medicine, University of Pennsylvania
    Development and function of innate lymphoid cells

    Aaron G. Schmidt, Department of Pediatrics, Boston Children's Hospital
    Immuno-viral archaeology: Uncovering history of antigen exposure and mechanisms of antibody affinity maturation

    Spring 2015

    George Dimopoulos, Department of Molecular Microbiology and Immunology, Johns Hopkins University
    The mosquito microbiota in disease transmission

    Margaret Kielian, Department of Cell Biology, Albert Einstein College of Medicine
    Enveloped virus entry: Mechanisms and regulation of membrane fusion

    Tom Bobik, Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University
    Bacterial microcompartments, widespread prokaryotic organelles for metabolic optimization

    Victor J. DiRita, Department of Microbiology & Immunology, University of Michigan
    Campylobacter colonization mechanisms in a natural host model

    Shaden Kamhawi, National Institute of Allergy and Infectious Diseases, NIH
    The influence of vector-derived factors on Leishmania transmission and disease progression

    Kevin B. Urdahl, Department of Immunology, University of Washington
    Understanding and overcoming the barriers to T cell mediated immunity against tuberculosis

    Ilya V. Frolov, Department of Microbiology, University of Alabama Birmingham
    Let's make our knowledge of virus-host interactions useful. Engineering of alphaviruses with programmed phenotypes

    Pradeep Singh, Department of Microbiology, University of Washington
    Regional lung evolution produces bacterial diversity during cystic fibrosis infections

    Martin L. Moore, Department of Pediatrics, Emory University School of Medicine
    Interaction of the respiratory syncytial virus fusion protein with epidermal growth factor receptor

    Thomas J. Braciale, Department of Pathology, University of Virginia
    Dendritic cells and the control of antiviral effector and memory T cell responses during respiratory virus infection

    Steve Melville, Department of Biological Sciences, Virginia Tech
    Looking at Type IV pili at the cellular and atomic level

    Lauren O. Bakaletz, The Research Institute at Nationwide Children's Hospital
    Extracellular DNA-associated DNABII proteins as a target for disruption of biofilms formed by nontypeable Haemophilus influenzae

    Fall 2014

    Robin G. Lorenz, Department of Pathology, University of Alabama Birmingham
    The role of p-glycoprotein in intestinal inflammation

    Guido Silvestri, Pathology & Laboratory Medicine, Emory University
    Target cell restriction in AIDS pathogenesis and eradication

    Hector Aguilar-Carreno, Veterinary Microbiology and Pathology, Washington State University
    Multiple Glycoprotein Functions of a Deadly CONTAGION: Nipah Virus

    Steven M. Varga, Department of Microbiology, University of Iowa
    The Good, the Bad and the Ugly Consequences of CD8 T Cell Memory to RSV

    E. Peter Greenberg, Department of Microbiology, University of Washington
    Microbial social engineering: Control of cooperation in Pseudomonas aeruginosa

    Gregory A. Smith, Department of Microbiology-Immunology, Northwestern University
    Alphaherpesviruses in the spotlight: a neuroinvasive nanomachine in action

    Matthew C. Wolfgang, Department of Microbiology and Immunology, University of North Carolina
    Reciprocal regulation of cyclic AMP signaling drives acute and chronic virulence phenotypes in Pseudomonas aeruginosa

    Zuoan Yi, Department of Microbiology, University of Iowa
    The regulation of T cells in specialized tissue microenvironments

    M. Suresh, Department of Pathobiological Sciences, University of Wisconsin
    Signaling and Transcriptional Basis of T-Cell Memory

    Ann M. Stock, Center for Advanced Biotechnology and Medicine, Rutgers University
    Insights into Two-Component System Architecture from Phosphorylation Profiling: Enough is Enough

    Hilde Cheroutre, La Jolla Institute for Allergy and Immunology
    Mucosal T cells: Same Players Different Strategies

    Joseph Dillard, Medical Microbiology & Immunology, University of Wisconsin
    Breaking down the wall: Peptidoglycan degradation and the pathogenesis of Neisseria gonorrhoeae

    Wendy Maury, Department of Microbiology, University of Iowa
    The Role of TIM Proteins in Ebola Virus Infection

    Gabriel Nunez, Department of Pathology, University of Michigan
    Linking Pathogen Virulence, the Microbiota and Immunity

    Spring 2014

    Pamela Hall, Department of Pharmaceutical Sciences, University of New Mexico
    Pharmacological disruption of agr quorum sensing in Staphylococcus aureus protects against skin and soft tissue infection

    David Weiss, Emory Vaccine Center, Emory University
    CRISPR/Cas-mediated endogenous gene regulation is required for bacterial innate immune evasion

    Kim Lewis, Department of Biology, Northeastern University
    Persisters and the quest for a biofilm-sterilizing antibiotic

    Christine Petersen, Department of Epidemiology, University of Iowa
    Lessons from a Tropical Disease in the Midwest

    Jenny Gumperz, Medical Microbiology & Immunology, University of Wisconsin-Madison
    Linking NKT cells to Inflammation

    Shan-Lu Liu, Molecular Microbiology & Immunology, University of Missouri
    New Cellular Factors Modulating Viral Infections

    S. Celeste Morley, Department of Pediatrics, Washington University School of Medicine in St Louis
    Immunodeficiency as a movement disorder: impaired immunity in mice deficient for L-plastin

    Robert Schleif, Department of Biology, Johns Hopkins University
    The Bottom Line on the Regulatory Protein AraC (240 Person-years of work)

    Dennis W. Metzger, Center for Immunology & Microbial Disease, Albany Medical College
    Influenza and Secondary Bacterial Pneumonia Mechanisms

    George A. O'Toole, Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth
    To Build a Biofilm

    Daniel Zurawski, Walter Reed Army Institute of Research
    Defining an appropriate strain and developing animal models to study Acinetobacter baumannii pathogenesis and novel antimicrobials

    Ekaterina Heldwein, Department of Molecular Biology & Microbiology, Tufts University
    Herpesviruses on the way out: what structures and biophysics can tell us

    Fall 2013

    John Kirby, Department of Microbiology, University of Iowa
    Chemosensory regulation of microbial communities

    William Goldman, Department of Microbiology & Immunology, University of North Carolina
    The Progression of Pneumonic Plague

    Craig Ellermeier, Department of Microbiology, University of Iowa
    A Bacterial Receptor for Lysozyme Controls σ Factor Activation and Lysozyme Resistance

    Wilmara Salgado-Pabón, Department of Microbiology, University of Iowa
    Molecular Pathogenesis of Staphylococcal Infective Endocarditis

    Steven McElroy, Department of Pediatrics, University of Iowa
    Untangling the Role of Bacteria in Development of Neonatal Necrotizing Enterocolitis 

    Keji Zhao, Laboratory of Epigenome Biology, National Heart Lung & Blood Institute
    Epigenetic regulation of T cell differentiation

    Erhard Bremer, Laboratory for Molecular Microbiology, University of Marburg, Germany
    The big fight of a small bacterium with osmotic challenges - cellular stress responses to a ubiquitous cue

    Peter Crompton, Laboratory of Immunogenetics, National Institute of Allergy & Infectious Diseases
    Unraveling the Mechanisms of Naturally-Acquired Immunity to Malaria

    Felipe Diaz-Griffero, Department of Microbiology & Immunology, Albert Einstein College of Medicine
    Innate immunity against HIV-1

    David Farrar, Department of Immunology, University of Texas Southwestern Medical Center
    Interfering with allergic diseases

    Douglas B. Weibel, Department of Biochemistry, University of Wisconsin
    Studying bacterial cell division and chromosome segregation using small molecules

    Carol Duffy, Department of Biological Sciences, University of Alabama
    Don't kill the messenger! Does the HSV-1 VP22 protein promote translation by preventing mRNA cleavage by a viral nuclease?

    Blaise Boles, Department of Molecular, Cellular, and Developmental Biology, University of Michigan
    Bacterial Functional Amyloids

    Jyoti Misra Sen, Immune Cells and Inflammation Section, National Institute on Aging
    T cell factor-1 regulated T cell development and function

    Kartik Chandran, Department of Microbiology & Immunology, Albert Einstein College of Medicine
    The lysosomal transporter Niemann-Pick C1 is a critical intracellular receptor for Ebola virus

    Donna Farber, Department of Surgery, Columbia University Medical Center
    Tissue compartmentalization of T cell responses in mice and man

    Spring 2013

    Keith Jarosinski, Department of Microbiology, University of Iowa
    Herpesvirus-induced oncogenesis and transmission

    Shelley M. Payne, University of Texas at Austin
    Shigella pathogenesis: Life in the intracellular environment

    Michael Schmidt, Medical University of South Carolina
    Bacteria, Burden and Bundles: How Copper Surfaces Enhance Patient Safety

    John Butler, Department of Microbiology, University of Iowa
    B cell and repertoire development in swine: a challenge of current paradigms

    Daniel C. DiMaio, Yale University
    Traptamers: artificial transmembrane proteins that inhibit HIV

    John-Demian Sauer, University of Wisconsin-Madison
    The role of inflammasome activation in the induction of cell mediated immunity

    Morgan Huse, Sloan-Kettering Institute
    Lipid-based patterning of the cytoskeleton at the immunological synapse

    Arturo Casadevall, Albert Einstein College of Medicine at Yeshiva University
    Thoughts on the origin of microbial virulence

    Kumaran S. Ramamurthi, National Cancer Institute
    Morphogenesis of large structures during development

    Stokes Peebles, Vanderbilt University
    IL-13 modulation of Th17 cytokine responses

    Michael S. Diamond, Washington University in St. Louis
    New insights into innate and adaptive immune responses against flaviviruses and alphaviruses

    Fall 2012

    Timothy L. Yahr, Department of Microbiology, University of Iowa
    The Pseuomonas aeruginosa type III secretion system: to be on or not to be on, that is the question

    Mark R. Denison, Vanderbilt University
    Coronavirus RNA proofreading: a novel determinant of evolution, replication, and pathogenesis

    Craig D. Ellermeier, Department of Microbiology, University of Iowa
    Activation of ECF sigma factors in response to cell envelope stress in Bacillus subtilis and Clostridium difficile

    Valley Stewart, University of California, Davis
    Transmitter phosphatase control of two-component signal transduction

    Jeffrey Rathmell, Duke University
    Lymphocyte metabolism in immunity and leukemia

    Stacey L. Schultz-Cherry, St Jude Children's Research Hospital
    Pathogenesis of RNA viruses: Fat mice and a viral enterotoxin

    William Shafer, Emory University
    Mechanisms of antibiotic resistance expressed by Neisseria gonorrhoeae: Implications for pathogenesis

    Dennis E. Ohman, Virginia Commonwealth University
    All Stressed Out: Adaptation of a Stress Response System in Pseudomonas for Pathogenesis in Cystic Fibrosis

    Victor J. Torres, New York University Langone Medical Center
    Staphylococcus aureus bi-component toxins: pore-forming toxins involved in the disarmament of the host surveillance system

    Thomas G. Bernhardt, Harvard Medical School
    The ABCs of bacterial cell division

    Carolyn Hovde Bohach, University of Idaho
    Cattle: The silent reservoir of E. coli O157:H7

    Allan Zajac, University of Alabama Birmingham
    Tuning CD8 T cell responses

    Tammy L. Kielian, University of Nebraska Medical Center
    S. aureus biofilms: identifying mechanisms of immune evasion and strategies for therapeutic intervention

    Patrick M. Schlievert, PhD, Department of Microbiology, University of Iowa
    Glycerol Monolaurate-Coenzyme Q Based Formations as Topical Microbicides