Stead Family Department of Pediatrics

Andrew Norris, MD, PhD


Associate Professor of Pediatrics  - Endocrinology and Diabetes
Associate Professor of Biochemistry

Contact Information

Primary Office: 1270B CBRB
Iowa City, IA 52242
Phone: 319-335-7383

Web: Norris Laboratory


BS, Chemistry, Massachusetts Institute of Technology
MD, Medicine, Washington University School of Medicine
PhD, Molecular Biology, Washington University School of Medicine

Residency, Pediatrics, University of Iowa Hospitals & Clinics
Fellowship, Pediatric Endocrinology, Children's Hospital Boston & Joslin Diabetes Center
Post Doctorate, Diabetes Research, Joslin Diabetes Center

Licensure and Certifications

Pediatric Endocrinology

Education/Training Program Affiliations

Department of Biochemistry PhD
Interdisciplinary Graduate Program in Informatics

Research Summary

Our work is currently focused on three questions. (1) How does fetal over- or under-exposure to macronutrients incite poor metabolism? To study this, we have developed an in vivo fetal model accomplished via unilateral infusion of macronutrients into the uterine artery. (2) How does cystic fibrosis cause diabetes? We are working collaboratively with other University of Iowa investigators to better understand the pathophysiology of cystic fibrosis related diabetes. (3) How does direct action on skeletal muscle of the thiazolidinediones and their target, the transcription factor PPARgamma, help treat diabetes? We have recently demonstrated that PPARgamma directly augments the PDK1:AKT nexus of insulin signaling despite increasing muscle lipid uptake.

Center, Program and Institute Affiliations

Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases
Fraternal Order of Eagles Diabetes Research Center
UI Obesity Research and Education Initiative

Date Last Modified: 06/06/2016 - 13:17:48