Ophthalmology And Visual Sciences

Seongjin Seo, PhD


Assistant Professor of Ophthalmology and Visual Sciences

Contact Information

Office: 4135F MERF
Iowa City, IA 52242
Phone: 319-353-4605

Lab: 4171 MERF
Iowa City, IA 52242

Email: seongjin-seo@uiowa.edu


BS, Biology Education, Seoul National University
Med, Biology, Seoul National University
PhD, Molecular Biology and Pharmacology, Washington University School of Medicine

Center, Program and Institute Affiliations

Stephen A. Wynn Institute for Vision Research

Selected Publications

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Seo S, Solivan-Timpe F, Roos B, Robin A, Stone E, Kwon Y, Alward W, Fingert J.  Identification of Proteins that Interact with TANK Binding Kinase 1 and Testing for Mutations Associated with Glaucoma.  Curr. Eye. Res..  2013 February. 38(2):310-5.

Humbert M, Weihbrecht K, Searby C, Li Y, Pope R, Sheffield V, Seo S.  ARL13B, PDE6D and CEP164 form a functional network for INPP5E ciliary targeting..  Proc. Natl. Acad. Sci. USA..  2012 November 27. 109(48):19691-6.

Zhang Q, Yu D, Seo S, Stone E, Sheffield V.  Intrinsic protein-protein interaction mediated and chaperonin assisted sequential assembly of a stable Bardet-Biedl syndrome protein complex, the BBSome..  J Biol Chem.  2012 April 12. 287(24):20625-20635.

Zhang Q, Seo S, Bugge K, Stone E, Sheffield V.  BBS proteins interact genetically with the IFT pathway to influence SHH related phenotypes..  Hum Mol Genet.  2012 January 6. 21(9):1945-1953.

Zhang Q, Nishimura D, Seo S, Vogel T, Morgan D, Searby C, Bugge K, Stone E, Rhamouni K, Sheffield V.  Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS associated phenotypes and Bbs3 unique phenotypes..  Proc. Natl. Acad. Sci. USA..  2011 December 2. 108(51):20678-20683.

Seo S, Zhang Q, Bugge K, Breslow D, Searby C, Nachury M, Sheffield V.  A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened..  PLoS Genet.  2011 November 3. 7(11):e1002358.

Seo S, Baye L, Schulz N, Beck J, Zhang Q, Slusarski D, Sheffield V.  BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.  Proc Natl Acad Sci U S A.  2010 January 26. 107(4):1488-93.

Seo S, Guo D, Bugge K, Morgan D, Rahmouni K, Sheffield V.  Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling.  Hum Mol Genet.  2009 April 1. 18(7):1323-31.

Rahmouni K, Fath M, Seo S, Thedens D, Berry C, Weiss R, Nishimura D, Sheffield V.  Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome.  J Clin Invest.  2008 April. 118(4):1458-67.

Seo S, Lim J, Yellajoshyula D, Chang L, Kroll K.  Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers.  EMBO J.  2007 December 12. 26(24):5093-108.

Date Last Modified: 06/06/2016 - 13:17:48