Ophthalmology And Visual Sciences

Randy H. Kardon, MD, PhD


Pomerantz Family Chair in Ophthalmology
Director, Neuro-Ophthalmology Service
Director, Iowa City VA Center of Excellence for Prevention and Treatment of Visual Loss
Professor of Ophthalmology and Visual Sciences

Contact Information

Primary Office: 11290D  PFP
Iowa City, IA 52242
Phone: 319-356-2260

Email: randy-kardon@uiowa.edu
Web: Dr. Kardon's Publications (from NCBI)
Web: Watch profile video
Web: UI Clinical Profile


BS, Pharmacology, University of Iowa
MD, Medicine, University of Iowa
PhD, Pharmacology, University of Iowa

Fellowship, Ophthalmology Research Fellow, Department of Ophthalmology, University of Iowa
Internship, Medicine, Gundersen Clinic & Lutheran Hospital
Residency, Ophthalmology, Department of Ophthalmology, University of Iowa
Fellowship, Neuro-Ophthalmology, Department of Ophthalmology, University of Iowa

Licensure and Certifications

ABO Certification, American Board of Ophthalmology
State of Iowa Medical License, Iowa Board of Medicine
Federal DEA
Iowa Controlled Substance

Education/Training Program Affiliations

Medical Scientist Training Program

Research Summary

I am Director of Neuro-ophthalmology at The University of Iowa and have been an active clinician scientist for over 25 years. Additionally I am Director of the Iowa City VA Center for Prevention and Treatment of Vision Loss, funded by the Department of Veterans Affairs, which organizes a group of over 20 scientists and clinicians towards studying and researching optic nerve and retinal disorders that have relevance to the military population, especially in relation to traumatic brain injury (TBI). I have expertise in the physiology of the melanopsin containing retinal ganglion cells (MGC) in humans and animals. Most recently, I have obtained funding and have published articles on using the pupil light reflex to measure the rod, cone, and melanopsin mediated pupil responses in humans and animals. Recently, we have extended our measurements to recording the EMG of the eye's squinting muscles and skin conductance in response to increasing intensities of red and blue light to objectively characterize photosensitivity in patients. Clinically, I also diagnose and work with patients and veterans with photophobia and headache following TBI. I have been collaborating with colleagues over the last few years on light mediated responses of the visual system. I also have a great deal of clinical expertise in photophobia and testing of visual function, including the pupil, besides my research and translational interests.

Center, Program and Institute Affiliations

Carver Family Center for Macular Degeneration
Fraternal Order of Eagles Diabetes Research Center
Institute for Clinical and Translational Science

Selected Publications

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Chen J, Costello F, Kardon R.  Sex disparities in neuro-ophthalmologic disorders.  Current eye research.  2015 February 1. 40(2):247-65.

Dutca L, Stasheff S, Hedberg-Buenz A, Rudd D, Batra N, Blodi F, Yorek M, Yin T, Shankar M, Herlein J, Naidoo J, Morlock L, Williams N, Kardon R, Anderson M, Pieper A, Harper M.  Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243.  Investigative ophthalmology & visual science.  2014 December 2. 55(12):8330-41.

Chen J, Kardon R, Longmuir R.  Diagnostic features of retinal nerve fiber layer rotation in skew deviation using optical coherence tomography.  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.  2014 December 1. 34(4):389-92.

Meier P, Maeder P, Kardon R, Borruat F.  Homonymous Ganglion Cell Layer Thinning After Isolated Occipital Lesion: Macular OCT Demonstrates Transsynaptic Retrograde Retinal Degeneration.  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.  2014 November 6. 

Kuburas A, Thompson S, Artemyev N, Kardon R, Russo A.  Photophobia and abnormally sustained pupil responses in a mouse model of bradyopsia.  Investigative ophthalmology & visual science.  2014 September 25. 55(10):6878-85.

Antony B, Abràmoff M, Harper M, Jeong W, Sohn E, Kwon Y, Kardon R, Garvin M.  A combined machine-learning and graph-based framework for the segmentation of retinal surfaces in SD-OCT volumes.  Biomed Opt Express.  2013 November. 4(12):2712-2728.

Kawasaki A, Crippa S, Kardon R, Leon L, Hamel C.  Characterization of Pupil Responses to Blue and Red Light Stimuli in Autosomal Dominant Retinitis Pigmentosa due to NR2E3 Mutation..  Investigative ophthalmology & visual science.  2012 September. 53(9):5562-9.

Mohan K, Harper M, Kecova H, Ye E, Lazic T, Sakaguchi D, Kardon R, Grozdanic S.  Characterization of structure and function of the mouse retina using pattern electroretinography, pupil light reflex, and optical coherence tomography..  Veterinary ophthalmology.  2012 September. 15 Suppl 2:94-104.

Thurtell M, Kardon R.  Recovery of vision from no light perception in giant cell arteritis..  Archives of ophthalmology.  2012 August. 130(8):1080-2.

Tang L, Kardon R, Wang J, Garvin M, Lee K, Abramoff M.  Quantitative evaluation of papilledema from stereoscopic color fundus photographs..  Investigative ophthalmology & visual science.  2012 July. 53(8):4490-7.

Date Last Modified: 10/13/2016 - 12:41:51