Ophthalmology And Visual Sciences

Wallace L. Alward, MD


Frederick C. Blodi Chair in Ophthalmology
Vice-Chair, Ophthalmology
Director, Glaucoma Service
Professor of Ophthalmology and Visual Sciences

Contact Information

Primary Office: 11190C  PFP
Iowa City, IA 52242
Phone: 319-356-2228

Email: wallace-alward@uiowa.edu
Web: Iowa Glaucoma Center
Web: Gonioscopy.org
Web: Iowa Glaucoma Curriculum
Web: UI Clinical Profile


AB, Biology, Kenyon College
MD, Medicine, Ohio State University

Internship, General Surgery, University Hospitals of Pittsburgh
Residency, Chief Resident, Ophthalmology, University of Louisville
Residency, Ophthalmology, University of Louisville
Fellowship, Glaucoma, Bascom Palmer Eye Institute, University of Miami

Licensure and Certifications

State of Florida Medical License (inactive)
State of Kentucky Medical License (inactive)
State of Alaska Medical License (Inactive)
NBME Diplomate, National Board of Medical Examiners
ABO Certification, American Board of Ophthalmology

Research Summary

Dr. Alward is primarily a glaucoma clinician. His areas of research interest include pigmentary glaucoma, combined glaucoma and cataract surgery, normal tension glaucoma, and gonioscopy. The major focus of his research over the last many years has been the molecular genetics of glaucoma. In collaboration with Edwin Stone and Val Sheffield, Dr. Alward was part of the team that described the first gene for primary open angle glaucoma. He was involved in the the discovery of the myocilin gene for primary open angle glaucoma, the PITX2 and FOXC1 genes for Axenfeld-Rieger syndrome and the TBK1 gene for normal tension glaucoma.

Center, Program and Institute Affiliations

Carver Family Center for Macular Degeneration
Stephen A. Wynn Institute for Vision Research

Selected Publications

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Ahram D, Alward W, Kuehn M.  The genetic mechanisms of primary angle closure glaucoma.  Eye (London, England).  2015 October 1. 29(10):1251-9.

Alward W.  Gonioscopy.org – A website to teach gonioscopy through the use of videography.  2015. 

Khorram D, Choi M, Roos B, Stone E, Kopel T, Allen R, Alward W, Scheetz T, Fingert J.  Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos.  Molecular vision.  2015 January 1. 21:1017-23.

Risma T, Alward W.  Successful Long-term Management of Iris Flocculi and Miosis in a Patient With a Strong Family History of Thoracic Aortic Aneurysms and Dissections Associated With an MYH11 Mutation.  JAMA ophthalmology.  2014. 132(6):778-80.

Seo S, Solivan-Timple F, Roos B, Robin A, Stone E, Young Y, Alward W, Fingert J.  Identification of proteins that interact with TANK binding kinase 1 and testing for mutations associated with glaucoma.  Curr Eye Res.  2013 February. 38(2):310-5.

Scheetz T, Fingert J, Wang K, Kuehn M, Knudtson K, Alward W, Boldt H, Russell S, Folk J, Casavant T, Braun T, Clark A, Stone E, Sheffield V.  A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci.  PLoS One.  2013. 8(3):e58657.

Wandling G, Rauen M, Goins K, Kitzmann A, Sutphin J, Kwon Y, Alward W, Wagoner M.  Glaucoma therapy escalation in eyes with pseudophakic corneal edema after penetrating keratoplasty and Descemet's stripping automated endothelial keratoplasty.  International ophthalmology.  2012 February. 32(1):14-Sep.

Mao M, Solivan-Timpe F, Roos B, Mullins R, Oetting T, Kwon Y, Brzeskiewicz P, Stone E, Alward W, Anderson M, Fingert J.  Localization of SH3PXD2B in human eyes and detection of rare variants in patients with anterior segment diseases and glaucoma.  Molecular vision.  2012. 18:705-13.

Tang L, Garvin M, Lee K, Alward W, Kwon Y, Abramoff M.  Robust multiscale stereo matching from fundus images with radiometric differences.  IEEE transactions on pattern analysis and machine intelligence.  2011 November. 33(11):2245-58.

Fingert J, Robin A, Stone J, Roos B, Davis L, Scheetz T, Bennett S, Wassink T, Kwon Y, Alward W, Mullins R, Sheffield V, Stone E.  Copy number variations on chromosome 12q14 in patients with normal tension glaucoma.  Human molecular genetics.  2011 June. 20(12):2482-94.

Date Last Modified: 10/13/2016 - 12:33:17