Ophthalmology And Visual Sciences

Arlene V. Drack, MD


Ronald V. Keech, MD, Associate Professor in Ophthalmic Genetics
Director, Pediatric Electroretinogram Service
Associate Professor of Ophthalmology and Visual Sciences
Associate Professor of Pediatrics

Contact Information

Office: 11290-C PFP
Iowa City, IA 52242
Phone: 319-356-0382

Lab: 4111  MERF
Iowa City, IA 52242
Phone: 319-353-5507

Email: arlene-drack@uiowa.edu
Web: Watch profile video
Web: Dr Drack's Lab site (patient and research information)
Web: UI Clinical Profile


BS, Biology / Philosophy, University of Scranton
MD, Medicine, The Pennsylvania State University College of Medicine

Fellowship, ITT International Fellow, Immunology, Det Norske Radiumhospitalet, University of Oslo
Internship, Transitional Internship, Georgetown University Medical Center
Fellowship, Ophthalmic Genetics, Wilmer Institute, Johns Hopkins University
Residency, Ophthalmology, Georgetown University Medical Center
Fellowship, Pediatric Ophthalmology and Strabismus, University of Iowa, Department of Ophthalmology
Fellowship, Molecular Ophthalmic Genetics, University of Iowa

Licensure and Certifications

Medical License, Iowa Board of Medicine
Medical License (inactive), Colorado Board of Medical Examiners
Medical License (inactive), Georgia Composite Medical Board
ABO Certification, American Board of Ophthalmology
NBME Diplomate, National Board of Medical Examiners

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Genetics
Interdisciplinary Graduate Program in Neuroscience

Research Summary

Arlene V. Drack, M.D. is a clinician scientist specializing in juvenile inherited eye diseases. She is the inaugural Ronald V. Keech Associate Professor in Pediatric Ophthalmic Genetics at the University of Iowa Department of Ophthalmology and Visual Sciences. Her research focuses on inherited eye diseases that affect children, particularly in the development of novel treatments. She is experienced in subretinal injection of molecules to treat mouse models of retinal degeneration, as well as participating in human trials for retinal disorders. She co-directs both the clinical and rodent electroretinogram services at the University of Iowa. Her clinical practice includes the full scope of pediatric ophthalmology and strabismus, in addition to running specialized genetic eye disease clinics.

Center, Program and Institute Affiliations

John and Marcia Carver Nonprofit Genetic Testing Laboratory
Stephen A. Wynn Institute for Vision Research

Selected Publications

Show All

Wiley L, Burnight E, Drack A, Banach B, Ochoa D, Cranston C, Madumba R, East J, Mullins R, Stone E, Tucker B.  Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal Degeneration..  Human gene therapy.  2016 July 11. 

Nielsen A, Drack A, Ostergaard J.  Cataract and glaucoma development in juvenile neuronal ceroid lipofuscinosis (Batten disease).  Ophthalmic Genet.  2015. 36(1):39-42.

Whitmore S, Sohn E, Chirco K, Drack A, Stone E, Tucker B, Mullins R.  Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy.  Prog Retin Eye Res.  2015. 45C:1-29.

Wiley L, Burnight E, Songstad A, Drack A, Mullins R, Stone E, Tucker B.  Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases.  Prog Retin Eye Res.  2015. 44:15-35.

Stunkel M, Bhattarai S, Kemerley A, Stone E, Wang K, Mullins R, Drack A.  Vitritis in pediatric genetic retinal disorders.  Ophthalmology.  2015. 122(1):192-9.

Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhange Q, Drack A, Stone E, Sheffield V.  BBS mutations modify phenotypic expression of CEP290-related ciliopathies.  Hum Mol Genet.  2014. 23(1):40-51.

Shubert C, Pryds A, Zeng S, Xie Y, Bailey , Freund K, Spaide R, Merriam J, Barbazetto I, Slakter J, Chang S, Munch I, Drack A, Hernandez J, Yzer S, Merriam J, Linneberg A, Larsen M, Yannuzzi L, Mullins R, Allikmets R.  Cadherin 5 is Regulated by Corticosteroids and Associated with Central Serous Chorioretinopathy.  Hum Mutat.  2014. 35(7):859-67.

Nielsen A, Drack A, Ostergaard J.  Cataract and Glaucoma Development in Juvenile Neuronal Ceroid Lipofuscinosis (Batten Disease).  Ophthalmic Genet.  2014. 

Whitmore S, Wagner A, DeLuca A, Drack A, Stone E, Tucker B, Zeng S, Braun T, Mullins R, Scheetz T.  Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq.  Exp Eye Res.  2014. 129:93-106.

McAnany J, Genead M, Walia S, Drack A, Stone E, Koenekoop R, Traboulsi E, Smith A, Weleber R, Jacobson S, Fishman G.  Visual Acuity Changes in Patients With Leber Congenital Amaurosis and Mutations in CEP290..  JAMA Ophthalmol. .  2013 February 1. 131(2):178-82.

Date Last Modified: 10/13/2016 - 12:35:58