Nandakumar Narayanan, MD, PhD


Specialty: Parkinson's Disease
Assistant Director: Clinical Neuroscientist Training Program in Neurology
Assistant Director: Residency Program in Neurology
Assistant Professor of Neurology

Contact Information

Primary Office: 1336 PBDB
Iowa City, IA 52242
Phone: 319-356-4757

Web: Narayanan Laboratory


BA, Human Biology, Stanford University
MD, Medicine, Yale University
PhD, Neuroscience, Yale University

Internship, Medicine, Hospital of St. Raphael
Residency, Neurology, Yale Medical School
Post Doctorate, Yale Medical School

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Neuroscience

Research Summary

The specific problem we are interested is cognitive dysfunction in Parkinsons disease. Our current research focuses on the influence of dopamine on prefrontal networks controlling cognitive behaviors such as timing and performance monitoring. We combine ensemble recording from populations of neurons in awake, behaving animals with specific manipulations using techniques such as optogenetic stimulation, targeted pharmacology, or selective genetic disruption with RNA interference. We hope to identify new treatment strategies that can be translated to a clinical setting.

Center, Program and Institute Affiliations

Aging Mind and Brain Initiative

Selected Publications

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Fattahi P, Sheriff F, Narayanan N, Greer D, Schindler J.  Thrombolysis for acute stroke in patients with vasculitis: case report and literature discussion..  Clinical neurology and neurosurgery.  2013 March. 115(3):351-3.

Narayanan N, Land B, Solder J, Deisseroth K, DiLeone R.  Prefrontal D1 dopamine signaling is required for temporal control..  Proceedings of the National Academy of Sciences of the United States of America.  2012 December. 109(50):20726-31.

Narayanan N, Sheriff F, Boyce J.  Teaching NeuroImages: CNS actinomycosis in an immunocompetent patient..  Neurology.  2012 September. 79(10):e85.

Salardini A, Narayanan N, Arora J, Constable T, Jabbari B.  Ipsilateral synkinesia involves the supplementary motor area..  Neuroscience letters.  2012 August. 523(2):135-8.

Prabhakaran V, Rypma B, Narayanan N, Meier T, Austin B, Nair V, Naing L, Thomas L, Gabrieli J.  Capacity-speed relationships in prefrontal cortex..  PloS one.  2011. 6(11):e27504.

Sears R, Liu R, Narayanan N, Sharf R, Yeckel M, Laubach M, Aghajanian G, DiLeone R.  Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  2010 June. 30(24):8263-73.

Narayanan N, Guarnieri D, DiLeone R.  Metabolic hormones, dopamine circuits, and feeding..  Frontiers in neuroendocrinology.  2010 January. 31(1):104-12.

Smith N, Narayanan N, Laubach M.  Past performance is indicative of future returns..  Neuron.  2009 July. 63(2):146-8.

Narayanan N, Laubach M.  Methods for studying functional interactions among neuronal populations..  Methods in molecular biology (Clifton, N.J.).  2009. 489:135-65.

Narayanan N, Laubach M.  Neuronal correlates of post-error slowing in the rat dorsomedial prefrontal cortex..  Journal of neurophysiology.  2008 July. 100(1):520-5.

Date Last Modified: 09/23/2016 - 15:07:07