Internal Medicine

Jason H. Barker, MD


Associate Professor of Internal Medicine  - Infectious Diseases

Contact Information

Primary Office: E104 MTF
Iowa City, IA 52242
Phone: 319-335-4594

Web: Inflammation Program


MD, Baylor College of Medicine

Residency, Internal Medicine, University of Texas Southwestern
Fellowship, Infectious Diseases, University of Iowa Hospitals and Clinics

Licensure and Certifications

Infectious Diseases, American Board of Medicine

Research Summary

Dr. Barker's research focuses on interactions between the immune system and lipopolysaccharide, and important component of man medically important bacteria. In particular, he is interested in understanding how Francisella tularensis alters the structure of its lipopolysaccharide during growth in phagocytes. In addition, he is interested in how lipopolysaccharide interacts with inflammatory caspases 4 and 11.

Center, Program and Institute Affiliations

Inflammation Program

Selected Publications

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Yao C, Dixit U, Barker J, Teesch L, Love-Homan L, Donelson J, Wilson M.  Attenuation of Leishmania metacyclic promastigotes by sterol depletion.  Infection and Immunity.  2013 July 1. 81(7):2507-17.

Schwartz J, Barker J, Kaufman J, Fayram D, Allen L.  Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespan.  J. Immunol..  2012 April. 188(7):3351-63.

Barker J, Luby J, Dalley A, Bartek W, Burns D, Erdman D.  Fatal type 3 adenoviral pneumonia in immunocompetent adult identical twins.  Clin. Infect. Dis..  2003 November 15. 37(10):e142-6.

Date Last Modified: 06/06/2016 - 13:17:48