Yi, Zuoan

Zuoan Yi

Postdoctoral Research Fellow
Address: 2219 MERF
Phone: (319) 335-7816
Email: zuoan-yi@uiowa.edu

Mentor: Gail Bishop, PhD

PhD Institution: Chinese Center for Disease Control and Prevention

Research Description

I am interested in understanding the role of TRAF3 in T cell immunology.


Yi Z, Li L, Garland A, He Q, Wang H, Katz JD, Tisch R, Wang B. IFN-γ receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells. Eur J Immunol. 2012 Aug;42(8):2010-8.

Yi Z, Diz R, Martin AJ, Morillon YM, Kline DE, Li L, Wang B, Tisch R. Long-term remission of diabetes in NOD mice is induced by nondepleting anti-CD4 and anti-CD8 antibodies. Diabetes. 2012 Nov;61(11):2871-80.

Hildebrand JM, Yi Z, Buchta CM, Poovassery J, Stunz LL, Bishop GA. Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions. Immunol Rev. 2011 Nov;244(1):55-74. Review.

Li L, He Q, Garland A, Yi Z, Aybar LT, Kepler TB, Frelinger JA, Wang B, Tisch R. Beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct. J Immunol. 2009 Dec 1;183(11):7585-91.

Li L, Yi Z, Wang B, Tisch R. Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination. J Immunol. 2009 Oct 1;183(7):4809-16.

Yi Z, Li L, Matsushima GK, Earp HS, Wang B, Tisch R. A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells. Blood. 2009 Oct 8;114(15):3191-8.

Pang S, Zhang L, Wang H, Yi Z, Li L, Gao L, Zhao J, Tisch R, Katz JD, Wang B.CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. Eur J Immunol. 2009 Oct;39(10):2716-24.

Wallet MA, Flores RR, Wang Y, Yi Z, Kroger CJ, Mathews CE, Earp HS, Matsushima G, Wang B, Tisch R. MerTK regulates thymic selection of autoreactive T cells. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4810-5.

Li L, Yi Z, Tisch R, Wang B. Immunotherapy of type 1 diabetes. Arch Immunol Ther Exp (Warsz). 2008 Jul-Aug;56(4):227-36.

Wallet MA, Sen P, Flores RR, Wang Y, Yi Z, Huang Y, Mathews CE, Earp HS, Matsushima G, Wang B, Tisch R. MerTK is required for apoptotic cell-induced T cell tolerance. J Exp Med. 2008 Jan 21;205(1):219-32.

Sen P, Wallet MA, Yi Z, Huang Y, Henderson M, Mathews CE, Earp HS, Matsushima G, Baldwin AS Jr, Tisch RM. Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells. Blood. 2007 Jan 15;109(2):653-60.