Psychiatry

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    Current Research

    The following is a list of our current research initiatives organized by investigator's last name.

    Initiative Investigator
    - Brain Imaging in Major Psychoses: Examining Structural and Functional Connectivity
    - Effects of Paliperidone Palmitate vs Oral Atypicals on Clinical Outcome and sMR Measures in First Episode Patients: A Randomized Clinical Trial
    - Identifying the Brain Mechanisms Underlying Paranoia
    - Iowa Study of Creative Genius
    - Relapse Prevention and Progressive Brain Change in Schizophrenia     		Nancy Andreasen, MD, PhD
    - Iowa Consortium for Substance Abuse and Evaluation Stephan Arndt, PhD
    - Follow-up Study of Addictions and Co‐occurring Disorders in Older Adults
    - Seroquel XR for the Management of Borderline Personality Disorder
    - Treatment of Male and Female Incarcerated Offenders with Borderline Personality Disorder in the Iowa Prison System Using the STEPPS Program     		Donald Black, MD
    - Postnatal Yoga for Women's Health Melissa Buttner
    - Counteracting Risperidone‐Induced Hyperprolactinemia in Youths
    - Selective Serotonin Reuptake Inhibitors (SSRIs) and Bone Mineralization in Adolescents and Young Adults     		Chadi Calarge, MD
    - Cytokines, PUFA Tissue Concentrations and Treatment Selection in Antenatal MDD
    - National Network of Depression Centers (NNDC): Common Assessment Program
    - Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder     		William Coryell, MD
    - ACT on Health Lilian Dindo, PhD
    - Creatine Safety, Tolerability, Efficacy in Huntington's Disease Eric Epping, MD, PhD
    - Antipsychotics and Blood Vessel Function
    - Mood and Affect Registry    		 Jess Fiedorowicz, MD
    - Iowa Consortium for Mental Health Michael Flaum, MD
    Shizhong Han Laboratory
    - Enhancing Gene Discovery of Psychiatric Disorders Using Endophenotypes
    - Integrated System Genetic Approaches for Psychiatric Disorders
    - Using Prior Information to Boost the Power of Next-Generation Genetic Studies
    - Linkage, Candidate Genes and Other Research Interests     		Shizhong Han, PhD
    - High‐throughput Combined Assay of Multiplex Serum Biomarkers for Schizophrenia Beng Choon Ho, MD
    - National Alliance for Medical Image Computing (NAMIC) Hans Johnson, PhD
    - Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury Ricardo Jorge, MD
    - Project LAUNCH Robin Kopelman, MD, MPH
    - Collaborative Study on the Genetics of Alcoholism (COGA)
    - Collaborative Genomic Studies of Tourette Disorder     		Samuel Kuperman, MD
    - Defining the Neural Circuitry Underlying Food Reward and Consumption of Stress-induced "Comfort Foods"
    - Identifying the Molecular and Cellular Basis Eating Disorders    		 Michael Lutter, MD, PhD
    - Anorexia Nervosa: Regional Brain Abnormalities and Relationship to Outcome
    - Mapping Anterior Cingulate Volume Trajectory in Schizophrenia and Healthy Comparison Subject Brains     		Laurie McCormick, MD
    - ACLAIMS (A Comparison of Long-Acting Injectiable Medications for Schizophrenia)
    - Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Persistent, Predominant Negative Symptoms
    - Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Sub-Optimally Controlled Symptoms    		 Del Miller, MD, PharmD
    - Vascular Function, Cognition and Brain MRI in Atherosclerotic Vascular Disease David Moser, PhD
    - Brain Structure, Function, and Growth in Children with Huntington's Disease
    - Brain Structure and Function in Children at Risk for Huntington's Disease
    - Brain Structure and Function in Children with Oral Clefts    		 Peggy Nopoulos, MD
    Cognitive Brain Development Laboratory
    - Marijuana Use and Schizophrenia
    - Brain Development in Adolescents with Genetics Risk Factors for Alcoholism    		 Daniel O'Leary, PhD
    - University of Iowa Huntington's Disease Society of America Center of Excellence Jane Paulsen, PhD
    - The Effects of Smoking on DNA Methylation in Primary Human Lymphocyte
    - Examination of Genetic and GxE Effects in the Family and Community Health Studies
    - Factors Influencing the Health Behaviors of Young African American Adults
    - Gene Array Expression Biomarkers from Whole Blood to Diagnose Schizophrenia and Bipolar Disorder
    - A Transdiciplinary Center Focused on Rural African American Families    		 Robert Philibert, MD, PhD
    - A Genome‐wide Approach to the Epigenetics of Stress and Depression
    - Whole Exome Sequencing in Bipolar Disorder    		 James Potash, MD, MPH
    - Alzheimer’s Disease Neuroimaging Initiative 2 (ADNI-2)
    - Potential Protection from Alzheimer’s-Related Brain Changes Among Persons Treated for Paranoia and Schizophrenia
    - A Randomized, Double-Blind, Placebo-Controlled, Two Dose-Arm, Parallel Study of the Safety and Effectiveness of Immune Globulin Intravenous (Human), 10 Percent (IGIV, 10 Percent) for the Treatment of Mild-to-Moderate Alzheimer's Disease    		 Susan Schultz, MD
    - Interpersonal Psychotherapy Institute Scott Stuart, MD
    - Parent-Child Interaction Therapy Beth Troutman, PhD
    Cognitive Brain Development Laboratory
    - Attentional Capacity in Adolescence    		 Jatin Vaidya, PhD
    - Combined Illness Management and Psychotherapy in Treating Depressed Elders
    - My HealtheVet Project: Blue Button Feature Evaluation
    - Training: the Conduct of Psychosocial Care Intervention    		 Carolyn Turvey, PhD
    - A Family-Genetic Study of Language in Autism Thomas Wassink, MD
    - Brain pH and Acid Sensing in Depression Related Behavior
    - Modeling CO2‐Evoked Fear in Mice: Role of Acid‐Sensing Ion Channels
    - Regulation of Cerebral Blood Flow by Acid-Sensing Ion Channels (ASICs)    		 John Wemmie, MD, PhD
    - Attempted Suicide Candidate Gene Resequencing Virginia Willour, PhD