Doris Duke Clinical Research Fellowship Program

University of Iowa Roy J. and Lucille A. Carver College of Medicine

Mentors

 

Scholars in the University of Iowa's Doris Duke Clinical Research Fellowship Program have the opportunity to work with outstanding clinical research faculty.

The list of faculty on this page
shows only a small sample of potential mentors. Any research faculty at the University of Iowa
is a potential mentor.

To view more potential mentors, search by department on the University of Iowa's A to Z search page.

 

Anesthesia

Dr. Campos' research focuses on thoracic and cardiac anesthesia, lung separation techniques, Congenital heart disease

Dr. Hata's research interests include the alteration of fibronectin on tracheal epithelium during critical illness and echocardiography assessment of left ventricular preload during critical illness.

Dr. Hindman's research interests include Perioperative central nervous system injury (prevention & treatment) and cervical spine dynamics during endotracheal intubation

Dr. Todd's current research projects include studying intraoperative hypothermia during aneurysm surgery, the movement of the cervical spine during endotracheal intubation and examining the impact of various stabilization methods. He is also examining the effects of hemodilution and hypoxia on cerebral blood flow and on the relative activity of various endothelial flow mediators.

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Cardiology

Dr. Abboud's research interests are directed toward the neural regulation of the circulation. Specific studies examine the cellular and molecular mechanisms of mechanical activation of baroreceptor neurons and the role of stretch-activated ion channels in the generation of baroreceptor nerve activity in isolated neurons and in transgenic mice.

Dr. Chapleau's research focuses on mechanisms of baroreceptor activation and factors determining sympathetic nerve activity in normal and pathologic states including hypertension, atherosclerosis and aging. Experimental approaches include studies in genetically modified mice and gene transfer using viral vectors.

Dr. Heistad's clinical interests include general cardiology. His research interests focus on gene transfer to blood vessels, cerebral circulation, and vascular biology of atherosclerosis, hypertension, and diabetes.

Dr. Mark's research interests focus on sympathetic and cardiovascular actions of  insulin, leptin, and neuropeptides in mechanisms of obesity-induced hypertension.

Dr. Snyder's research interests include sodium channel structure and function.  He is currently investigating the mechanism of dysfunction of the epithelial Na + channel (ENaC) in hypertension and the structure of the channel pore of ENaC.

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Dermatology

Dr. Fairley's research interests are blistering Diseases of the skin, epidermal cell physiology, and Dermatology education

Epidemiology

Dr. Torner's research focuses on the design of clinical trials, analysis of clinical trials, analysis of prognostic factors, neuroepidemiology, meta-analysis, pharmacoepidemiology of adverse experiences, cerebrovascular disease epidemiology (risk factors and prognostic factors), cardiovascular epidemiology, statistical methods for observational studies, injury epidemiology/acute care, prostate cancer, and telemedicine.

Dr. Wallace's current research interests include the epidemiology of aging, cancer epidemiology and control, clinical preventive medicine, survey research, and the prevention of disability

Family Medicine

Dr. Levy's research interests focus on women's health, osteoporosis, colorectal cancer screening, and health promotion

Gastroenterology & Hepatology

Dr. Elliott's research interest focuses on the mechanisms that control inflammatory reactions. His studies include the liver granulomas that develop in murine schistosomiasis; the role of the neuropeptide somatostatin in the regulation of the granulomatous response; and soluble mediators released by granuloma cells that affect inflammatory responses. He employs the ELISA assays of lymphokine production, cellular cloning, Northern blot analysis of granuloma mRNA, reverse transcription PCR or granuloma lymphocyte mRNA, RNASE protection assays, and molecular cloning.  His key interests are immunology, immunoregulation, granulomatous inflammation, schistosomiasis, and inflammatory bowel diseases, lymphokines, T cell receptor.

Bruce Luxon, MD, PhD
Professor & Chair
Division of Gastroenterology-Hepatology
Department of Internal Medicine
2007-08 mentor to Anne Wilson

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Health Management & Policy

Dr. Schneider's research interests include market structure, cost analysis, regulation, managed care, economics of organizations, and process Innovation

Dr. Rosenthal's clinical interests include inpatient and consultative general internal medicine. His research interests include the assessment o health care quality and provider performance, organizational determinants of patient outcomes, patient safety, and the role of the Department of Veterans Affairs in the US health care delivery system.

Hematology, Oncology and Blood &  Marrow Transplantation

Dr. Weiner's research focuses on the immunotherapy of lymphoma and leukemia including the development and evaluation of genetically modified monoclonal antibody constructs and development of novel immune adjuvants for cancer immunization.

Dr Yee's research interests focus on studying the biology and genetics of pancreatic development and cancer.

Infectious Diseases

Dr. Wilson's research interests focus on visceral leishmaniasis, a disease prevalent in many underdeveloped nations. Her studies address several aspects of the pathogenesis of this disease: first, the molecular determinants governing the expression of gp63, a surface protease important for parasite virulence; second, virulence characteristics of Leishmania including their utilization of iron and their resistance to toxic oxidants; third, the cell-mediated immune response to Leishmania and recombinant antigens responsible for eliciting these responses.

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Neurology

The organizing theme of Dr. Denburg's empirical work is the study of developmental changes in cognition. Her main line of research involves the study of aging cognition.She is particularly interested in how attention and emotion impact cognitive functioning, such as memory and executive functioning, in both healthy and clinical populations of older adults. Utilizing an experimental gambling task that is designed to mimic real-world decision-making, she found that a sizeable subset of older adults failed to demonstrate appropriate risk-aversiveness, and instead continued to select from the disadvantageous decks in a manner reminiscent of patients with bilateral ventromedial prefrontal lobe lesions.

Dr. Grabowski's research interests are 1) cognitive neuroscience, focusing on applications of functional neuroimaging to investigation of the neural systems supporting lexical processing, emotion, and decision making; 2) physiological correlates of defective cognition, especially aphasia; 3) statistical analyses for functional brain images; development of statistical methods for analyzing brain activation images from individual brain-damaged subjects; 4) investigation of lexical retrieval in normal and brain-damaged populations with position emission tomography; and 5) Investigation of neural correlates of emotional states and decision making with position emission tomography

Some of Dr. Talman's research interests are the central control of circulation, integration of cardiovascular and noncardiovascular reflexes, neurogenic hypertension, the baroreceptor reflex in health and disease, central neurotransmitters, central neural regulation of cerebral blood flow, and the role of central excitatory amino acid receptors in the baroreceptor reflex

Neurosurgery

Dr. Howard directs the University of Iowa's Human Brain Research Laboratory (HBRL). The overall aim of research in the HBRL is to gain new knowledge on the neural mechanisms in the human brain that underlie sensory, perceptual and cognitive processes related to hearing, speech, language and emotional behavior.

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Opthalmology & Visual Sciences

Orthopaedic Surgery

Dr. Albright researches the detection and diagnosis of sports-related injuries

Dr. Buckwalter's principle interests include osteoarthritis, musculoskeletal oncology, sports medicine, trauma, and reconstructive surgery

Dr. Morcuende's research focuses on molecular genetics of musculoskeletal disorders, pediatric tumors, pediatric hip, foot, and spine disorders, and evidence-based outcomes in pediatric orthopaedics.

Dr. Weinstein's specialites include pediatric orthopaedic surgery and spinal deformity.

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Otolargnology

Dr. Canady's is currently researching growth factor analysis in wound healing, physiology and movement mechanics of the soft palate, mechanisms of scar formation and regulation, and wound healing in both post natal and fetal models, and particularly how modified mechanisms of wound healing can be applied to craniofacial surgery

Dr. Hansen is currently researching the regulation of auditory neuron axon growth by activity and the role of ErbB receptor signaling in vestibular schwannomas.

Dr. Lee's current research focuses on HPV infection of airway epithelia.

Dr. Manaligod is currently researching the molecular genetics of laryngeal dysfunction and disease and the molecular genetics of ear development in xenopus laevis

Dr. Smith's current research includes Hereditary deafness: branchio-oto-renal syndrome, usher syndrome, pendred syndrome, deaf mouse mutants, molecular genetic studies of archival temporal bones, and non-syndromic hearing loss.

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Pathology

Dr. Cook's research interests in the immunology of alcoholism, including basic processes such as lymphocyte activation and adhesion, emigration, neutrophil and monocyte adhesion, and cytokine-mediated lymphocyte differentiation.

Dr. Doern's research focuses are epidemiology, mechanisms and laboratory detection of antibiotic resistance particularly among out-patient bacterial pathogens, the clinical impact of laboratory testing and the development and evaluation of novel diagnostic methods in clinical microbiology.

Dr. Knudson's research interest revolves around the regulation of Programmed Cell Death (PCD) by the Bc1-2 Family of Proteins. Aberrant regulation of PCD results in diverse defects ranging from cancer to infertility to neurodegeneration. The focus of the lab is to understand the biochemical basis for Bc1-2 activity and study it's role in development and disease.

Dr. Moore's research focus is Muscular Dystrophy

Dr. Waldschmidt's research interests are B cell development, B cell subsets, Germinal center reaction, Bone marrow transplantation, Effect of ethanol on B cell function.

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Pediatrics

Dr. McCray's three main research interests are (1) Developmental regulation of ion transport in the lung. (2) Gene transfer to developing lung. Focusing on integrating viral vectors. (3) Innate immune mechanisms in the lung. Current focus on defensin expression.

Dr. Murray's research includes identifying genetic and environmental components of craniofacial birth defects, with a special emphasis on cleft lip and palate and the development of clinical trials of vitamins to prevent birth defects in developing countries.

Dr. Sheffield's research interests are in identifying genes which cause human genetic diseases, specifically hereditary eye diseases including glaucoma, macular dystrophies, and retinis pigmentosa. He also researches congenital heart defects and deafness and the Human Geno.

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Pharmacology

Dr. Haynes' research interests include studies of the effects of homocysteine, diabetes, hypertension and hyperlipidemia on endothelial function in humans. He is also interested in the cardiovascular and autonomic effects of obesity and has a particular interest in vascular medicine, focusing on prevention and regression of atherosclerosis through management of cardiovascular risk factors.

Dr. Hohl's research interests focus on understanding the interactions between mevalonic acid and cholesterol biosynthesis and the proliferation of acute myeloid leukemia cells.

Dr. Lill's research interests include targeting activated growth factor receptors for downregulation and degradation

Physiology & Biophysics

Dr. Snyder's research interests include sodium channel structure and function.  He is currently investigating the mechanism of dysfunction of the epithelial Na + channel (ENaC) in hypertension and the structure of the channel pore of ENaC.

Dr. Russo's research interests center on how neuronal gene expression is regulated in response to changes in the cellular environment. The long-term goal is to develop effective gene therapy and diagnostic strategies.

Psychiatry

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Pulmonary

Dr. Hunninghake's clinical and research interests include the areas of sarcoidosis, asthma, occupational lung disease, and interstitial lung disease. Dr. Hunninghake's basic studies emphasize molecular and cellular biology, virology and second messenger studies.

Dr. Kline's research focuses on modulation of airway inflammation in asthma. Using murine models, he is investigating how DNA containing CpG motifs and other innate immune stimuli can prevent and reverse eosinophilic airway inflammation, bronchial hyperresponsiveness, and airway remodeling.

Dr. McLennan's clinical research includes studies of new applications for fiber optic bronchoscopy.

Dr. Zabner's research interests are in gene transfer to human airway epithelia in particular to develop gene therapy for cystic fibrosis. Dr. Zabner also has an interest in the fluid composition of the airway surface liquid, and how it affects innate immunity. His clinical interests are in cystic fibrosis and non-cystic fibrosis bronchiectasis.

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Radiology

Dr. Bennett's clinical and research interests are MRI of the spine in Olympic-level gymnasts, MRI of repetitive stress Injury of the Wrist, and the correlation of knee MRI in the setting of Acute MVA.

Dr. Fajardo's research focuses on breast imaging

Dr. Hoffman's research includes dynamic, volumetric physiologic imaging and image analysis and cardiopulmonary physiology.

Dr. Magnotta's current research is in diagnostic radiology.

Dr. van Beek's research includes functional lung imaging, including CT, proton MRI, hyperpolarized 3-Helium MRI and other novel technologies; diagnosis and managemetn of acute chronic pulmonary embolism; cardiac imaging using multiple modalities (including MRI and CT); lung cancer imaging (from CXR to CT, MRI and PET-CT); and the development of software tools for disease detection and quantification for multiple modalities.

Radiology Oncology

Dr. Bayouth's clinical research focuses on intensity modulated radiation therapy (IMRT) and image-guided radiotherapy (IGT).

Dr. Buatti's principle interests are in tumors of the central nervous system and treating tumors with optically-guidedradiotherapy.