Fig. 2 Proteasome-mediated proteotoxic stress induces nucleolar migration of RGS6 proteins. Confocal microscopic overlay pictures showing nucleolar migration of RGS6 splice forms following treatment with proteosomal inhibitor, MG132. COS-7 cells expressing EGFP-tagged RGS6 proteins were treated with 10 micromolar MG132. Green represents EGFP-tagged RGS6 proteins and red represents propidium iodide (PI)-stained nuclei.