The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Bupropion (Wellbutrin)
Order Code: BUPR
Order Form: A-1a Miscellaneous Request or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Serum
Collection Medium:
Red top tube
Alternate
Collection Media:
Green top tube (Na Heparin), Lavender top tube (EDTA)
Minimum:
Adult Preferred minimium:  2.5 mL serum, heparinized or EDTA plasma
Absolute Adult & Pediatric minimum: 1.5 mL serum, heparinized
  or EDTA plasma
Rejection Criteria:
Gel separator tubes
Delivery Instructions:
Deliver to laboratory within 1 hour of collection.
Analytic Time:
5 working days
Reference Range:
Therapeutic range:  50 - 100 ng/mL
Comments:
The therapeutic range is not well established. Patient response appears 
to improve with concentrations between 50 and 100 ng/mL. Levels below 
25 ng/mL may have no effect. Poor response and increased toxicity have 
been reported at concentrations above 100 ng/mL.
Methodology:
High Performance Liquid Chromatography
CPT Code:
82486

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Updated: 07/11/2008

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.