Specimen:

Urine

Collection Medium:

Minimum:

Collect second morning void or 24 hr urine.  Sample must be 
refrigerated during collection.  No preservative.
Adult preferred minimum: 1.0 ml
Adult absolute minimum 0.5 ml
Pediatric minimum: 0.5 ml

Rejection Criteria:

Specimens contaminated with blood or having extensive hemolysis.

Analytic Time:

4 working days

Reference Range:

Age                   Male                         Female
7-9 yrs       167-578 nM BCE/mM creatinine 201-626 nM BCE/mM creatinine
10-12 yrs     152-505 nM BCE/mM creatinine 173-728 nM BCE/mM creatinine
13-15 yrs     103-776 nM BCE/mM creatinine  38-515 nM BCE/mM creatinine
16-17 yrs      34-313 nM BCE/mM creatinine  20-144 nM BCE/mM creatinine
18 yrs & older  21-83 nM BCE/mM creatinine
Premenopausal                               17-94 nM BCE/mM creatinine
Postmenopausal                              26-124 nM BCE/mM creatinine

NTx Units = nM BCE/mM Creatinine
NTx = Cross-linked N-telopeptide of Type I Collagen
BCE = Bone collagen equivalent

A decrease of 30-40% from the NTx baseline after 3 months of therapy is 
a typical response to anti-resorptive therapy.

Comments:

For monitoring therapy, a baseline sample should be collected
prior to initiation of therapy.  Subsequent samples for
comparison should be collected at the same time of day as the
baseline sample.

Please print, complete and submit the Advance Beneficiary Notice 
(ABN) along with the Laboratory Requisition before shipping the 
specimen.

Methodology:

Chemiluminescent Immunoassay

CPT Code:

82523

See Additional Information:
Urine Tests Requiring no Preservatives