Specimen

Serum

Collection Medium:

Minimum:

Preferred minimum:  1 mL serum
Absolute minimum:  0.3 mL serum

Rejection Criteria:

No hemolysis, lipemia, gels or glass tubes.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Specimen
Instructions:

Do not submit specimens that have been heat treated.
Do not submit the sample in a glass tube.
Overnight fasting is preferred.

Analytic Time:

within 10 days

Reference Range:

Mannose-binding Lectin ng/mL
DEFICIENT: <100
NORMAL: >=100

Mannan-binding lectin (MBL) is a plasma collection (c-type lectin) and 
is considered an important component of the innate immune system. 
Clinical studies have used 50 or 100 ng/mL to define severe MBL 
deficiency. MBL is also known to activate the classical complement 
pathway through its binding to serine proteases MASP-2 and MASP-1. MBL 
deficiency has been associated with recurrent infections in children 6 
months to 17 months of age, during the time when the adaptive immune 
system (IgG Production) is not fully mature.

Methodology:

Enzyme Linked Immunosorbent Immunoassay

CPT Code:

83520