Specimen

Serum

Collection Medium:

Minimum:

Recommended minimum: 2 mL serum
Absolute minimum:  0.5 mL serum

Analytic Time:

2 working days (upon receipt)

Reference Range:

Asper A: Negative
Index: By report

Test
Limitations:

Negative results do not exclude the diagnosis of invasive 
aspergillosis.  A single positive test result (index equal to or 
greater than 0.5) should be clinically correlated by testing a separate 
serum specimen because many agents (e.g. food, antibiotics) may 
cross-react with the assay.  If invasive aspergillosis is suspected in 
high-risk patients, serial sampling is recommended.

The false positive rate is higher in children than in adults. (Cancer 
91:311, 2001; J.Clin Oncol 20:1898,2002; Mycosis 41:373,1998).

Methodology:

Enzyme Immunoassay

CPT Code:

87305