The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

Zonisamide (Zonegran)
Order Code: ZONI
Epic Lab Code: LAB504
Order Form: A-1a Miscellaneous Request or Epic Req 		  Commercial "Mail-out" Laboratory
6240 RCP
356-3527 
Specimen:
 
Serum or Plasma
Collection Medium:
Red top tube 


Alternate
Collection Media:


Lavender top tube (EDTA), Green top tube (Na Heparin), Light Green top 
tube (Lithium Heparin), Pink top tube (EDTA sprayed)


Minimum:


Preferred Minimum 1.5 mL serum or plasma
Absolute Minimum:  0.8 mL serum or plasma


Rejection Criteria:


Gel separator tubes


Delivery Instructions:


Submit specimen to laboratory as soon as possible after collection.


Analytic Time:


4 days


Reference Range:


Therapeutic Range not well established.


Test
Limitations:


The proposed therapeutic range for seizure control is  10-40 ug/ml.  
Concentrations that exceed 80 ug/ml may contribute to adverse effects.  
Pharmacokinetics varies widely, particularly with co-medications and/or 
compromised renal function.


Methodology:


Immunoassay


CPT Code:


80299




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Updated: 08/19/2008

Note: The information contained in this handbook is  
            for use by personnel of University of Iowa Health Care. 
            No other use is implied or intended.