• Past Seminar Speakers

    Spring 2014

    Pamela Hall, Department of Pharmaceutical Sciences, University of New Mexico
    Pharmacological disruption of agr quorum sensing in Staphylococcus aureus protects against skin and soft tissue infection

    David Weiss, Emory Vaccine Center, Emory University
    CRISPR/Cas-mediated endogenous gene regulation is required for bacterial innate immune evasion

    Kim Lewis, Department of Biology, Northeastern University
    Persisters and the quest for a biofilm-sterilizing antibiotic

    Christine Petersen, Department of Epidemiology, University of Iowa
    Lessons from a Tropical Disease in the Midwest

    Jenny Gumperz, Medical Microbiology & Immunology, University of Wisconsin-Madison
    Linking NKT cells to Inflammation

    Shan-Lu Liu, Molecular Microbiology & Immunology, University of Missouri
    New Cellular Factors Modulating Viral Infections

    S. Celeste Morley, Department of Pediatrics, Washington University School of Medicine in St Louis
    Immunodeficiency as a movement disorder: impaired immunity in mice deficient for L-plastin

    Robert Schleif, Department of Biology, Johns Hopkins University
    The Bottom Line on the Regulatory Protein AraC (240 Person-years of work)

    Dennis W. Metzger, Center for Immunology & Microbial Disease, Albany Medical College
    Influenza and Secondary Bacterial Pneumonia Mechanisms

    George A. O'Toole, Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth
    To Build a Biofilm

    Daniel Zurawski, Walter Reed Army Institute of Research
    Defining an appropriate strain and developing animal models to study Acinetobacter baumannii pathogenesis and novel antimicrobials

    Ekaterina Heldwein, Department of Molecular Biology & Microbiology, Tufts University
    Herpesviruses on the way out: what structures and biophysics can tell us

    Fall 2013

    John Kirby, Department of Microbiology, University of Iowa
    Chemosensory regulation of microbial communities

    William Goldman, Department of Microbiology & Immunology, University of North Carolina
    The Progression of Pneumonic Plague

    Craig Ellermeier, Department of Microbiology, University of Iowa
    A Bacterial Receptor for Lysozyme Controls σ Factor Activation and Lysozyme Resistance

    Wilmara Salgado-Pabón, Department of Microbiology, University of Iowa
    Molecular Pathogenesis of Staphylococcal Infective Endocarditis

    Steven McElroy, Department of Pediatrics, University of Iowa
    Untangling the Role of Bacteria in Development of Neonatal Necrotizing Enterocolitis 

    Keji Zhao, Laboratory of Epigenome Biology, National Heart Lung & Blood Institute
    Epigenetic regulation of T cell differentiation

    Erhard Bremer, Laboratory for Molecular Microbiology, University of Marburg, Germany
    The big fight of a small bacterium with osmotic challenges - cellular stress responses to a ubiquitous cue

    Peter Crompton, Laboratory of Immunogenetics, National Institute of Allergy & Infectious Diseases
    Unraveling the Mechanisms of Naturally-Acquired Immunity to Malaria

    Felipe Diaz-Griffero, Department of Microbiology & Immunology, Albert Einstein College of Medicine
    Innate immunity against HIV-1

    David Farrar, Department of Immunology, University of Texas Southwestern Medical Center
    Interfering with allergic diseases

    Douglas B. Weibel, Department of Biochemistry, University of Wisconsin
    Studying bacterial cell division and chromosome segregation using small molecules

    Carol Duffy, Department of Biological Sciences, University of Alabama
    Don't kill the messenger! Does the HSV-1 VP22 protein promote translation by preventing mRNA cleavage by a viral nuclease?

    Blaise Boles, Department of Molecular, Cellular, and Developmental Biology, University of Michigan
    Bacterial Functional Amyloids

    Jyoti Misra Sen, Immune Cells and Inflammation Section, National Institute on Aging
    T cell factor-1 regulated T cell development and function

    Kartik Chandran, Department of Microbiology & Immunology, Albert Einstein College of Medicine
    The lysosomal transporter Niemann-Pick C1 is a critical intracellular receptor for Ebola virus

    Donna Farber, Department of Surgery, Columbia University Medical Center
    Tissue compartmentalization of T cell responses in mice and man

    Spring 2013

    Keith Jarosinski, Department of Microbiology, University of Iowa
    Herpesvirus-induced oncogenesis and transmission

    Shelley M. Payne, University of Texas at Austin
    Shigella pathogenesis: Life in the intracellular environment

    Michael Schmidt, Medical University of South Carolina
    Bacteria, Burden and Bundles: How Copper Surfaces Enhance Patient Safety

    John Butler, Department of Microbiology, University of Iowa
    B cell and repertoire development in swine: a challenge of current paradigms

    Daniel C. DiMaio, Yale University
    Traptamers: artificial transmembrane proteins that inhibit HIV

    John-Demian Sauer, University of Wisconsin-Madison
    The role of inflammasome activation in the induction of cell mediated immunity

    Morgan Huse, Sloan-Kettering Institute
    Lipid-based patterning of the cytoskeleton at the immunological synapse

    Arturo Casadevall, Albert Einstein College of Medicine at Yeshiva University
    Thoughts on the origin of microbial virulence

    Kumaran S. Ramamurthi, National Cancer Institute
    Morphogenesis of large structures during development

    Stokes Peebles, Vanderbilt University
    IL-13 modulation of Th17 cytokine responses

    Michael S. Diamond, Washington University in St. Louis
    New insights into innate and adaptive immune responses against flaviviruses and alphaviruses

    Fall 2012

    Timothy L. Yahr, Department of Microbiology, University of Iowa
    The Pseuomonas aeruginosa type III secretion system: to be on or not to be on, that is the question

    Mark R. Denison, Vanderbilt University
    Coronavirus RNA proofreading: a novel determinant of evolution, replication, and pathogenesis

    Craig D. Ellermeier, Department of Microbiology, University of Iowa
    Activation of ECF sigma factors in response to cell envelope stress in Bacillus subtilis and Clostridium difficile

    Valley Stewart, University of California, Davis
    Transmitter phosphatase control of two-component signal transduction

    Jeffrey Rathmell, Duke University
    Lymphocyte metabolism in immunity and leukemia

    Stacey L. Schultz-Cherry, St Jude Children's Research Hospital
    Pathogenesis of RNA viruses: Fat mice and a viral enterotoxin

    William Shafer, Emory University
    Mechanisms of antibiotic resistance expressed by Neisseria gonorrhoeae: Implications for pathogenesis

    Dennis E. Ohman, Virginia Commonwealth University
    All Stressed Out: Adaptation of a Stress Response System in Pseudomonas for Pathogenesis in Cystic Fibrosis

    Victor J. Torres, New York University Langone Medical Center
    Staphylococcus aureus bi-component toxins: pore-forming toxins involved in the disarmament of the host surveillance system

    Thomas G. Bernhardt, Harvard Medical School
    The ABCs of bacterial cell division

    Carolyn Hovde Bohach, University of Idaho
    Cattle: The silent reservoir of E. coli O157:H7

    Allan Zajac, University of Alabama Birmingham
    Tuning CD8 T cell responses

    Tammy L. Kielian, University of Nebraska Medical Center
    S. aureus biofilms: identifying mechanisms of immune evasion and strategies for therapeutic intervention

    Patrick M. Schlievert, PhD, Department of Microbiology, University of Iowa
    Glycerol Monolaurate-Coenzyme Q Based Formations as Topical Microbicides

    Spring 2012

    Stephen Waggoner, University of Massachusetts Medical School
    Natural killer cells act as rheostats modulating anti-viral T cells

    Balaji Manicassamy, Mount Sinai School of Medicine
    Fighting flu: Immunological insights from novel fluorescent reporter viruses and pandemic strains

    Andrea S. Bertke, University of California, San Francisco
    Differential regulation of HIV-1 and HSV-2 infection in neurons

    Hillel Haim, Dana-Farber Cancer Institute
    Molecular basis of HIV-1 sensitivity to antibodies

    David G. Meckes, University of North Carolina at Chapel Hill
    The far-reaching effects of the Epstein-Barr virus oncoprotein LMP1

    Maria Kalamvoki, University of Chicago
    Immediate early events that co-opt with the HSV-1 genome activation: Cycling around the CLOCK

    Thomas J. Silhavey, Princeton University
    Outer membrane biogenesis in Gram negative bacteria

    Gesila Storz, National Institutes of Health
    The genes that were missed: an expanding university of small RNAs and small proteins

    Marc Johnson, University of Missouri
    Surprising twists and unexpected choices on the path to viral assembly sites

    Michael T. Laub, Massachusetts Institute of Technology
    Specificity and evolution of bacterial signaling pathways

    Michael Dustin, New York University School of Medicine
    The immunological synapse in autoimmunity and viral infection

    Thomas C. Zahrt, Medical College of Wisconsin
    Stress adaptations and Mycobacterium tuberculosis persistence

    Richard J. Roller, Department of Microbiology, University of Iowa
    As if I didn't have enough to do: Multifunctional proteins in HSV egress and cell-cell spread

    Fang Li, University of Minnesota
    Receptor recognition mechanisms of coronaviruses

    Michael Good, Griffith University, Queensland, Australia
    The long road to a malaria vaccine

    Gene Olinger, Jr., US Army Medical Research Institute of Infectious Diseases
    Venezualen equine encephalitis virus replicon (VRP) vaccine development for Ebola & Marburg Viruses

    Katherine R. Spindler, University of Michigan Medical School
    Contributions of viral and host factors to mouse adenoviral encephalitis

    Avinash Bhandoola, University of Pennsylvania
    Establishing T cell identity

    Fall 2011

    David Woodland, Trudeau Institute, Saranac Lake, NY
    Regulation of T cell immunity to respiratory virus infections

    Hai-Hui Xue, Department of Microbiology, University of Iowa
    Lifetime companion of T cells: Wnt paves the path

    Karl Münger, Harvard Medical School
    Perturbation of host cellular regulatory networks by human papillomaviruses

    Wendy Maury, Department of Microbiology, University of Iowa
    Discovery of Ebolavirus receptors

    Yuntao Wu, George Mason University
    Role of chemokine receptor signaling in HIV-1 infection and pathogenesis

    Sanjay Ram, University of Massachusetts
    Complement evasion strategies of Neisseriae: applications in animal models, vaccines and therapeutics

    Anne Simon, University of Maryland
    New paradigms for translation based on studying 3' translational enhancers in plus-strand RNA viruses

    Eric Stewart, Northeastern University
    A molecular basis of bacterial unculturability

    Lindsey Shaw, University of South Florida
    Exploring the pathogenic and drug resistance mechanisms of Staphylococcus aureus

    Michael Apicella, Department of Microbiology, and Patricia Winokur, Department of Internal Medicine, University of Iowa
    Natural selection in 6 days. H. influenzae colonization of the human nasopharynx

    Photini Sinnis, Johns Hopkins Bloomberg School of Public Health
    The malaria sporozoite's journey: From mosquito midgut to mammalian liver

    James Slauch, University of Illinois
    Knowing where you are: regulation of the Salmonella SPI1 type III secretion system

    W. Nicholas Haining, Harvard Medical School
    Molecular mechanisms of T cell exhaustion in humans

    Bradley Jones, Department of Microbiology, University of Iowa
    Exploring the genetic basis of Francisella tularensis virulence

    Spring 2011  

    Craig Ellermeier, Department of Microbiology, University of Iowa
    The role of ECF sigma factors in the cell envelope stress response of Bacillus subtilis and Clostridium difficile

    Mary Wilson, Department of Internal Medicine, University of Iowa
    The intracellular life of Leishmania protozoa

    Susan Carpenter, Iowa State University
    Equine infectious anemia virus envelope evolution

    John Butler, Department of Microbiology, University of Iowa
    The emergence of an immunological model

    Brent Ryckman, University of Montana
    The glycoprotein O of human cytomegalovirus: everybody knows this is nowhere

    Fitnat Yildiz, University of California-Santa Cruz
    Vibrio cholerae biofilms: structural components and regulatory networks

    Paul Thomas, St. Jude Children's Research Hospital
    Not set in stone: peripheral T cell receptor regulation and revision

    John Rossi, City of Hope
    Small RNAs and their therapeutic application for the treatment of HIV infections

    E. John Wherry, University of Pennsylvania
    Regulation of memory T cell differentiation during chronic infections

    Paul Babitzke, Penn State University
    CsrA-mediated global control of gene expression

    Yuying Liang, Emory University
    Lassa fever virus: disease, virulence factors, and immune suppression

    Lee Riley, University of California, Berkeley
    Mycobacterium tuberculosis cell wall lipid regulation as a mechanism for persistence

    William Usinger, Trellis Bioscience, LLC
    Discovery of rare human-derived therapeutic antibodies to treat influenza

    Harald zur Hausen, German Cancer Research Centre, Heidelberg, Germany
    Perspectives of tumorvirus research

    Bradford Gibson, Buck Institute for Research on Aging, Novato, California
    Clinical proteomics for biomarker discovery

    Robert Davey, University of Texas Medical Branch
    Macropinocytosis and induction of cellular signaling events that lead to infection by Ebola virus

    Fall 2010

    Jon Houtman, Department of Microbiology, University of Iowa
    Signal transduction in human T cells

    Caroline Harwood, University of Washington
    Pseudomonas aeruginosa and biofilms: forging new connections

    Howard Berg, Harvard University
    Marvels of bacterial behavior

    Gregory Plano, University of Miami
    Calcium- and cell contact-regulated secretion of virulence proteins by Yersinia pestis, the causative agent of plague

    Ann Hill, Oregon Health & Science University
    T cells and cytomegalovirus: a dangerous obsession?

    Patrick Moore, University of Pittsburgh
    Why do viruses cause cancer?

    Jonathan Karn, Case Western Reserve University
    The ins and outs of HIV latency

    David Francis, South Dakota Center for Infectious Disease Research & Vaccinology
    The role of enterotoxins in colonization of the intestines by enteric pathogens

    Bridget Wilson, University of New Mexico
    High resolution technologies capture FcεRI organization and receptor dynamics

    Paul Lieberman, Wistar Institute
    Mechanisms of genome maintenance: lessons from gammaherpesvirus latency

    Robert Garofalo, University of Texas Medical Branch
    Aspects of innate immunity to human paramyxovirus infections

    David Blehert, USGS - National Wildlife Health Center
    Wildlife disease investigation: bat white-nose syndrome

    Elizabeth Grice, National Institutes of Health
    The skin microbiome in health and disease

    Jeffrey Frelinger, University of Arizona
    Francisella and the immune system - bugs do the darndest things

    Serge Muyldermans, Free University of Brussels, Belgium
    Nanobodies; next generation antibody products for research, diagnostics and therapy

    Ralph Baric, University of North Carolina
    Cruising with noroviruses