Simran Banga, Ph.D.

Postdoctoral Fellow
simran-banga@uiowa.edu 

Lab: 319-335-9919
Fax: 319-335-9006 

Training

Ph.D. Purdue University, Indiana

Research

I am interested in understanding how specific immune response can be enhanced in malaria infection.

Selected Publications Pubmed

1. Banga S, Tan Y, Luo, ZQ. Host nucleus targeting of L. pneumophila effectors by distinct mechanisms. Under Review 
2. Zhu W, Banga S, Tan Y, Zheng C, Stephenson R, Gately J, Luo ZQ. Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. PLoS One. 2011 Mar 9;6(3):e17638. PubMed Central PMCID: PMC3052360. 
3.  Fontana MF, Banga S, Barry KC, Shen X, Tan Y, Luo ZQ, Vance RE. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. PLoS Pathog. 2011 Feb;7(2):e1001289. Epub 2011 Feb 17. PubMed Central PMCID: PMC3040669.
4. Chen C*, Banga S*, Mertens K*, Weber MM, Gorbaslieva I, Tan Y, Luo ZQ, Samuel JE. Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21755-60. Epub 2010 Nov 23. PubMed Central PMCID: PMC3003115.
5. Xu L, Shen X, Bryan A, Banga S, Swanson MS, Luo ZQ. Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector. PLoS Pathog. 2010 Mar 19;6(3):e1000822. PubMed Central PMCID: PMC2841630.
6. Shen X*, Banga S*, Liu Y, Xu L, Gao P, Shamovsky I, Nudler E, Luo ZQ. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cell Microbiol. 2009 Jun;11(6):911-26. Epub 2009 Feb 27. PubMed Central PMCID: PMC2967282.
7. Liu Y, Gao P, Banga S, Luo ZQ. An in vivo gene deletion system for determining temporal requirement of bacterial virulence factors. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9385-90. Epub 2008 Jul 1.  PubMed Central PMCID: PMC2453721.
8. Banga S, Gao P, Shen X, Fiscus V, Zong WX, Chen L, Luo ZQ. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5121-6. Epub 2007 Mar 14.  PubMed Central PMCID: PMC1829273.
   
   *These Authors Contributed Equally