Biosciences Graduate Program

Lubomir P. Turek, MD

Portrait

Staff Physician, Veterans Affairs Medical Center
Professor of Pathology

Contact Information

Primary Office: 10W11 Veterans Affairs Medical Center
Iowa City, IA 52242
Primary Office Phone: 319-338-0581

Email: lubomir-turek@uiowa.edu
Web: Dr. Turek's Research Laboratory

Education

MD, Charles University School of Medicine, Prague, Czech Republic

Student Research Assistant, Biology & Genetics, Czechoslovak Academy of Sciences, Institute Experimental Biology & Genetics, Prague, Czechoslovakia
Research Associate, Virology, Robert Koch Institute, West Berlin, Germany
Cancer Research Fellow of the Damon Runyon-Walter Winchell Fund, Tumor Virology, Department of Microbiology, University of Southern California, Los Angeles
Visiting Associate, Viral Carcinogenesis, National Cancer Institute, Bethesda, MD
Residency, Pathology, National Cancer Institute, Bethesda, MD

Licensure and Certifications

Educational Commission for Foreign Medical Graduates (ECFMG)

Education/Training Program Affiliations

Biosciences Graduate Program
Department of Pathology Graduate Program
Interdisciplinary Graduate Program in Molecular and Cellular Biology

Research Summary

Human papillomavirus transcriptional regulators in cell transformation and cancer.

Center, Program and Institute Affiliations

Holden Comprehensive Cancer Center

Selected Publications

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Lace M, Anson J, Haugen T, Dierdorf J, Turek L.  Interferon treatment of human keratinocytes harboring extrachromosomal, persistent HPV-16 plasmid genomes induces de novo viral integration.  Carcinogenesis.  2014 November 21. 
[PubMed]

Lace M, Ushikai M, Yamakawa Y, Anson J, Ishiji T, Turek L, Haugen T.  The truncated C-terminal E2 (E2-TR) protein of bovine papillomavirus (BPV) type-1 is a transactivator that modulates transcription in vivo and in vitro in a manner distinct from the E2-TA and E8^E2 gene products.  Virology.  2012 August. 429(2):99-111.
[PubMed]

Smith E, Rubenstein L, Haugen T, Pawlita M, Turek L.  Complex etiology underlies risk and survival in head and neck cancer human papillomavirus, tobacco, and alcohol: a case for multifactor disease.  Journal of oncology.  2012. 2012:571862.
[PubMed]

Lace M, Anson J, Klussmann J, Wang D, Smith E, Haugen T, Turek L.  Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric virus-cell mRNAs similar to those found in cervical cancers.  Journal of virology.  2011 February. 85(4):1645-54.
[PubMed]

Rubenstein L, Smith E, Pawlita M, Haugen T, Hamšíková E, Turek L.  Human papillomavirus serologic follow-up response and relationship to survival in head and neck cancer: a case-comparison study.  Infectious agents and cancer.  2011. 6:9.
[PubMed]

Smith E, Rubenstein L, Haugen T, Hamsikova E, Turek L.  Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers.  Cancer causes & control : CCC.  2010 September. 21(9):1369-78.
[PubMed]

Smith E, Pawlita M, Rubenstein L, Haugen T, Hamsikova E, Turek L.  Risk factors and survival by HPV-16 E6 and E7 antibody status in human papillomavirus positive head and neck cancer.  International journal of cancer. Journal international du cancer.  2010 July. 127(1):111-7.
[PubMed]

Lace M, Anson J, Haugen T, Turek L.  Interferon regulatory factor (IRF)-2 activates the HPV-16 E6-E7 promoter in keratinocytes.  Virology.  2010 April. 399(2):270-9.
[PubMed]

Smith E, Parker M, Rubenstein L, Haugen T, Hamsikova E, Turek L.  Evidence for vertical transmission of HPV from mothers to infants.  Infectious diseases in obstetrics and gynecology.  2010. 2010:326369.
[PubMed]

Smith E, Rubenstein L, Hoffman H, Haugen T, Turek L.  Human papillomavirus, p16 and p53 expression associated with survival of head and neck cancer.  Infectious agents and cancer.  2010. 5:4.
[PubMed]

Date Last Modified: 06/07/2014 - 21:56:23