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Professor of Chemical & Biochemical Engineering
Office: 4132 SCIowa City, IA 52242
Email: email@example.comWeb: More About Dr. Murhammer - Related Websites and Resources
BS, Chemistry, Oregon State UniversityMS, Chemical Engineering, Oregon State UniversityPhD, Chemical Engineering, University of Houston
Biosciences Graduate ProgramInterdisciplinary Graduate Program in Human Toxicology
Viral Insecticide Production
We are developing methods to produce viral insecticides in continuous systems that overcome accumulation of the few polyhedra (FP) mutants and defective interfering particles (DIP) characteristic of current continuous systems. DIP and FP mutant accumulation are being overcome by applying novel bioreactor designs and using molecular biology techniques, respectively. This research is being conducted in collaboration with investigators in the Department of Microbiology (College of Medicine) and the Department of Entomology at Iowa State University.
We are investigating the oxidative stress resulting from the baculovirus infection of insect cells and the unique role of a baculovirus encoded Copper-Zinc Superoxide Dismutase homolog in this process. In a related project, the effect of carbon dioxide accumulation (which commonly occurs in large-scale bioreactors) on oxidative stress is also being investigated. This research has involved collaboration with groups in the Department of Free Radical & Radiation Biology (College of Medicine) and the Department of Molecular Biology at the University of Wyoming.
Date Last Modified: 08/04/2015 -
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