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Associate Professor of Internal Medicine
- Infectious Diseases
Primary Office: C327 GHIowa City, IA 52242
Email: firstname.lastname@example.orgWeb: HIV ProgramWeb: MATEC
MD, University of Iowa
Residency, Internal Medicine, University of Wisconsin Hospital & Clinics, Madison, WisconsinFellowship, Infectious Diseases, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Clinical Investigation, Bethesda, Maryland
Medical License, Iowa Board of MedicineInfectious Diseases, American Board of Internal Medicine Internal Medicine, American Board of Internal Medicine
Interdisciplinary Graduate Program in Molecular and Cellular Biology
Dr. Meier's research interests are in human immunodeficiency virus and cytomegalovirus infections. He directs the University of Iowa HIV Clinical Trials Program. His laboratory studies human cytomegalovirus, with particular attention to the molecular mechanisms underlying viral replication, persistence, and reactivation and to the functioning of these mechanisms in different types of human cells and tissues. Cytomegalovirus is the most common infectious cause of birth defects and reactivates to cause life-threatening disease in persons with impaired immunity, such as persons having AIDS or receiving a stem cell or solid organ transplantation.
Projects that are currently active in the laboratory include: 1) Characterization of the molecular pathways involved in silencing the human cytomegalovirus major immediate-early enhancer/promoter, the master control switch for viral replication. 2) Determination of the stimuli and signaling pathways involved in human cytomegalovirus reactivation in quiescently infected cells. 3) Characterization of human cytomegalovirus infection in neutrophils, macrophages, dendritic cells, and vascular tissues. 4) Evaluation of the role of human adipose tissue in cytomegalovirus dissemination and disease.
Date Last Modified: 10/09/2015 -
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