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Associate Professor of Internal Medicine
- Hematology, Oncology and Blood and Marrow Transplantation
Lab: 5204 MERFIowa City, IA 52242
BS, Chemical Engineering, The University of Virginia, Charlottesville, VAPhD, Neurobiology, Duke University, Durham, NC
Post Doctoral, Duke University Medical Center
Biosciences Graduate ProgramInterdisciplinary Graduate Program in Molecular and Cellular BiologyInterdisciplinary Graduate Program in Neuroscience
My lab develops RNA-based technologies to understand and treat disorders of the nervous system. We are using RNA aptamers (structural, artificial RNAs) that bind cell surface proteins expressed in the nervous system to directly activate signaling pathways, and to deliver siRNAs to specific cell types. We will apply these tools to elucidate mechanisms of disease in animal models and to develop novel therapeutic approaches. As part of this work, we are also developing novel RNA aptamer identification methodologies, including cell-based and whole animal-based aptamer screening approaches.
Date Last Modified: 07/22/2014 -
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