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Professor of Internal Medicine
- Pulmonary, Critical Care and Occupational MedicineProfessor of
Occupational and Environmental Health, College of Public Health
Office: W219B GHIowa City, IA 52242
Office Phone: 319-353-8551
Email: email@example.comWeb: Internal Medicine
AB, Brown University, Providence, Rhode IslandMD, Brown University, Providence, Rhode IslandMSc, Occupational and Environmental Health, University of Iowa Hospitals and Clinics, College of Public Health
Residency, Internal Medicine, UCSF - Fresno Medical Education Program, Fresno, CAChief Resident, Internal Medicine, UCSF - Fresno Medical Education Program, Fresno, CAFellowship, Pulmonary and Critical Care Medicine, University of Iowa Carver College of Medicine
ABIM, Special Certification in Critical CareABIM, Subspecialty Board in Pulmonary DiseasesAmerican Board of Internal Medicine
Biosciences Graduate ProgramInterdisciplinary Graduate Program in Human ToxicologyInterdisciplinary Graduate Program in Translational Biomedicine
Study of the modulation of airway inflammatory responses in asthma.
1) Role of CpG oligodeoxynucleotides in the modulation of the airway inflammatory response in a murine model of asthma. We have previously demonstrated that administration of CpG at the time of sensitization to allergen (ovalbumin) in a murine model of asthma can prevent the development of eosinophilic inflammation and bronchial hyperreactivity. We are now in the process of studying (in vitro and in vivo) the mechanisms through which CpG ODN can accomplish these results and also examining how administration of CpG ODN (with and without specific immunotherapy) can lead to treatment of established inflammatory responses.
2) Dendritic cells in antigen-mediated asthma. We are developing murine and human (in vitro) models to evaluate the role of dendritic cells in sensitization and re-challenge with antigen in asthma.
Date Last Modified: 06/07/2014 -
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