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Associate Professor of BiologyAssociate Professor of
- Nephrology, Dialysis and Transplantation
Office: 459A BBIowa City, IA 52242
Office Phone: 319-335-0180
Email: firstname.lastname@example.orgWeb: More About Dr. Manak - Related Websites and Resources
BS, Biology, Trinity CollegeMS, Molecular Biology/Biochemistry; Cell/Developmental, New York UniversityPhD, Molecular Biology, Columbia University
Post Doctoral, Developmental Genetics, Stanford UniversityPost Doctoral, Molecular Genetics, Stanford University
Biosciences Graduate ProgramInterdisciplinary Graduate Program in GeneticsInterdisciplinary Graduate Program in InformaticsInterdisciplinary Graduate Program in Molecular and Cellular Biology
Research in my laboratory covers four different but not mutually exclusive areas: 1) fruit fly models to understand human diseases such as epilepsy and cancer, 2) high-throughput genomics technologies to identify the genetic basis of human disease, 3) genomic technology development to facilitate identification of important mutations and novel transcript isoforms in both humans and model organisms, and, 4) whole-genome transcriptome and chromatin analysis in established and emerging model organisms. Over the last few years, I have focused a significant portion of my efforts on the genetics/genomics of human disease. These efforts have resulted in discovery of new spina bifida and cleft lip and palate candidate genes, as well as a recombination hotspot associated with BOR (Branchio-Oto-Renal syndrome). We have also discovered that the same gene (prickle) mutated in flies, mice and humans causes epilepsy and we are elucidating the mechanism of epilepsy in our fly model.
Date Last Modified: 06/07/2014 -
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