Biosciences Graduate Program

Raymond J. Hohl, MD, PhD

Portrait

Emeritus Professor of Internal Medicine  - Hematology, Oncology and Blood and Marrow Transplantation

Contact Information

Primary Office: SE313 GH
Iowa City, IA 52242
Primary Office Phone: 319-356-8110

Lab: 5219 MERF
Iowa City, IA 52242
Phone: 319-335-8272

Email: raymond-hohl@uiowa.edu

Education

BS, Biochemistry, University of Illinois
MD, Rush Medical College, Rush University
PhD, Pharmacology, Graduate College, Rush University

Residency, University of Chicago
Fellowship, Hematology/Oncology, University of Chicago

Licensure and Certifications

American Board of Clinical Pharmacology
ABIM. Subspeciality Board in Medical Oncology
American Board of Internal Medicine
National Board of Medical Examiners

Education/Training Program Affiliations

Biosciences Graduate Program
Interdisciplinary Graduate Program in Molecular and Cellular Biology
Interdisciplinary Graduate Program in Translational Biomedicine
Medical Scientist Training Program

Research Summary

Dr. Hohl's research interests focus on understanding the interactions between mevalonic acid and cholesterol biosynthesis and the proliferation of acute myeloid leukemia cells. These studies investigate the relative affinities of various growth regulating proteins, such as RAS and KREV1, for the isoprene intermediates of the mevalonic acid to cholesterol biosynthetic pathway. His clinical interests involve evaluation of the potential role for pharmacologic inhibitors of this biosynthetic pathway in the treatment of various hematologic malignancies and solid tumors. Additionally, he has continued interest in studying how various erythrocyte enzymothathies predispose the human red blood cell to drug-induced oxidative damage.

Date Last Modified: 07/31/2014 - 12:51:37