Biosciences Graduate Program

Andrew Norris, MD, PhD

Portrait

Associate Professor of Pediatrics  - Endocrinology and Diabetes
Associate Professor of Biochemistry

Contact Information

Primary Office: 1270B CBRB
Iowa City, IA 52242
Primary Office Phone: 319-335-7383

Email: andrew-norris@uiowa.edu
Web: Norris Laboratory

Education

BS, Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts
MD, Medicine, Washington University School of Medicine, St. Louis, Missouri
PhD, Molecular Biology, Washington University School of Medicine, St. Louis, Missouri

Residency, University of Iowa Hospitals & Clinics, Iowa City, Iowa
Fellowship, Children's Hospital Boston & Joslin Diabetes Center, Boston, Massachusetts
Post Doctoral, Joslin Diabetes Center

Licensure and Certifications

Pediatric Endocrinology

Education/Training Program Affiliations

Biosciences Graduate Program
Department of Biochemistry PhD
Interdisciplinary Graduate Program in Informatics

Research Summary

Our work is currently focused on three questions. (1) How does fetal over- or under-exposure to macronutrients incite poor metabolism? To study this, we have developed an in vivo fetal model accomplished via unilateral infusion of macronutrients into the uterine artery. (2) How does cystic fibrosis cause diabetes? We are working collaboratively with other University of Iowa investigators to better understand the pathophysiology of cystic fibrosis related diabetes. (3) How does direct action on skeletal muscle of the thiazolidinediones and their target, the transcription factor PPARgamma, help treat diabetes? We have recently demonstrated that PPARgamma directly augments the PDK1:AKT nexus of insulin signaling despite increasing muscle lipid uptake.

Center, Program and Institute Affiliations

Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases
Fraternal Order of Eagles Diabetes Research Center
Obesity Initiative

Date Last Modified: 06/07/2014 - 21:56:23