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Mentor: Shahram Khademi, PhD
Year Entered Into Program: 2007-2012
PhD Institution: Department of Biochemistry, Univ of Iowa
My research in Dr. Khademi’s laboratory focuses on the structure and function of biologically important prokaryotic membrane proteins. About 30% of the genes in a cell encode membrane proteins. However, less than 0.5% of entries in PDB (a database for the coordinates of proteins with known structures) are membrane proteins. While more than 60% of drug receptors are membrane proteins, our knowledge of their structures and functions are very limited. My research goal is to determine the x-ray structure of essential membrane proteins from H. pylori. I will also conduct functional assays to determine the mechanism of action of these membrane proteins.
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