Ophthalmology And Visual Sciences

Michael Wall, MD


Specialty: Neuro-Opthalmology
Director, Neuro-Ophthalmology Clinic, Neurology
Professor of Neurology
Professor of Ophthalmology and Visual Sciences

Contact Information

Primary Office: 2149 RCP
Iowa City, IA 52242

Email: michael-wall@uiowa.edu


MD, Medicine, Tulane University

Residency, Neurology, Washington University in St. Louis
Fellowship, Neuro-ophthalmology, Harvard University

Research Summary

Dr. Wall's research has two arms. The first is to develop strategies of visual field testing that detect visual field defects at an earlier stage and visual field change at an earlier time. To achieve these goals, we have been studying mechanisms of perimetric variability. We have been funded for this with a VA Merit review for the past 12 years. During this time we have shown that a substantial portion of the variability of perimetry is due to the stimulus size chosen. In the process, we have developed a method of visual field testing, motion perimetry, that takes advantage of these findings to lower retest variability. We are in the fourth year of a 5 year study that follows glaucoma patients with four visual field tests to determine if larger stimuli result in earlier detection of visual field change. The second arm of the research is to study idiopathic intracranial hypertension (pseudotumor cerebri) a disease of overweight women in the childbearing years that causes headache and blindness. Our goal is to find the cause of the disease and to develop evidence-based treatment strategies. Currently all treatment decisions are based on data that is retrospective and uncontrolled. Our clinical trial has now been funded by the NIH for $16 million over 5 years. The specific aims of 1) determining if diet and acetazolamide is superior to diet alone; 2) with the help of Edwin Stone's laboratory, using a genome wide association study better understand the mechanism of idiopathic intracranial hypertension.

Selected Publications

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Vislisel J, Doyle C, Johnson C, Wall M.  Variability of rarebit and standard perimetry sizes I and III in normals.  Optom Vis Sci.  2011 May. 88(5):635-9.

Johnson C, Wall M, Thompson H.  A history of perimetry and visual field testing.  Optom Vis Sci.  2011 January. 88(1):E8-15.

Sample P, Dannheim F, Artes P, Dietzsch J, Henson D, Johnson C, Ng M, Schiefer U, Wall M.  Imaging and Perimetry Society standards and guidelines.  Optom Vis Sci.  2011 January. 88(1):4-7.

Dave S, Longmuir R, Shah V, Wall M, Lee A.  Intracranial hypertension in systemic lupus erythematosus.  Semin Ophthalmol.  2008. 23(2):127-33.

Wendel L, Lee A, Boldt H, Kardon R, Wall M.  Subretinal neovascular membrane in idiopathic intracranial hypertension.  Am J Ophthalmol.  2006 March. 141(3):573-4.

Anderson A, Johnson C, Fingeret M, Keltner J, Spry P, Wall M, Werner J.  Characteristics of the normative database for the Humphrey matrix perimeter.  Invest Ophthalmol Vis Sci.  2005 April. 46(4):1540-8.

Lee A, Eggenberger E, Galetta S, Kerrison J, Miller N, Kirby P, Wall M, Hitchon P, Kardon R.  Neuro-ophthalmic manifestations of hemangiopericytoma.  Semin Ophthalmol.  2004. 19(3-4):95-100.

Date Last Modified: 08/04/2015 - 09:28:35