Ophthalmology And Visual Sciences

Val Sheffield, MD, PhD

Portrait

Martin & Ruth Carver Chair in Genetics
Investigator, Howard Hughes Medical Institute
Director, Division of Medical Genetics
Director, Interdepartmental Research Program in Human Molecular Genetics
Professor of Pediatrics  - Medical Genetics
Professor of Ophthalmology and Visual Sciences

Contact Information

Lab: 4181 MERF
Iowa City, IA 52242
Phone: 319-335-6898

Email: val-sheffield@uiowa.edu

Education

BS, Zoology, Brigham Young University, Provo, Utah
MS, Developmental Biology, Brigham Young University, Provo, Utah
PhD, Developmental Biology, University of Chicago, Chicago, Illinois
MD, Medicine, with Honors, University of Chicago, Chicago, Illinois

Residency, Pediatrics, University of California, San Francisco, California
Fellowship, Medical Genetics, University of California, San Francisco, California

Licensure and Certifications

Permanent Iowa license to practice medicine and surgery
Board certified in Clinical Molecular Genetics
Board certified in Clinical Medical Genetics
Diplomate of the National Board of Medical Examiners

Education/Training Program Affiliations

Biosciences Graduate Program
Interdisciplinary Graduate Program in Genetics
Interdisciplinary Graduate Program in Informatics
Interdisciplinary Graduate Program in Neuroscience
Interdisciplinary Graduate Program in Translational Biomedicine
Medical Scientist Training Program

Research Summary

My laboratory is interested in identifying and understanding the function of genes which cause a variety of human disorders. Our research efforts have focused on the molecular genetics of monogenic disorders, as well as polygenic and multifactorial disorders. Our research efforts have resulted in the mapping of many different disease loci. In addition, we have used positional cloning methods to identify genes involved in a number of different diseases including hereditary blindness and deafness. Efforts are currently underway to use positional cloning strategies to identify additional disease-causing genes. Complex genetic disorders currently under investigation in the laboratory include hypertension, obesity, congenital heart disease and autism. In addition, we have worked on developing and improving techniques for disease mapping, positional cloning, and mutation detection. We have also had an active role in the human genome project and the rat genome project.

Date Last Modified: 07/31/2013 - 10:51:40