Ophthalmology And Visual Sciences

Michael G. Anderson, PhD

Portrait

Associate Professor of Molecular Physiology and Biophysics
Associate Professor of Ophthalmology and Visual Sciences

Contact Information

Office: 6-430 Bowen Science Building
Iowa City, IA 52242
Office Phone: 319-335-7839

Lab: 6-429 Bowen Science Building
Iowa City, IA 52242
Phone: 319-335-7838

Email: michael-g-anderson@uiowa.edu
Web: More information

Education

BA, Biology, Luther College, Decorah, IA
PhD, Physiology and Biophysics, University of Iowa, Iowa City, IA

Post Doctoral, Postdoctoral Fellow with Dr. Simon John, The Jackson Laboratory, Bar Harbor, ME

Education/Training Program Affiliations

Biosciences Graduate Program
Department of Molecular Physiology and Biophysics PhD
Interdisciplinary Graduate Program in Genetics
Interdisciplinary Graduate Program in Neuroscience
Interdisciplinary Graduate Program in Translational Biomedicine
Medical Scientist Training Program

Research Summary

Research in my laboratory is aimed at understanding fundamental physiological properties of the eye and the pathophysiological mechanisms underlying a variety of complex eye diseases. Of primary interest are the glaucomas, a leading cause of blindness that affects approximately 70 million people worldwide. Glaucoma typically involves three types of events: molecular insults compromising the anterior chamber, increased intraocular pressure, and neurodegenerative retinal ganglion cell loss. Not surprisingly, the biological relationships linking these events are complex. Our approach for studying these events is founded in functional mouse genetics and supplemented by a variety of molecular, cellular, immunological, and neurobiological techniques. The premise for this approach is that stringently performed genetic studies offer great potential for overcoming the natural biological complexity of glaucoma. Current projects in the lab emphasize glaucoma phenotypes occuring in the front of the eye, including the molecular genetics of pigmentary glaucoma, exfoliative glaucoma, and central corneal thickness. We are also interested in new mouse models of glaucoma and have been studying an early onset form of glaucoma in nee mice that is associated with abnormalities of the aqueous drainage structures. In the long term, these studies will contribute to an increased understanding of eye diseases such as glaucoma, and ultimately to improved human therapies.

Center, Program and Institute Affiliations

Stephen A. Wynn Institute for Vision Research

Date Last Modified: 06/07/2014 - 21:56:23