Pharmacology

Mailing Address

Office: E311 GH
Iowa City, IA 52242
Phone: +1 319 356 2706
Email: donald-heistad@uiowa.edu

Office/Lab Address

Office/Lab: E311 GH
Iowa City IA, 52242
Phone: +1 319 356 2706

Education

Residency, University of Chicago ,
Fellowship, The University of Iowa,
MD, University of Chicago, 1963

Appointments

Primary: Internal Medicine
Secondary: Pharmacology

Center and Program Affiliations

• Biosciences Graduate Program

Research Summary

Dr. Heistad's clinical interests include general cardiology. His research interests focus on gene transfer to blood vessels, mechanisms of intracranial hemorrhage, pathophysiology of aortic valvular stenosis; and vascular biology of atherosclerosis and hypertension. A major focus of these studies is on the role of oxidative stress and antioxidant mechanisms.

Publications

• Early change in ferumoxytol-enhanced magnetic resonance imaging signal suggests unstable human cerebral aneurysm: a pilot study. Stroke 43(12) : 3258-65, 2012. [PubMed]
• Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results. Stroke 43(7) : 1964-7, 2012. [PubMed]
• Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid artery in rabbit via ATP-sensitive K+ channels. Am J Physiol Heart Circ Physiol 289(5) : H2244-50, 2005. [PubMed]