Isaac Samuel, MD


Bariatric, Gastrointestinal, and Minimally-Invasive Surgeon
Program Director, Bariatric Surgery Fellowship Program
Director, UI Obesity Surgery Program
Associate Professor of Surgery  - Gastrointestinal, Minimally-invasive and Bariatric Surgery

Contact Information

Primary Office: 4625 JCP
Iowa City, IA 52242
Primary Office Phone: 319-384-7220



MBBS, Bangalore Medical College, Bangalore University, Karnataka State, India

Internship, Surgery and Medicine, Bangalore Medical College Hospitals, Karnataka State, India
Residency, Surgery and Medicine, St. Martha's and St. Philomena's Hospitals, Karnatake State, India
Residency, Surgery and Medicine, Tiruvella Medical Mission Hospital, Kerala State, India
Residency, Emergency Room, Eastbourne District, General Hospital, Eastbourne, UK
Residency, General Surgery, Leeds General Infirmary, University of Leeds, UK
Registrar, General Surgery, St. Thomas' Hospital, University of London, UK
Fellowship, Research, General Surgery, Northwestern University, Chicago, IL
Residency, General Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL

Licensure and Certifications

Iowa Medical License Iowa Board of Medicine
Certified, Advanced Trauma Life Support
Fellow (FACS) American College of Surgeons
Board Certified, General Surgery American Board of Surgery
FRCS Royal College of Surgeons, Glasgow, UK

Research Summary

Acute pancreatitis pathogenesis: The laboratory investigates the role of acinar cell signaling pathways such as the stress kinase (p38, JNK, ERK) pathway and the Akt/NFkB pathway as applied to a novel hypothesis for gallstone pancreatitis pathogenesis. The role of pancreatic hyperstimulation via G-protein coupled receptors (CCK receptor and cholinergic receptor) and their regulation by a novel group of proteins called RGS (regulation of G-protein signaling) proteins are also being investigated. Our long- term goal is to elucidate the pathogenesis of acute pancreatitis with a view to implement new treatment modalities. Current funding from NIH is a NIDDK K08 Career Development Award. Samuel Clinical Research: Measurement of physical activity and energy expenditure in bariatric surgery patients to improve pre-operative evaluation and long-term post-operative outcomes.

Date Last Modified: 06/07/2014 - 21:56:23