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Andrew H. Woods Chair of PsychiatryDirector, Iowa Neuroimaging ConsortiumProfessor of Psychiatry
Primary Office: ,
Office: T214 General Hospital200 Hawkins DriveIowa City, IA 52242
Email: email@example.comWeb: More information
BA, Philosophy, University of Nebraska, Lincoln, NEBA, History, University of Nebraska, Lincoln, NEBA, English, University of Nebraska, Lincoln, NEMA, English, Radcliffe College, Cambridge, MAPhD, English Literature, University of Nebraska, Lincoln, NEMD, Psychiatry, University of Iowa College of Medicine, Iowa City, IA
Fellowship, English Literature, Oxford University, United KingdomResidency, Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, IA
Medical License, Iowa Board of Medical ExaminersBoard Certification, American Board of Psychiatry and Neurology
Biosciences Graduate ProgramInterdisciplinary Graduate Program in NeuroscienceInterdisciplinary Graduate Program in Translational BiomedicineMedical Scientist Training Program
I have been leading multifaceted research programs to study nosology, cognitive/affective
neuroscience, genet ics, and brain mechanisms of psychoses for many years. I have also done
extensive work in mood disorders. We were among the first investigators to use CT and SPECT to study brain abnormalities in schizophrenia and bipolar disorder. When MR imaging became available during t he mid-l980s, we conduct ed and published t he f irst quant it at ive MR study of brain abnormalities in schizophrenia and also the first in bipolar disorder. We have invested substantial effort in developing many aspects of MR imaging, including software development that yields measures of brain components, with careful attention t o reliability and validity. As our
methods have become increasingly automated, we have been careful to ensure that accuracy is not sacrificed to efficiency. We also have a strong team that uses imaging to explore issues in cognitive and affective neuroscience. We have conduct ed PET studies of many aspects of
cognition and emotion, including attention, memory, language, emot ion, and social
cognition. Our current work relies heavily on fMR, since it permits us t o examine large samples, and thereby to address quest ions about diversity within disease phenot ypes. I have also led a T32 program in Clinical Neurobiology t hat has t rained a large number of trainees in the tools of neuroimaging and cognitive neuroscience; nearly all of t hese have gone on t o have successf ul careers both at Iowa and at other institutions.
I conducted t he first modern empirical study of the relationship between creativity and mental illness; this study was facilitated by my connect ion with the Iowa Writers’ Workshop, the oldest
and best -known creative writing program in the country; it has a rotating faculty, and so I was
able to study visiting writers, such as Kurt Vonnegut , John Cheever, and John Irving. I
found that creative writers have a higher rate of mood disorder t han a noncreative comparison group and that creativity and mood disorders t end to run together in families. I am currently
conducting a second study that examines these quest ions in a broader range of creative
subject s (i.e., both artists and scientists, including many Nobel laureat es), studying their brains with structural and function MR imaging and collect ing blood f or genet ic analyses. Because this topic is of broad general interest, because pointing out a relationship between creativity and mental illness helps to reduce stigma, I have also written a book and articles on the topic for the general public.
Effects of age on white matter integrity and negative symptoms in schizophrenia.
2015 January. 161(1):29-35.
A genome-wide CNV analysis
of schizophrenia reveals a potential role for a multiple-hit model.
Am J Med Genet B.
2014 December. 165B(8):619-626.
Secrets of the Creative Brain.
2014 June 25. Koziol L,
Consensus paper: The cerebellum's role in movement and cognition.
2014 January. 13(1):151-177.
Relapse Duration, Treatment Intensity, and Brain Tissue Loss in Schizophrenia: A Prospective Longitudinal MRI Study.
Am J Psychiatry.
Eyeblink conditioning in unmedicated schizophrenia patients: A positron emission tomography study.
2013 March. 214(3):402-409.
MAPK14 and CNR1 gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse.
Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies.
Neurosci Biobehav Rev.
Spatial characteristics of white matter abnormalities in schizophrenia.
The MCIC Collection: A Shared Repository of Multi-Modal, Multi-Site Brain Image Data from a Clinical Investigation of Schizophrenia.
Date Last Modified: 08/04/2015 -
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