Pharmacology

Pimonrat Ketsawatsomkron, PhD

Portrait

Associate of Pharmacology

Contact Information

Office: 2-372 Bowen Science Building
Iowa City, IA 52242
Office Phone: 319-335-6954

Lab: 2-340 Bowen Science Building
Iowa City, IA 52242
Phone: 319-335-8926

Email: pim-kets@uiowa.edu

Education

B. Pharm, Pharmacy, Pharamcology School, Mahidol University, Thailand
PhD, Biomedical Science, Medical College of Georgia, GA

Research Assistant, Pharmacy School Mahidol University, Thailand
Graduate Research Assistant, Medical College of Georgia, August, GA
Post Doctoral, Department of Internal Medicine, University of Iowa
Post Doctoral, Department of Pharmacology, University of Iowa

All Publications

Prasad A, Nuno D, Koval O, Ketsawatsomkron P, Li W, Li H, Shen F, Sigmund C, Anderson M, Lamping K, Grumbach I.  Differential Control of Calcium Homeostasis and Vascular Reactivity by CaMKII. .  Hypertension.  2013 August. 62(2):434-441.
[Link]

Littlejohn N, Siel Jr. R, Ketsawatsomkron P, Pelham C, Pearson N, Hilzendeger A, Buehrer B, Weidemann B, Li H, Davis D, Thompson A, Liu X, Cassell M, Sigmund C, Grobe J.  Hypertension in Mice with Transgenic Activation of the Brain Renin-Angiotensin System is Vasopressin-Dependent. .  Am J Physiol Regul Integr Comp Physiol..  2013 May. 304(10):R818-R828.
[Link]

Pelham C, Ketsawatsomkron P, Groh S, Grobe J, de Lange W, Ibeawuchi S, Keen H, Weatherford E, Faraci F, Sigmund C.  Cullin-3 Regulates Vascular Smooth Muscle Function and Arterial Blood Pressure via PPARγ and RhoA/Rho-kinase..  Cell Metabolism .  2012 October 3. 16(4):462-472.
[Link]

Ketsawatsomkron P, Lorca R, Keen H, Weatherford E, Liu X, Pelham C, Grobe J, Faraci F, England S, Sigmund C.  PPARγ Regulates Resistance Vessel Tone Through a Mechanism Involving RGS5-mediated Control of PKC and BKCa Channel Activity..  Circ. Res..  2012. 111(11):1446-1458.
[Link]

Santillan M, Pelham C, Ketsawatsomkron P, Santillan D, Yang B, Hunter S, Sigmund C.  Development and Characterization of an Indoleamine 2,3-dioxygenase (IDO) Deficient Mouse Model of Preeclampsia..  30th Annual Scientific Meeting SMFM, Chicago, IL.  2010. 

Ketsawatsomkron P, pelham C, Groh S, Keen H, Faraci F, Sigmund C.  Does Peroxisome Proliferator-Activated Receptor {gamma} (PPARγ) Protect from Hypertension Directly Through Effects in the Vasculature? .  J Biol Chem..  2010. 285:9311-9316.
[Link]

Ketsawatsomkron P, Pelham C, Groh S, Keen H, Faraci F, Sigmund C.  Does PPARγ protect from hypertension directly through effects in the vasculature? .  J Biol Chem.  2010. 285(13):9311-9316.

Ketsawatsomkron P, Stepp D, Fulton D, Marrero M.  Molecular Mechanism of ANG II –induced insulin resistance in aortic vascular smooth muscle cells via the activation of PTP-1B..  Vascul Pharmacol. .  2010. 53(3-4):160-168.
[Link]

Ketsawatsomkron P, Pelham C, Faraci F, Sigmund C.  Role of vascular muscle Peroxisome Proliferator-Activated Receptor γ (PPARγ) in the regulation of resistance vessel tone. .  FASEB J..  2010. 24:776.2.

Ali M, Ketsawatsomkron P, Belin de Chantelemele E, Mintz J, Muta K, Doyle C, Black S, Tremblay M, Fulton D, Marrero M, Stepp D.  Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone. .  Circ Res..  2009 November. 105(10):1013-1022.
[Link]

Ketsawatsomkron P, Pelham C, Faraci F, Sigmund C.  Role of vascular muscle peroxisome proliferator-activated receptor-γ (PPARG) in the regulation of resistance vessel tone. .  Hypertension.  2009. 54(4):e28.

Pelham C, De Lange W, Ketsawatsomkron P, Groh S, Faraci F, Sigmund C.  Roles of basal NO and Rho kinase in vascular dysfunction in transgenic mice expressing vascular muscle-specific dominant negative PPARγ (PPARG)..  Hypertension.  2009. 54(4):e47.

Borges G, Morgan D, Ketsawatsomkron P, Rahmouni K, Sigmund C.  Tachycardia caused by interference with PPARγ (PPARG) in vascular smooth muscle in mice is related to autonomic imbalance and baroreflex dysfunction..  Hypertension.  2009. 54(4):e101.

Ketsawatsomkron P, de Lange W, pelham C, Halabi C, Faraci F, Sigmund C.  Vascular dysfunction in transgenic mice expressing a PPARγ interfering mutation specifically in vascular muscle: role of aortic rho kinase. .  FASEB J..  2009. 23:952.10.

Faraci F, Modrick M, Ketsawatsomkron P, Lynch C, Sigmund C.  Vasodilation to angiotensin (1–7) in vitro and in vivo is markedly impaired following vascular muscle-specific interference with PPARγ function. .  Hypertension.  2009. 54(4):e120.

Elgebaly M, Kelly A, Harris A, Elewa H, Ketsawatsomkron P, Marrero M, Ergul A.  Impaired insulin-mediated vasorelaxation in a non-obese model of type 2 diabetes: Role of endothelin-1. .  Can J Physiol Pharmacol. .  2008. 86(6):358-364.
[PubMed]

Chantemele E, Ketsawatsomkron P, Marrero M, Stepp D.  Protein Tyrosine Phosphatse 1B is a negative regulator of alphaadrenergic vasoconstriction in mouse aorta. .  FASEB J..  2008. 22:744.8.

Ketsawatsomkron P, Chantemele de E, Muta K, Fulton D, Stepp D, Marrero M.  Regulation of vascular insulin signaling by protein tyrosine phosphatse 1b (PTP-1B) in mouse model of obesity. .  FASEB J..  2008. 22:1226.17.

Ketsawatsomkron P, Banes-Berceli A, Rudic R, Stepp D, Fulton D, Marrero M.  Roles of protein tyrosine phosphatase 1b (PTP1B) in vascular function and remodeling in vivo. .  FASEB J.  2007. 21:737.25.

Banes-Berceli A, Ketsawatsomkron P, Marrero M, Lee D, Brands M.  Characterization of the expression and activation of the members of the JAK family in medulla, cortex and glomerular mesangial cells (GMC) in PPARα knock-out (KO) and wild-type (WT) mice. .  FASEB J.  2006. 20(A1286).

Sachidanandam K, ketsawatsomkron P, Elewa H, Banes-Berceli a, Marrero M, Ergul A.  Impaired insulin-mediated signaling and vasorelaxation in a non-obese model of type 2 diabetes: impact of high fat diet. .  ATVB.  2006. 26(5):e86.

Ketsawatsomkron P, Banes-Berceli A, Marrero M.  Molecular mechanisms of Angiotensin II (ANG II)-induced insulin resistance in rat aortic smooth muscle cells (VSMC)..  FASEB J.  2006. 20(A1172).

Brooks C, ketsawatsomkron P, Sui Y, Wang J, Wang C, Yu F, Dong Z.  Acidic pH inhibits ATP depletion-induced tubular cell apoptosis by blocking caspase-9 activation in apoptosome..  Am J Physiol Renal Physiol. .  2005 August. 289(2):F410-F419.
[Link]

Ketsawatsomkron P, Shaw S, Banes-Berceli A, Marrero M.  PPARγ ligands block Angiotensin II-induced insulin resistance in macrovessels. .  Diabetes.  2005. 54(sppl 1):1989-P.

Faraci F, Modrick M, Ketsawatsomkron P, M L, D S. 

Date Last Modified: 09/11/2014 - 10:05:44