Stead Family Department of Pediatrics

Steven F. Stasheff, MD, PhD

Portrait

Assistant Professor of Pediatrics  - Neurology and Developmental and Behavioral Pediatrics
Assistant Professor of Biomedical Engineering

Contact Information

Primary Office: 2510 JCP
Iowa City, IA 52242
Primary Office Phone: 319-335-8250

Email: steven-stasheff@uiowa.edu

Education

BA, Biology and Physics, University of North Carolina, Chapel Hill, North Carolina
PhD, Pharmacology, Duke University, Durham, North Carolina
MD, Medicine, Duke University, Durham, North Carolina

Internship, Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Residency, Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Residency, Pediatric Neurology, Children's Hospital, Boston, Massachusetts
Fellowship, Neuro-Ophthalmology, New England Medical Center, Boston, Massachussetts
Post Doctoral, Retinal Neurophysiology, Massachussetts General Hospital, Boston, Massachussetts

Licensure and Certifications

Iowa Medical License
Certification in Neurology with Special Competency in Child Neurology: American Board of Psychiatry and Neurology, Inc.
Eligible for Certification, American Board of Pediatrics

Education/Training Program Affiliations

Biosciences Graduate Program
Interdisciplinary Graduate Program in Neuroscience

Research Summary

Research interests center on the fundamental physiologic mechanisms of neurologic diseases affecting the visual system, and on the role that central nervous system (CNS) plasticity may play in both the pathogenesis and potential treatments for such disorders. Ongoing investigations aim to better understand electrophysiologic changes that occur in hereditary retinal degeneration, the most common inherited cause of blindness, and also a central feature of many neurodegenerative disorders in children and adults, including those that cause severe mental retardation, motor disability, and seizures.

Center, Program and Institute Affiliations

Carver Family Center for Macular Degeneration
Stephen A. Wynn Institute for Vision Research

All Publications

Stasheff S, Shankar M, Andrews M.  Developmental time course distinguishes changes in spontaneous and light-evoked retinal ganglion cell activity in rd1 and rd10 mice.  Journal of Neurophysiology.  2011. 105(6):3002-9.
[Link]

Thompson S, Stasheff S, Hernandez J, Nylen E, East J, Kardon R, Pinto L, Mullins R, Stone E.  Different inner retinal pathways mediate rod-cone input in irradiance detection for the pupillary light reflex and regulation of behavioral state in mice.  Invest Ophthalmol Vis Sci.  2011. 52(1):618-23.
[Link]

Abu-El-Haija M, Stasheff S, Atkins D, Bishop W.  Rheumatic fever in a patient receiving infliximab therapy for Crohn disease.  Journal of pediatric gastroenterology and nutrition.  2011. 52(3):306-1.
[Link]

Stasheff S.  Emergence of sustained spontaneous hyperactivity and temporary preservation of OFF responses in ganglion cells of the retinal degeneration (rd1) mouse.  Journal of Neurophysiology.  2008. 99(3):1408-21.
[Link]

Murtha T, Stasheff S.  Visual dysfunction in retinal and optic nerve disease.  Neurologic Clinics.  2003. 21(2):445-81.
[Link]

Stasheff S, Masland R.  Functional inhibition in direction-selective retinal ganglion cells: spatiotemporal extent and intralaminar interactions.  Journal of Neurophysiology.  2002. 88(2):1026-39.
[Link]

Jeon C, Kong J, Strettoi E, Rockhill R, Stasheff S, Masland R.  Pattern of synaptic excitation and inhibition upon direction-selective retinal ganglion cells.  Journal of comparative neurology.  2002. 449(2):195-205.
[Link]

Stasheff S, Barton J.  Deficits in cortical visual function.  Ophthalmol Clin North Am.  2001. 14(1):217-42.
[Link]

Burack M, Stasheff S, Wilson W.  Selective suppression of in vitro electrographic seizures by low-dose tetrodotoxin: a novel anticonvulsant effect.  Epilepsy research.  1995. 22(2):115-26.
[Link]

Stasheff S, Hines M, Wilson W.  Axon terminal hyperexcitability associated with epileptogenesis in vitro. I. Origin of ectopic spikes.  Journal of Neurophysiology.  1993. 70(3):961-75.
[Link]

Stasheff S, Mott D, Wilson W.  Axon terminal hyperexcitability associated with epileptogenesis in vitro. II. Pharmacological regulation by NMDA and GABAA receptors.  Journal of Neurophysiology.  1993. 70(3):976-84.
[Link]

Stasheff S, Wilson W.  Axon terminal hyperexcitability seen in epileptogenesis in vitro.  Ion channels.  1992. 3:137-57.
[Link]

Stasheff S, Wilson W.  The genesis of seizures in vitro: axon terminal excitability.  Epilepsy research Supplement.  1992. 9:319-30.
[Link]

Wilson W, Stasheff S, Swartzwelder S, Clark S, Anderson W.  The role of NMDA receptors in in vitro epileptogenesis.  Epilepsy research Supplement.  1992. 8:157-66.
[Link]

Stasheff S, Wilson W.  Increased ectopic action potential generation accompanies epileptogenesis in vitro.  Neuroscience letters.  1990. 111(1-2):144-50.
[Link]

Anderson W, Stasheff S, Swartzwelder H, Wilson W.  Regenerative, all-or-none electrographic seizures in the rat hippocampal slice in Mg-free and physiological medium.  Brain research.  1990. 532(1-2):288-98.
[Link]

Stasheff S, Anderson W, Clark S, Wilson W.  NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.  Science (New York, NY).  1989. 245(4918):648-51.
[Link]

Slotkin T, Levant B, Orband-Miller L, Queen K, Stasheff S.  Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins.  Journal of pharmacology and experimental therapeutics.  1988. 244(1):166-72.
[Link]

Stasheff S, Bragdon A, Wilson W.  Induction of epileptiform activity in hippocampal slices by trains of electrical stimuli.  Brain research.  1985. 344(2):296-302.
[Link]

Date Last Modified: 06/07/2014 - 21:56:23