Martin & Ruth Carver Chair in Genetics
Investigator, Howard Hughes Medical Institute
Director, Division of Medical Genetics
Director, Interdepartmental Research Program in Human Molecular Genetics
Professor of Pediatrics
- Medical Genetics
Professor of
Ophthalmology and Visual Sciences
Contact Information
Lab: 4181 MERF
Iowa City, IA 52242
Phone: 319-335-6898
Email: val-sheffield@uiowa.edu
Education
BS, Zoology, Brigham Young University, Provo, Utah
MS, Developmental Biology, Brigham Young University, Provo, Utah
PhD, Developmental Biology, University of Chicago, Chicago, Illinois
MD, Medicine, with Honors, University of Chicago, Chicago, Illinois
Residency, Pediatrics, University of California, San Francisco, California
Fellowship, Medical Genetics, University of California, San Francisco, California
Licensure and Certifications
Permanent Iowa license to practice medicine and surgery
Board certified in Clinical Molecular Genetics
Board certified in Clinical Medical Genetics
Diplomate of the National Board of Medical Examiners
Education/Training Program Affiliations
Biosciences Graduate Program
Interdisciplinary Graduate Program in Genetics
Interdisciplinary Graduate Program in Informatics
Interdisciplinary Graduate Program in Neuroscience
Interdisciplinary Graduate Program in Translational Biomedicine
Medical Scientist Training Program
Research Summary
My laboratory is interested in identifying and understanding the function of genes which cause a variety of human disorders. Our research efforts have focused on the molecular genetics of monogenic disorders, as well as polygenic and multifactorial disorders. Our research efforts have resulted in the mapping of many different disease loci. In addition, we have used positional cloning methods to identify genes involved in a number of different diseases including hereditary blindness and deafness. Efforts are currently underway to use positional cloning strategies to identify additional disease-causing genes. Complex genetic disorders currently under investigation in the laboratory include hypertension, obesity, congenital heart disease and autism. In addition, we have worked on developing and improving techniques for disease mapping, positional cloning, and mutation detection. We have also had an active role in the human genome project and the rat genome project.
Date Last Modified: 03/08/2013 -
10:26:34