Stead Family Department of Pediatrics

Michael Shy, MD

Portrait

Attending Neurologist
Specialty: Neuromuscular Disease
Director, Division of Neuromuscular Medicine, Neurology
Professor of Neurology
Professor of Pediatrics, Molecular Physiology and Biophysics

Contact Information

Office: 2157 RCP
Iowa City, IA 52242
Phone: 319-384-5094

Email: michael-shy@uiowa.edu

Education

BA, History, University of Pennsylvania
MD, Medicine, Albany Medical College

Internship, Internal Medicine, Albany Medical Center
Residency, Columbia Presbyterian Medical Center
Fellowship, Clinical Neuroscience Training Program, Columbia Presbyterian Medical Center
Fellowship, Neuroimmunology, Muscular Dystrophy Association

Licensure and Certifications

Iowa MD license
Michigan MD license
Board Certified in Neurology

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Neuroscience

Research Summary

My professional interests involve translational research to develop rational therapies for patients with inherited peripheral neuropathies and related neurodegenerative diseases.

All Publications

Jerath N, Kamholz J, Grider T, Harper A, Swenson A, Shy M.  Coexistence of a T118M PMP22 missense mutation and chromosome 17 (17p11.2-p12) deletion..  Muscle & nerve.  2015 November 1. 52(5):905-8.
[PubMed]

Sanmaneechai O, Feely S, Scherer S, Herrmann D, Burns J, Muntoni F, Li  J, Siskind C, Day J, Laura M, Sumner C, Lloyd T, Ramchandren S, Shy R, Grider T, Bacon C, Finkel R, Yum S, Moroni I, Piscosquito G, Pareyson D, Reilly M, Shy M.  Genotype-phenotype characteristics and baseline natural history of heritable neuropathies caused by mutations in the MPZ gene..  Brain : a journal of neurology.  2015 November 1. 138(Pt 11):3180-92.
[PubMed]

Manganelli F, Nolano M, Pisciotta C, Provitera V, Fabrizi G, Cavallaro T, Stancanelli A, Caporaso G, Shy M, Santoro L.  Charcot-Marie-Tooth disease: New insights from skin biopsy..  Neurology.  2015 October 6. 85(14):1202-8.
[PubMed]

Brennan K, Bai Y, Pisciotta C, Wang S, Feely S, Hoegger M, Gutmann L, Moore S, Gonzalez M, Sherman D, Brophy P, Züchner S, Shy M.  Absence of Dystrophin Related Protein-2 disrupts Cajal bands in a patient with Charcot-Marie-Tooth disease..  Neuromuscular disorders : NMD.  2015 October 1. 25(10):786-93.
[PubMed]

Gutmann L, Shy M.  Update on Charcot-Marie-Tooth disease..  Current opinion in neurology.  2015 October 1. 28(5):462-7.
[PubMed]

Strickland A, Schabhüttl M, Offenbacher H, Synofzik M, Hauser N, Brunner-Krainz M, Gruber-Sedlmayr U, Moore S, Windhager R, Bender B, Harms M, Klebe S, Young P, Kennerson M, Garcia A, Gonzalez M, Züchner S, Schule R, Shy M, Auer-Grumbach M.  Mutation screen reveals novel variants and expands the phenotypes associated with DYNC1H1..  Journal of neurology.  2015 September 1. 262(9):2124-34.
[PubMed]

Gonzaga-Jauregui C, Harel T, Gambin T, Kousi M, Griffin L, Francescatto L, Ozes B, Karaca E, Jhangiani S, Bainbridge M, Lawson K, Pehlivan D, Okamoto Y, Withers M, Mancias P, Slavotinek A, Reitnauer P, Goksungur M, Shy M, Crawford T, Koenig M, Willer J, Flores B, Pediaditrakis I, Us O, Wiszniewski W, Parman Y, Antonellis A, Muzny D, Katsanis N, Battaloglu E, Boerwinkle E, Gibbs R, Lupski J.  Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy..  Cell reports.  2015 August 18. 12(7):1169-83.
[PubMed]

Fridman V, Bundy B, Reilly M, Pareyson D, Bacon C, Burns J, Day J, Feely S, Finkel R, Grider T, Kirk C, Herrmann D, Laurá M, Li  J, Lloyd T, Sumner C, Muntoni F, Piscosquito G, Ramchandren S, Shy R, Siskind C, Yum S, Moroni I, Pagliano E, Zuchner S, Scherer S, Shy M.  CMT subtypes and disease burden in patients enrolled in the Inherited Neuropathies Consortium natural history study: a cross-sectional analysis..  Journal of neurology, neurosurgery, and psychiatry.  2015 August 1. 86(8):873-8.
[PubMed]

Pisciotta C, Bai Y, Brennan K, Wu X, Grider T, Feely S, Wang S, Moore S, Siskind C, Gonzalez M, Zuchner S, Shy M.  Reduced neurofilament expression in cutaneous nerve fibers of patients with CMT2E..  Neurology.  2015 July 21. 85(3):228-34.
[PubMed]

Jerath N, Shy M, Grider T, Gutmann L.  A case of neuromyotonia and axonal motor neuropathy: A report of a HINT 1 mutation in the United States..  Muscle & nerve.  2015 July 16. 
[PubMed]

Brennan K, Bai Y, Shy M.  Demyelinating CMT--what's known, what's new and what's in store?.  Neuroscience letters.  2015 June 2. 596:14-26.
[PubMed]

Ramchandren S, Shy M, Feldman E, Carlos R, Siskind C.  Defining disability: development and validation of a mobility-Disability Severity Index (mDSI) in Charcot-Marie-tooth disease..  Journal of neurology, neurosurgery, and psychiatry.  2015 June 1. 86(6):635-9.
[PubMed]

Jerath N, Shy M.  Hereditary motor and sensory neuropathies: Understanding molecular pathogenesis could lead to future treatment strategies..  Biochimica et biophysica acta.  2015 April 1. 1852(4):667-78.
[PubMed]

Sanmaneechai O, Swenson A, Gerke A, Moore S, Shy M.  Inclusion body myositis and sarcoid myopathy: coincidental occurrence or associated diseases..  Neuromuscular disorders : NMD.  2015 April 1. 25(4):297-300.
[PubMed]

Johnson N, Sowden J, Dilek N, Eichinger K, Burns J, Mcdermott M, Shy M, Herrmann D.  Prospective study of muscle cramps in Charcot-Marie-tooth disease..  Muscle & nerve.  2015 April 1. 51(4):485-8.
[PubMed]

Shy M.  Ultrasound: the future for evaluating the PNS in humans?.  Journal of neurology, neurosurgery, and psychiatry.  2015 April 1. 86(4):362.
[PubMed]

Parker B, Alexander R, Wu X, Feely S, Shy M, Schnetz-Boutaud N, Li  J.  Detection of copy number variation by SNP-allelotyping..  Journal of neurogenetics.  2015 March 1. 29(1):4-7.
[PubMed]

Nolano M, Manganelli F, Provitera V, Pisciotta C, Stancanelli A, Caporaso G, Iodice R, Shy M, Santoro L.  Small nerve fiber involvement in CMT1A..  Neurology.  2015 January 27. 84(4):407-14.
[PubMed]

Saporta M, Dang V, Volfson D, Zou B, Xie X, Adebola A, Liem R, Shy M, Dimos J.  Axonal Charcot-Marie-Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties..  Experimental neurology.  2015 January 1. 263:190-9.
[PubMed]

Jerath N, Crockett C, Moore S, Shy M, Weihl C, Chou T, Grider T, Gonzalez M, Zuchner S, Swenson A.  Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation..  Case reports in genetics.  2015 January 1. 2015:239167.
[PubMed]

Gonzalez M, Feely S, Speziani F, Strickland A, Danzi M, Bacon C, Lee Y, Chou T, Blanton S, Weihl C, Zuchner S, Shy M.  A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease..  Brain : a journal of neurology.  2014 November 1. 137(Pt 11):2897-902.
[PubMed]

Johnson N, Heatwole C, Dilek N, Sowden J, Kirk C, Shereff D, Shy M, Herrmann D.  Quality-of-life in Charcot-Marie-Tooth disease: the patient's perspective..  Neuromuscular disorders : NMD.  2014 November 1. 24(11):1018-23.
[PubMed]

Mannil M, Solari A, Leha A, Pelayo-Negro A, Berciano J, Schlotter-Weigel B, Walter M, Rautenstrauss B, Schnizer T, Schenone A, Seeman P, Kadian C, Schreiber O, Angarita N, Fabrizi G, Gemignani F, Padua L, Santoro L, Quattrone A, Vita G, Calabrese D, Young P, Laurà M, Haberlová J, Mazanec R, Paulus W, Beissbarth T, Shy M, Reilly M, Pareyson D, Sereda M.  Selected items from the Charcot-Marie-Tooth (CMT) Neuropathy Score and secondary clinical outcome measures serve as sensitive clinical markers of disease severity in CMT1A patients..  Neuromuscular disorders : NMD.  2014 November 1. 24(11):1003-17.
[PubMed]

Shy M, Fung S, Boone T, Karmonik C, Fletcher S, Khavari R.  Functional magnetic resonance imaging during urodynamic testing identifies brain structures initiating micturition..  The Journal of urology.  2014 October 1. 192(4):1149-54.
[PubMed]

Brewer M, Ma K, Beecham G, Gopinath C, Baas F, Choi B, Reilly M, Shy M, Züchner S, Svaren J, Antonellis A.  Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2..  Human molecular genetics.  2014 October 1. 23(19):5171-87.
[PubMed]

Sadjadi R, Reilly M, Shy M, Pareyson D, Laura M, Murphy S, Feely S, Grider T, Bacon C, Piscosquito G, Calabrese D, Burns T.  Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis..  Journal of the peripheral nervous system : JPNS.  2014 September 1. 19(3):192-6.
[PubMed]

Tousignant R, Trepanier A, Shy M, Siskind C.  Genetic testing practices for Charcot-Marie-Tooth type 1A disease..  Muscle & nerve.  2014 April 1. 49(4):478-82.
[PubMed]

Ramchandren S, Jaiswal M, Feldman E, Shy M.  Effect of pain in pediatric inherited neuropathies..  Neurology.  2014 March 4. 82(9):793-7.
[PubMed]

Eschbach J, Sinniger J, Bouitbir J, Fergani A, Schlagowski A, Zoll J, Geny B, René F, Larmet Y, Marion V, Baloh R, Harms M, Shy M, Messadeq N, Weydt P, Loeffler J, Ludolph A, Dupuis L.  Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age..  Neurobiology of disease.  2013 October 1. 58:220-30.
[PubMed]

Klein C, Duan X, Shy M.  Inherited neuropathies: clinical overview and update..  Muscle & nerve.  2013 October 1. 48(4):604-22.
[PubMed]

Nobile-Orazio E, Léger J, Lewis R, Bolino A, Shy M, Cornblath D.  Meeting report: 2013 Peripheral Nerve Society Biennial Meeting, Saint-Malo, France, June 29-July 3, 2013..  Journal of the peripheral nervous system : JPNS.  2013 September 1. 18(3):197-8.
[PubMed]

Lewis R, McDermott M, Herrmann D, Hoke A, Clawson L, Siskind C, Feely S, Miller L, Barohn R, Smith P, Luebbe E, Wu X, Shy M.  High-dosage ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A: results of a randomized, double-masked, controlled trial..  JAMA neurology.  2013 August 1. 70(8):981-7.
[PubMed]

Burns J, Menezes M, Finkel R, Estilow T, Moroni I, Pagliano E, Laurá M, Muntoni F, Herrmann D, Eichinger K, Shy R, Pareyson D, Reilly M, Shy M.  Transitioning outcome measures: relationship between the CMTPedS and CMTNSv2 in children, adolescents, and young adults with Charcot-Marie-Tooth disease..  Journal of the peripheral nervous system : JPNS.  2013 June 1. 18(2):177-80.
[PubMed]

Saporta M, Shy M.  Inherited peripheral neuropathies..  Neurologic clinics.  2013 May 1. 31(2):597-619.
[PubMed]

Komyathy K, Neal S, Feely S, Miller L, Lewis R, Trigge G, Siskind C, Shy M, Ramchandren S.  Anterior tibialis CMAP amplitude correlations with impairment in CMT1A..  Muscle & nerve.  2013 April 1. 47(4):493-6.
[PubMed]

Shy M, Fletcher S.  Objective Evaluation of Overactive Bladder: Which Surveys Should I Use?.  Current bladder dysfunction reports.  2013 March 1. 8(1):45-50.
[PubMed]

Bai Y, Patzko A, Shy M.  Unfolded protein response, treatment and CMT1B..  Rare diseases (Austin, Tex.).  2013 January 1. 1:e24049.
[PubMed]

Patzkó A, Bai Y, Saporta M, Katona I, Wu X, Vizzuso D, Feltri M, Wang S, Dillon L, Kamholz J, Kirschner D, Sarkar F, Wrabetz L, Shy M.  Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice..  Brain : a journal of neurology.  2012 December 1. 135(Pt 12):3551-66.
[PubMed]

Eisenberg M, Shy M, Herder D, Walters R, Lipshultz L.  The relationship between anogenital distance and the efficacy of varicocele repair..  BJU international.  2012 December 1. 110(11 Pt C):E927-30.
[PubMed]

Eisenberg M, Shy M, Walters R, Lipshultz L.  The relationship between anogenital distance and azoospermia in adult men..  International journal of andrology.  2012 October 1. 35(5):726-30.
[PubMed]

Shy M.  Lessons from London..  Journal of neurology, neurosurgery, and psychiatry.  2012 August 1. 83(8):767-8.
[PubMed]

Burns J, Ouvrier R, Estilow T, Shy R, Laurá M, Eichinger K, Muntoni F, Reilly M, Pareyson D, Acsadi G, Shy M, Finkel R.  Symmetry of foot alignment and ankle flexibility in paediatric Charcot-Marie-Tooth disease..  Clinical biomechanics (Bristol, Avon).  2012 August 1. 27(7):744-7.
[PubMed]

Saporta M, Shy B, Patzko A, Bai Y, Pennuto M, Ferri C, Tinelli E, Saveri P, Kirschner D, Crowther M, Southwood C, Wu X, Gow A, Feltri M, Wrabetz L, Shy M.  MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot-Marie-Tooth disease type 1B..  Brain : a journal of neurology.  2012 July 1. 135(Pt 7):2032-47.
[PubMed]

Murphy S, Ovens R, Polke J, Siskind C, Laurà M, Bull K, Ramdharry G, Houlden H, Murphy R, Shy M, Reilly M.  X inactivation in females with X-linked Charcot-Marie-Tooth disease..  Neuromuscular disorders : NMD.  2012 July 1. 22(7):617-21.
[PubMed]

Miller L, Patzko A, Lewis R, Shy M.  Phenotypic presentation of the Ser63Del MPZ mutation..  Journal of the peripheral nervous system : JPNS.  2012 June 1. 17(2):197-200.
[PubMed]

Harms M, Ori-McKenney K, Scoto M, Tuck E, Bell S, Ma D, Masi S, Allred P, Al-Lozi M, Reilly M, Miller L, Jani-Acsadi A, Pestronk A, Shy M, Muntoni F, Vallee R, Baloh R.  Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy..  Neurology.  2012 May 29. 78(22):1714-20.
[PubMed]

Burns J, Ouvrier R, Estilow T, Shy R, Laurá M, Pallant J, Lek M, Muntoni F, Reilly M, Pareyson D, Acsadi G, Shy M, Finkel R.  Validation of the Charcot-Marie-Tooth disease pediatric scale as an outcome measure of disability..  Annals of neurology.  2012 May 1. 71(5):642-52.
[PubMed]

Prada V, Passalacqua M, Bono M, Luzzi P, Scazzola S, Nobbio L, Capponi S, Bellone E, Mandich P, Mancardi G, Shy M, Schenone A, Grandis M.  Gain of glycosylation: a new pathomechanism of myelin protein zero mutations..  Annals of neurology.  2012 March 1. 71(3):427-31.
[PubMed]

Patzko A, Shy M.  Charcot-Marie-Tooth disease and related genetic neuropathies..  Continuum (Minneapolis, Minn.).  2012 February 1. 18(1):39-59.
[PubMed]

Siskind C, Shy M.  Genetics of neuropathies..  Seminars in neurology.  2011 November 1. 31(5):494-505.
[PubMed]

Shy M, Patzkó A.  Axonal Charcot-Marie-Tooth disease..  Current opinion in neurology.  2011 October 1. 24(5):475-83.
[PubMed]

Miller L, Saporta A, Sottile S, Siskind C, Feely S, Shy M.  Strategy for genetic testing in Charcot-Marie-disease..  Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology / edited by the Gaetano Conte Academy for the study of striated muscle diseases.  2011 October 1. 30(2):109-16.
[PubMed]

Almodovar J, Ferguson M, McDermott M, Lewis R, Shy M, Herrmann D.  In vivo confocal microscopy of Meissner corpuscles as a novel sensory measure in CMT1A..  Journal of the peripheral nervous system : JPNS.  2011 September 1. 16(3):169-74.
[PubMed]

Murphy S, Herrmann D, McDermott M, Scherer S, Shy M, Reilly M, Pareyson D.  Reliability of the CMT neuropathy score (second version) in Charcot-Marie-Tooth disease..  Journal of the peripheral nervous system : JPNS.  2011 September 1. 16(3):191-8.
[PubMed]

Saporta M, Katona I, Zhang X, Roper H, McClelland L, Macdonald F, Brueton L, Blake J, Suter U, Reilly M, Shy M, Li  J.  Neuropathy in a human without the PMP22 gene..  Archives of neurology.  2011 June 1. 68(6):814-21.
[PubMed]

Siskind C, Murphy S, Ovens R, Polke J, Reilly M, Shy M.  Phenotype expression in women with CMT1X..  Journal of the peripheral nervous system : JPNS.  2011 June 1. 16(2):102-7.
[PubMed]

Feely S, Laura M, Siskind C, Sottile S, Davis M, Gibbons V, Reilly M, Shy M.  MFN2 mutations cause severe phenotypes in most patients with CMT2A..  Neurology.  2011 May 17. 76(20):1690-6.
[PubMed]

Katona I, Zhang X, Bai Y, Shy M, Guo J, Yan Q, Hatfield J, Kupsky W, Li  J.  Distinct pathogenic processes between Fig4-deficient motor and sensory neurons..  The European journal of neuroscience.  2011 April 1. 33(8):1401-10.
[PubMed]

Shy M.  Inherited peripheral neuropathies..  Continuum (Minneapolis, Minn.).  2011 April 1. 17(2 Neurogenetics):294-315.
[PubMed]

Montenegro G, Powell E, Huang J, Speziani F, Edwards Y, Beecham G, Hulme W, Siskind C, Vance J, Shy M, Züchner S.  Exome sequencing allows for rapid gene identification in a Charcot-Marie-Tooth family..  Annals of neurology.  2011 March 1. 69(3):464-70.
[PubMed]

Patzkó A, Shy M.  Update on Charcot-Marie-Tooth disease..  Current neurology and neuroscience reports.  2011 February 1. 11(1):78-88.
[PubMed]

Saporta A, Sottile S, Miller L, Feely S, Siskind C, Shy M.  Charcot-Marie-Tooth disease subtypes and genetic testing strategies..  Annals of neurology.  2011 January 1. 69(1):22-33.
[PubMed]

Reilly M, Shy M, Muntoni F, Pareyson D.  168th ENMC International Workshop: outcome measures and clinical trials in Charcot-Marie-Tooth disease (CMT)..  Neuromuscular disorders : NMD.  2010 December 1. 20(12):839-46.
[PubMed]

Lin C, Lin S, Yang Y, Shih J, Shy M, Lee C, Yang Y.  Extremely preterm cesarean delivery "en caul"..  Taiwanese journal of obstetrics & gynecology.  2010 September 1. 49(3):254-9.
[PubMed]

Burns J, Ramchandren S, Ryan M, Shy M, Ouvrier R.  Determinants of reduced health-related quality of life in pediatric inherited neuropathies..  Neurology.  2010 August 24. 75(8):726-31.
[PubMed]

Shy M.  MUNE and progression of CMT1A..  European journal of neurology : the official journal of the European Federation of Neurological Societies.  2010 August 1. 17(8):997-8.
[PubMed]

Huang J, Wu X, Montenegro G, Price J, Wang G, Vance J, Shy M, Züchner S.  Copy number variations are a rare cause of non-CMT1A Charcot-Marie-Tooth disease..  Journal of neurology.  2010 May 1. 257(5):735-41.
[PubMed]

Kennerson M, Nicholson G, Kaler S, Kowalski B, Mercer J, Tang J, Llanos R, Chu S, Takata R, Speck-Martins C, Baets J, Almeida-Souza L, Fischer D, Timmerman V, Taylor P, Scherer S, Ferguson T, Bird T, De Jonghe P, Feely S, Shy M, Garbern J.  Missense mutations in the copper transporter gene ATP7A cause X-linked distal hereditary motor neuropathy..  American journal of human genetics.  2010 March 12. 86(3):343-52.
[PubMed]

Bai Y, Zhang X, Katona I, Saporta M, Shy M, O'Malley H, Isom L, Suter U, Li  J.  Conduction block in PMP22 deficiency..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  2010 January 13. 30(2):600-8.
[PubMed]

Huang S, Chen H, Ma K, Shy M, Chen J, Lin W, Lu R.  Association of promoter variants of human dopamine transporter gene with schizophrenia in Han Chinese..  Schizophrenia research.  2010 January 1. 116(1):68-74.
[PubMed]

Reilly M, Shy M.  Diagnosis and new treatments in genetic neuropathies..  Journal of neurology, neurosurgery, and psychiatry.  2009 December 1. 80(12):1304-14.
[PubMed]

Saporta M, Katona I, Lewis R, Masse S, Shy M, Li  J.  Shortened internodal length of dermal myelinated nerve fibres in Charcot-Marie-Tooth disease type 1A..  Brain : a journal of neurology.  2009 December 1. 132(Pt 12):3263-73.
[PubMed]

Ramchandren S, Shy M, Finkel R.  Quality of life in children with CMT type 1A..  The Lancet. Neurology.  2009 October 1. 8(10):880-1; author reply 881.
[PubMed]

Katona I, Wu X, Feely S, Sottile S, Siskind C, Miller L, Shy M, Li  J.  PMP22 expression in dermal nerve myelin from patients with CMT1A..  Brain : a journal of neurology.  2009 July 1. 132(Pt 7):1734-40.
[PubMed]

Shy M.  Ascorbic acid for treatment of CMT1A: the jury is still out..  The Lancet. Neurology.  2009 June 1. 8(6):505-7.
[PubMed]

Siskind C, Feely S, Bernes S, Shy M, Garbern J.  Persistent CNS dysfunction in a boy with CMT1X..  Journal of the neurological sciences.  2009 April 15. 279(1-2):109-13.
[PubMed]

Kennerson M, Nicholson G, Kowalski B, Krajewski K, El-Khechen D, Feely S, Chu S, Shy M, Garbern J.  X-linked distal hereditary motor neuropathy maps to the DSMAX locus on chromosome Xq13.1-q21..  Neurology.  2009 January 20. 72(3):246-52.
[PubMed]

Huang S, Lin M, Lin W, Huang C, Shy M, Lu R.  Association of monoamine oxidase A (MAOA) polymorphisms and clinical subgroups of major depressive disorders in the Han Chinese population..  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.  2009 January 1. 10(4 Pt 2):544-51.
[PubMed]

Shy M.  Biology of peripheral inherited neuropathies: Schwann cell axonal interactions..  Advances in experimental medicine and biology.  2009 January 1. 652:171-81.
[PubMed]

Chang H, Lu R, Shy M, Chang C, Lee M, Huang S.  Brain-derived neurotrophic factor Val66Met polymorphism: association with psychopathological symptoms of schizophrenia?.  The Journal of neuropsychiatry and clinical neurosciences.  2009 January 1. 21(1):30-7.
[PubMed]

Nicholson G, Kennerson M, Brewer M, Garbern J, Shy M.  Genotypes & sensory phenotypes in 2 new X-linked neuropathies (CMTX3 and dSMAX) and dominant CMT/HMN overlap syndromes..  Advances in experimental medicine and biology.  2009 January 1. 652:201-6.
[PubMed]

Sheth S, Francies K, Siskind C, Feely S, Lewis R, Shy M.  Diabetes mellitus exacerbates motor and sensory impairment in CMT1A..  Journal of the peripheral nervous system : JPNS.  2008 December 1. 13(4):299-304.
[PubMed]

Gooch C, Shy M.  Hereditary motor neuropathy and heat shock proteins: a shocking transformation..  Neurology.  2008 November 18. 71(21):1656-7.
[PubMed]

Huang S, Lin M, Shy M, Lin W, Lin F, Lu R.  Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder..  European archives of psychiatry and clinical neuroscience.  2008 September 1. 258(6):350-6.
[PubMed]

Chung K, Suh B, Shy M, Cho S, Yoo J, Park S, Moon H, Park K, Choi K, Kim S, Kim S, Shim D, Kim S, Sunwoo I, Choi B.  Different clinical and magnetic resonance imaging features between Charcot-Marie-Tooth disease type 1A and 2A..  Neuromuscular disorders : NMD.  2008 August 1. 18(8):610-8.
[PubMed]

Zhang X, Chow C, Sahenk Z, Shy M, Meisler M, Li  J.  Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration..  Brain : a journal of neurology.  2008 August 1. 131(Pt 8):1990-2001.
[PubMed]

Grandis M, Vigo T, Passalacqua M, Jain M, Scazzola S, La Padula V, Brucal M, Benvenuto F, Nobbio L, Cadoni A, Mancardi G, Kamholz J, Shy M, Schenone A.  Different cellular and molecular mechanisms for early and late-onset myelin protein zero mutations..  Human molecular genetics.  2008 July 1. 17(13):1877-89.
[PubMed]

Shy M.  Obstructive sleep apnoea and CMT1A: answers and more questions..  Journal of neurology, neurosurgery, and psychiatry.  2008 July 1. 79(7):743-4.
[PubMed]

Jani-Acsadi A, Krajewski K, Shy M.  Charcot-Marie-Tooth neuropathies: diagnosis and management..  Seminars in neurology.  2008 April 1. 28(2):185-94.
[PubMed]

Padua L, Shy M, Aprile I, Cavallaro T, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, Schenone A.  Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A..  Journal of the peripheral nervous system : JPNS.  2008 March 1. 13(1):64-70.
[PubMed]

Shy M, Chakrabarti S, Gintzler A.  Plasticity of adenylyl cyclase-related signaling sequelae after long-term morphine treatment..  Molecular pharmacology.  2008 March 1. 73(3):868-79.
[PubMed]

Shy M, Chen L, Swan E, Taube R, Krajewski K, Herrmann D, Lewis R, McDermott M.  Neuropathy progression in Charcot-Marie-Tooth disease type 1A..  Neurology.  2008 January 29. 70(5):378-83.
[PubMed]

Huang S, Lu R, Ma K, Shy M, Lin W.  Norepinephrine transporter polymorphisms T-182C and G1287A are not associated with alcohol dependence and its clinical subgroups..  Drug and alcohol dependence.  2008 January 1. 92(1-3):20-6.
[PubMed]

Kim H, Sohn K, Shy M, Krajewski K, Hwang M, Park J, Jang S, Won H, Choi B, Hong S, Kim B, Suh Y, Ki C, Lee S, Kim S, Kim J.  Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic neuropathy (cmtx5)..  American journal of human genetics.  2007 September 1. 81(3):552-8.
[PubMed]

Chow C, Zhang Y, Dowling J, Jin N, Adamska M, Shiga K, Szigeti K, Shy M, Li  J, Zhang X, Lupski J, Weisman L, Meisler M.  Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J..  Nature.  2007 July 5. 448(7149):68-72.
[PubMed]

Li  J, Ghandour K, Radovanovic D, Shy R, Krajewski K, Shy M, Nicholson G.  Stoichiometric alteration of PMP22 protein determines the phenotype of hereditary neuropathy with liability to pressure palsies..  Archives of neurology.  2007 July 1. 64(7):974-8.
[PubMed]

Gaboreanu A, Hrstka R, Xu W, Shy M, Kamholz J, Lilien J, Balsamo J.  Myelin protein zero/P0 phosphorylation and function require an adaptor protein linking it to RACK1 and PKC alpha..  The Journal of cell biology.  2007 May 21. 177(4):707-16.
[PubMed]

Shy M, Siskind C, Swan E, Krajewski K, Doherty T, Fuerst D, Ainsworth P, Lewis R, Scherer S, Hahn A.  CMT1X phenotypes represent loss of GJB1 gene function..  Neurology.  2007 March 13. 68(11):849-55.
[PubMed]

Swan E, Fuerst D, Shy M.  Women and men are equally disabled by Charcot-Marie-Tooth disease type 1A..  Neurology.  2007 March 13. 68(11):873.
[PubMed]

Aboussouan L, Lewis R, Shy M.  Disorders of pulmonary function, sleep, and the upper airway in Charcot-Marie-Tooth disease..  Lung.  2007 January 1. 185(1):1-7.
[PubMed]

Bai Y, Ianokova E, Pu Q, Ghandour K, Levinson R, Martin J, Ceuterick-de Groote C, Mazanec R, Seeman P, Shy M, Li  J.  Effect of an R69C mutation in the myelin protein zero gene on myelination and ion channel subtypes..  Archives of neurology.  2006 December 1. 63(12):1787-94.
[PubMed]

Sabet A, Li  J, Ghandour K, Pu Q, Wu X, Kamholz J, Shy M, Cambi F.  Skin biopsies demonstrate MPZ splicing abnormalities in Charcot-Marie-Tooth neuropathy 1B..  Neurology.  2006 October 10. 67(7):1141-6.
[PubMed]

Stanton M, Pannoni V, Lewis R, Logigian E, Naguib D, Shy M, Cleland J, Herrmann D.  Dispersion of compound muscle action potential in hereditary neuropathies and chronic inflammatory demyelinating polyneuropathy..  Muscle & nerve.  2006 October 1. 34(4):417-22.
[PubMed]

Li  J, Bai Y, Ianakova E, Grandis M, Uchwat F, Trostinskaia A, Krajewski K, Garbern J, Kupsky W, Shy M.  Major myelin protein gene (P0) mutation causes a novel form of axonal degeneration..  The Journal of comparative neurology.  2006 September 10. 498(2):252-65.
[PubMed]

Verhoeven K, Claeys K, Züchner S, Schröder J, Weis J, Ceuterick C, Jordanova A, Nelis E, De Vriendt E, Van Hul M, Seeman P, Mazanec R, Saifi G, Szigeti K, Mancias P, Butler I, Kochanski A, Ryniewicz B, De Bleecker J, Van den Bergh P, Verellen C, Van Coster R, Goemans N, Auer-Grumbach M, Robberecht W, Milic Rasic V, Nevo Y, Tournev I, Guergueltcheva V, Roelens F, Vieregge P, Vinci P, Moreno M, Christen H, Shy M, Lupski J, Vance J, De Jonghe P, Timmerman V.  MFN2 mutation distribution and genotype/phenotype correlation in Charcot-Marie-Tooth type 2..  Brain : a journal of neurology.  2006 August 1. 129(Pt 8):2093-102.
[PubMed]

Shy M.  Peripheral neuropathies caused by mutations in the myelin protein zero..  Journal of the neurological sciences.  2006 March 15. 242(1-2):55-66.
[PubMed]

Züchner S, De Jonghe P, Jordanova A, Claeys K, Guergueltcheva V, Cherninkova S, Hamilton S, Van Stavern G, Krajewski K, Stajich J, Tournev I, Verhoeven K, Langerhorst C, de Visser M, Baas F, Bird T, Timmerman V, Shy M, Vance J.  Axonal neuropathy with optic atrophy is caused by mutations in mitofusin 2..  Annals of neurology.  2006 February 1. 59(2):276-81.
[PubMed]

Shy M, Scavina M, Clark A, Krajewski K, Li  J, Kamholz J, Kolodny E, Szigeti K, Fischer R, Saifi G, Scherer S, Lupski J.  T118M PMP22 mutation causes partial loss of function and HNPP-like neuropathy..  Annals of neurology.  2006 February 1. 59(2):358-64.
[PubMed]

Shy M.  Therapeutic strategies for the inherited neuropathies..  Neuromolecular medicine.  2006 January 1. 8(1-2):255-78.
[PubMed]

Shy M, Rose M.  Charcot-Marie-Tooth disease impairs quality of life: why? And how do we improve it?.  Neurology.  2005 September 27. 65(6):790-1.
[PubMed]

Li  J, Bai Y, Ghandour K, Qin P, Grandis M, Trostinskaia A, Ianakova E, Wu X, Schenone A, Vallat J, Kupsky W, Hatfield J, Shy M.  Skin biopsies in myelin-related neuropathies: bringing molecular pathology to the bedside..  Brain : a journal of neurology.  2005 May 1. 128(Pt 5):1168-77.
[PubMed]

Pedrola L, Espert A, Wu X, Claramunt R, Shy M, Palau F.  GDAP1, the protein causing Charcot-Marie-Tooth disease type 4A, is expressed in neurons and is associated with mitochondria..  Human molecular genetics.  2005 April 15. 14(8):1087-94.
[PubMed]

Shy M, Blake J, Krajewski K, Fuerst D, Laura M, Hahn A, Li  J, Lewis R, Reilly M.  Reliability and validity of the CMT neuropathy score as a measure of disability..  Neurology.  2005 April 12. 64(7):1209-14.
[PubMed]

Saifi G, Szigeti K, Wiszniewski W, Shy M, Krajewski K, Hausmanowa-Petrusewicz I, Kochanski A, Reeser S, Mancias P, Butler I, Lupski J.  SIMPLE mutations in Charcot-Marie-Tooth disease and the potential role of its protein product in protein degradation..  Human mutation.  2005 April 1. 25(4):372-83.
[PubMed]

Grandis M, Shy M.  Current Therapy for Charcot-Marie-Tooth Disease..  Current treatment options in neurology.  2005 January 1. 7(1):23-31.
[PubMed]

Shy M.  Charcot-Marie-Tooth disease: an update..  Current opinion in neurology.  2004 October 1. 17(5):579-85.
[PubMed]

Krajewski K, Shy M.  Genetic testing in neuromuscular disease..  Neurologic clinics.  2004 August 1. 22(3):481-508, v.
[PubMed]

Kamholz J, Shy M.  Late onset Charcot-Marie-Tooth 2 syndrome caused by two novel mutations in the MPZ gene..  Neurology.  2004 July 13. 63(1):194; author reply 194.
[PubMed]

Li  J, Krajewski K, Lewis R, Shy M.  Loss-of-function phenotype of hereditary neuropathy with liability to pressure palsies..  Muscle & nerve.  2004 February 1. 29(2):205-10.
[PubMed]

Shy M, Jáni A, Krajewski K, Grandis M, Lewis R, Li  J, Shy R, Balsamo J, Lilien J, Garbern J, Kamholz J.  Phenotypic clustering in MPZ mutations..  Brain : a journal of neurology.  2004 February 1. 127(Pt 2):371-84.
[PubMed]

Lewis R, Li  J, Fuerst D, Shy M, Krajewski K.  Motor unit number estimate of distal and proximal muscles in Charcot-Marie-Tooth disease..  Muscle & nerve.  2003 August 1. 28(2):161-7.
[PubMed]

Li  J, Loeb J, Shy M, Shah A, Tselis A, Kupski W, Lewis R.  Asymmetric flaccid paralysis: a neuromuscular presentation of West Nile virus infection..  Annals of neurology.  2003 June 1. 53(6):703-10.
[PubMed]

Shy M, Frohman E, So Y, Arezzo J, Cornblath D, Giuliani M, Kincaid J, Ochoa J, Parry G, Weimer L.  Quantitative sensory testing: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology..  Neurology.  2003 March 25. 60(6):898-904.
[PubMed]

Jordanova A, De Jonghe P, Boerkoel C, Takashima H, De Vriendt E, Ceuterick C, Martin J, Butler I, Mancias P, Papasozomenos SCh , Terespolsky D, Potocki L, Brown C, Shy M, Rita D, Tournev I, Kremensky I, Lupski J, Timmerman V.  Mutations in the neurofilament light chain gene (NEFL) cause early onset severe Charcot-Marie-Tooth disease..  Brain : a journal of neurology.  2003 March 1. 126(Pt 3):590-7.
[PubMed]

Shy M, Hobson G, Jain M, Boespflug-Tanguy O, Garbern J, Sperle K, Li  W, Gow A, Rodriguez D, Bertini E, Mancias P, Krajewski K, Lewis R, Kamholz J.  Schwann cell expression of PLP1 but not DM20 is necessary to prevent neuropathy..  Annals of neurology.  2003 March 1. 53(3):354-65.
[PubMed]

Paulson H, Garbern J, Hoban T, Krajewski K, Lewis R, Fischbeck K, Grossman R, Lenkinski R, Kamholz J, Shy M.  Transient central nervous system white matter abnormality in X-linked Charcot-Marie-Tooth disease..  Annals of neurology.  2002 October 1. 52(4):429-34.
[PubMed]

Li  J, Krajewski K, Shy M, Lewis R.  Hereditary neuropathy with liability to pressure palsy: the electrophysiology fits the name..  Neurology.  2002 June 25. 58(12):1769-73.
[PubMed]

Acsadi G, Anguelov R, Yang H, Toth G, Thomas R, Jani A, Wang Y, Ianakova E, Mohammad S, Lewis R, Shy M.  Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy..  Human gene therapy.  2002 June 10. 13(9):1047-59.
[PubMed]

Shy M, Garbern J, Kamholz J.  Hereditary motor and sensory neuropathies: a biological perspective..  The Lancet. Neurology.  2002 June 1. 1(2):110-8.
[PubMed]

Salles J, Sargueil F, Knoll-Gellida A, Witters L, Shy M, Jiang H, Cassagne C, Garbay B.  Fatty acid synthase expression during peripheral nervous system myelination..  Brain research. Molecular brain research.  2002 May 30. 101(1-2):52-8.
[PubMed]

Garbern J, Yool D, Moore G, Wilds I, Faulk M, Klugmann M, Nave K, Sistermans E, van der Knaap M, Bird T, Shy M, Kamholz J, Griffiths I.  Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation..  Brain : a journal of neurology.  2002 March 1. 125(Pt 3):551-61.
[PubMed]

Boerkoel C, Takashima H, Garcia C, Olney R, Johnson J, Berry K, Russo P, Kennedy S, Teebi A, Scavina M, Williams L, Mancias P, Butler I, Krajewski K, Shy M, Lupski J.  Charcot-Marie-Tooth disease and related neuropathies: mutation distribution and genotype-phenotype correlation..  Annals of neurology.  2002 February 1. 51(2):190-201.
[PubMed]

Menichella D, Arroyo E, Awatramani R, Xu T, Baron P, Vallat J, Balsamo J, Lilien J, Scarlato G, Kamholz J, Scherer S, Shy M.  Protein zero is necessary for E-cadherin-mediated adherens junction formation in Schwann cells..  Molecular and cellular neurosciences.  2001 December 1. 18(6):606-18.
[PubMed]

Garbern J, Shy M, Krajewski K, Kamholz J, Hobson G, Cambi F.  Evidence for neuroaxonal injury in patients with proteolipid gene mutations..  Neurology.  2001 November 27. 57(10):1938-9.
[PubMed]

Xu W, Shy M, Kamholz J, Elferink L, Xu G, Lilien J, Balsamo J.  Mutations in the cytoplasmic domain of P0 reveal a role for PKC-mediated phosphorylation in adhesion and myelination..  The Journal of cell biology.  2001 October 29. 155(3):439-46.
[PubMed]

Mendell J, Barohn R, Freimer M, Kissel J, King W, Nagaraja H, Rice R, Campbell W, Donofrio P, Jackson C, Lewis R, Shy M, Simpson D, Parry G, Rivner M, Thornton C, Bromberg M, Tandan R, Harati Y, Giuliani M.  Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy..  Neurology.  2001 February 27. 56(4):445-9.
[PubMed]

Shy M, Balsamo J, Lilien J, Kamholz J.  A molecular basis for hereditary motor and sensory neuropathy disorders..  Current neurology and neuroscience reports.  2001 January 1. 1(1):77-88.
[PubMed]

Batourina E, Gim S, Bello N, Shy M, Clagett-Dame M, Srinivas S, Costantini F, Mendelsohn C.  Vitamin A controls epithelial/mesenchymal interactions through Ret expression..  Nature genetics.  2001 January 1. 27(1):74-8.
[PubMed]

Lewis R, Sumner A, Shy M.  Electrophysiological features of inherited demyelinating neuropathies: A reappraisal in the era of molecular diagnosis..  Muscle & nerve.  2000 October 1. 23(10):1472-87.
[PubMed]

Krajewski K, Lewis R, Fuerst D, Turansky C, Hinderer S, Garbern J, Kamholz J, Shy M.  Neurological dysfunction and axonal degeneration in Charcot-Marie-Tooth disease type 1A..  Brain : a journal of neurology.  2000 July 1. 123 ( Pt 7):1516-27.
[PubMed]

Jiang H, Duchala C, Awatramani R, Shumas S, Carlock L, Kamholz J, Garbern J, Scherer S, Shy M, Macklin W.  Proteolipid protein mRNA stability is regulated by axonal contact in the rodent peripheral nervous system..  Journal of neurobiology.  2000 July 1. 44(1):7-19.
[PubMed]

Xu W, Manichella D, Jiang H, Vallat J, Lilien J, Baron P, Scarlato G, Kamholz J, Shy M.  Absence of P0 leads to the dysregulation of myelin gene expression and myelin morphogenesis..  Journal of neuroscience research.  2000 June 15. 60(6):714-24.
[PubMed]

Krajewski K, Shy M.  The neurologist and genetic testing in a neuromuscular clinic..  Journal of clinical neuromuscular disease.  2000 June 1. 1(4):172-4.
[PubMed]

Kamholz J, Menichella D, Jani A, Garbern J, Lewis R, Krajewski K, Lilien J, Scherer S, Shy M.  Charcot-Marie-Tooth disease type 1: molecular pathogenesis to gene therapy..  Brain : a journal of neurology.  2000 February 1. 123 ( Pt 2):222-33.
[PubMed]

Cheng H, Shy M, Feldman E.  Regulation of insulin-like growth factor-binding protein-5 expression during Schwann cell differentiation..  Endocrinology.  1999 October 1. 140(10):4478-85.
[PubMed]

Garbern J, Cambi F, Shy M, Kamholz J.  The molecular pathogenesis of Pelizaeus-Merzbacher disease..  Archives of neurology.  1999 October 1. 56(10):1210-4.
[PubMed]

Krajewski K, Turansky C, Lewis R, Garbern J, Hinderer S, Kamholz J, Shy M.  Correlation between weakness and axonal loss in patients with CMT1A..  Annals of the New York Academy of Sciences.  1999 September 14. 883:490-2.
[PubMed]

Lewis R, Shy M.  Electrodiagnostic findings in CMTX: a disorder of the Schwann cell and peripheral nerve myelin..  Annals of the New York Academy of Sciences.  1999 September 14. 883:504-7.
[PubMed]

Pareyson D, Menichella D, Botti S, Sghirlanzoni A, Fallica E, Mora M, Ciano C, Shy M, Taroni F.  Heterozygous null mutation in the P0 gene associated with mild Charcot-Marie-Tooth disease..  Annals of the New York Academy of Sciences.  1999 September 14. 883:477-80.
[PubMed]

Shy M, Kamholz J, Lovelace R.  Introduction to the Third International Symposium on Charcot-Marie-Tooth disorders..  Annals of the New York Academy of Sciences.  1999 September 14. 883:xiii-xviii.
[PubMed]

Jani A, Menichella D, Jiang H, Chbihi T, Acsadi G, Kamholz J, Shy M.  Overcoming cellular immunity to prolong adenoviral-mediated gene expression in sciatic nerve..  Annals of the New York Academy of Sciences.  1999 September 14. 883:397-414.
[PubMed]

Garbern J, Cambi F, Lewis R, Shy M, Sima A, Kraft G, Vallat J, Bosch E, Hodes M, Dlouhy S, Raskind W, Bird T, Macklin W, Kamholz J.  Peripheral neuropathy caused by proteolipid protein gene mutations..  Annals of the New York Academy of Sciences.  1999 September 14. 883:351-65.
[PubMed]

Kamholz J, Awatramani R, Menichella D, Jiang H, Xu W, Shy M.  Regulation of myelin-specific gene expression. Relevance to CMT1..  Annals of the New York Academy of Sciences.  1999 September 14. 883:91-108.
[PubMed]

Menichella D, Xu W, Jiang H, Sohi J, Vallat J, Baron P, Kamholz J, Shy M.  The absence of myelin P0 protein produces a novel molecular phenotype in Schwann cells..  Annals of the New York Academy of Sciences.  1999 September 14. 883:281-93.
[PubMed]

Jani A, Menichella D, Jiang H, Chbihi T, Acsadi G, Shy M, Kamholz J.  Modulation of cell-mediated immunity prolongs adenovirus-mediated transgene expression in sciatic nerve..  Human gene therapy.  1999 March 20. 10(5):787-800.
[PubMed]

Garbay B, Boiron-Sargueil F, Shy M, Chbihi T, Jiang H, Kamholz J, Cassagne C.  Regulation of oleoyl-CoA synthesis in the peripheral nervous system: demonstration of a link with myelin synthesis..  Journal of neurochemistry.  1998 October 1. 71(4):1719-26.
[PubMed]

Dyck P, Dyck P, Kennedy W, Kesserwani H, Melanson M, Ochoa J, Shy M, Stevens J, Suarez G, O'Brien P.  Limitations of quantitative sensory testing when patients are biased toward a bad outcome..  Neurology.  1998 May 1. 50(5):1213.
[PubMed]

Shy M, Arroyo E, Sladky J, Menichella D, Jiang H, Xu W, Kamholz J, Scherer S.  Heterozygous P0 knockout mice develop a peripheral neuropathy that resembles chronic inflammatory demyelinating polyneuropathy (CIDP)..  Journal of neuropathology and experimental neurology.  1997 July 1. 56(7):811-21.
[PubMed]

Garbern J, Cambi F, Tang X, Sima A, Vallat J, Bosch E, Lewis R, Shy M, Sohi J, Kraft G, Chen K, Joshi I, Leonard D, Johnson W, Raskind W, Dlouhy S, Pratt V, Hodes M, Bird T, Kamholz J.  Proteolipid protein is necessary in peripheral as well as central myelin..  Neuron.  1997 July 1. 19(1):205-18.
[PubMed]

Zaidi Q, Spehar B, Shy M.  Induced effects of backgrounds and foregrounds in three-dimensional configurations: the role of T-junctions..  Perception.  1997 January 1. 26(4):395-408.
[PubMed]

Shy M, Shi Y, Wrabetz L, Kamholz J, Scherer S.  Axon-Schwann cell interactions regulate the expression of c-jun in Schwann cells..  Journal of neuroscience research.  1996 March 1. 43(5):511-25.
[PubMed]

Bird S, Brown M, Shy M, Scherer S.  Chronic inflammatory demyelinating polyneuropathy associated with malignant melanoma..  Neurology.  1996 March 1. 46(3):822-4.
[PubMed]

Shy M, Tani M, Shi Y, Whyatt S, Chbihi T, Scherer S, Kamholz J.  An adenoviral vector can transfer lacZ expression into Schwann cells in culture and in sciatic nerve..  Annals of neurology.  1995 September 1. 38(3):429-36.
[PubMed]

Baron P, Shy M, Kamholz J, Scarlato G, Pleasure D.  Expression of P0 protein mRNA along rat sciatic nerve during development..  Brain research. Developmental brain research.  1994 December 16. 83(2):285-8.
[PubMed]

Kamholz J, Shy M, Scherer S.  Elevated expression of messenger RNA for peripheral myelin protein 22 in biopsied peripheral nerves of patients with Charcot-Marie-Tooth disease type 1A..  Annals of neurology.  1994 September 1. 36(3):451-2.
[PubMed]

Baron P, Shy M, Honda H, Sessa M, Kamholz J, Pleasure D.  Developmental expression of P0 mRNA and P0 protein in the sciatic nerve and the spinal nerve roots of the rat..  Journal of neurocytology.  1994 April 1. 23(4):249-57.
[PubMed]

Heiman-Patterson T, Krupa T, Thompson P, Nobile-Orazio E, Tahmoush A, Shy M.  Anti-GM1/GD1b M-proteins damage human spinal cord neurons co-cultured with muscle..  Journal of the neurological sciences.  1993 December 1. 120(1):38-45.
[PubMed]

Baron P, Kamholz J, Scherer S, Honda H, Shy M, Scarpini E, Scarlato G, Pleasure D.  Appearance of PLP mRNA in specific regions of the developing rat lumbosacral spinal cord as revealed by in situ hybridization..  Experimental neurology.  1993 May 1. 121(1):139-47.
[PubMed]

Feltri M, Scherer S, Wrabetz L, Kamholz J, Shy M.  Mitogen-expanded Schwann cells retain the capacity to myelinate regenerating axons after transplantation into rat sciatic nerve..  Proceedings of the National Academy of Sciences of the United States of America.  1992 September 15. 89(18):8827-31.
[PubMed]

Kamholz J, Sessa M, Scherer S, Vogelbacker H, Mokuno K, Baron P, Wrabetz L, Shy M, Pleasure D.  Structure and expression of proteolipid protein in the peripheral nervous system..  Journal of neuroscience research.  1992 February 1. 31(2):231-44.
[PubMed]

Fishman P, Shy M, Hart D, Thompson P, Cashman N.  Antibodies to the ganglioside GD1b in a patient with motor neuron disease and thyroid adenoma..  Archives of neurology.  1991 November 1. 48(11):1188-90.
[PubMed]

Heiman-Patterson T, Bird S, Parry G, Varga J, Shy M, Culligan N, Edelsohn L, Tatarian G, Heyes M, Garcia C.  Peripheral neuropathy associated with eosinophilia-myalgia syndrome..  Annals of neurology.  1990 October 1. 28(4):522-8.
[PubMed]

Shy M, Heiman-Patterson T, Parry G, Tahmoush A, Evans V, Schick P.  Lower motor neuron disease in a patient with autoantibodies against Gal(beta 1-3)GalNAc in gangliosides GM1 and GD1b: improvement following immunotherapy..  Neurology.  1990 May 1. 40(5):842-4.
[PubMed]

Shy M.  Immunological aspects of motor neuron disease..  Research publications - Association for Research in Nervous and Mental Disease.  1990 January 1. 68:241-56.
[PubMed]

Shy M, Evans V, Lublin F, Knobler R, Heiman-Patterson T, Tahmoush A, Parry G, Schick P, DeRyk T.  Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia..  Annals of neurology.  1989 May 1. 25(5):511-3.
[PubMed]

Latov N, Hays A, Donofrio P, Liao J, Ito H, McGinnis S, Konstadoulakis M, Freddo L, Shy M.  Monoclonal IgM with unique specificity to gangliosides GM1 and GD1b and to lacto-N-tetraose associated with human motor neuron disease..  Neurology.  1988 May 1. 38(5):763-8.
[PubMed]

Zuckerman S, Pesce M, Rowland L, Sherman W, Shy M, Latov N, Osserman E.  An alert for motor neuron diseases and peripheral neuropathy: monoclonal paraproteinemia may be missed by routine electrophoresis..  Archives of neurology.  1987 March 1. 44(3):250-1.
[PubMed]

Freddo L, Hays A, Nickerson K, Spatz L, McGinnis S, Lieberson R, Vedeler C, Shy M, Autilio-Gambetti L, Grauss F.  Monoclonal anti-DNA IgM kappa in neuropathy binds to myelin and to a conformational epitope formed by phosphatidic acid and gangliosides..  Journal of immunology (Baltimore, Md. : 1950).  1986 December 15. 137(12):3821-5.
[PubMed]

Shy M, Rowland L, Smith T, Trojaborg W, Latov N, Sherman W, Pesce M, Lovelace R, Osserman E.  Motor neuron disease and plasma cell dyscrasia..  Neurology.  1986 November 1. 36(11):1429-36.
[PubMed]

Shy M, Gabel C, Vietorisz E, Latov N.  Characterization of oligosaccharides that bind to human anti-MAG antibodies and to the mouse monoclonal antibody HNK-1..  Journal of neuroimmunology.  1986 October 1. 12(4):291-8.
[PubMed]

Shy M, Vietorisz T, Nobile-Orazio E, Latov N.  Specificity of human IgM M-proteins that bind to myelin-associated glycoprotein: peptide mapping, deglycosylation, and competitive binding studies..  Journal of immunology (Baltimore, Md. : 1950).  1984 November 1. 133(5):2509-12.
[PubMed]

Nobile-Orazio E, Hays A, Latov N, Perman G, Golier J, Shy M, Freddo L.  Specificity of mouse and human monoclonal antibodies to myelin-associated glycoprotein..  Neurology.  1984 October 1. 34(10):1336-42.
[PubMed]

Cacace A, Shy M, Satya-Murti S.  Brainstem auditory evoked potentials: a comparison of two high-frequency filter settings..  Neurology.  1980 July 1. 30(7 Pt 1):765-7.
[PubMed]

Date Last Modified: 08/27/2015 - 13:23:08