Associate Professor of Pediatrics
- Endocrinology and Diabetes
Associate Professor of
Biochemistry
Contact Information
Primary Office: 1270B CBRB
Iowa City, IA 52242
Primary Office Phone: 319-335-7383
Email: andrew-norris@uiowa.edu
Web: Norris Laboratory
Education
BS, Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts
MD, Medicine, Washington University School of Medicine, St. Louis, Missouri
PhD, Molecular Biology, Washington University School of Medicine, St. Louis, Missouri
Residency, University of Iowa Hospitals & Clinics, Iowa City, Iowa
Fellowship, Children's Hospital Boston & Joslin Diabetes Center, Boston, Massachusetts
Post Doctoral, Joslin Diabetes Center
Licensure and Certifications
Pediatric Endocrinology
Education/Training Program Affiliations
Biosciences Graduate Program
Department of Biochemistry PhD
Interdisciplinary Graduate Program in Informatics
Research Summary
Our work is currently focused on three questions. (1) How does fetal over- or under-exposure to macronutrients incite poor metabolism? To study this, we have developed an in vivo fetal model accomplished via unilateral infusion of macronutrients into the uterine artery. (2) How does cystic fibrosis cause diabetes? We are working collaboratively with other University of Iowa investigators to better understand the pathophysiology of cystic fibrosis related diabetes. (3) How does direct action on skeletal muscle of the thiazolidinediones and their target, the transcription factor PPARgamma, help treat diabetes? We have recently demonstrated that PPARgamma directly augments the PDK1:AKT nexus of insulin signaling despite increasing muscle lipid uptake.
Center, Program and Institute Affiliations
Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases
Fraternal Order of Eagles Diabetes Research Center
Obesity Initiative
Date Last Modified: 03/28/2013 -
08:30:41