Pathology

Sergei I. Syrbu, MD, PhD

Portrait

Medical Director, Immunopathology Laboratory
Clinical Associate Professor of Pathology  - Anatomic Pathology

Contact Information

Primary Office: 5338B Roy Carver Pavilion
Iowa City, IA 52242
Primary Office Phone: 319-356-7372

Email: sergei-syrbu@uiowa.edu

Education

MD, State University of Medicine, Chishinau, Moldova
PhD, All Union Cardiology Research Center, Moscow, USSR

Graduate Student, All Union Cardiology Research Center
Post Doctoral, University of Connecticut Health Center
Residency, Pathology, University of Iowa Carver College of Medicine
Fellowship, Hematopathology, University of Iowa Carver College of Medicine

Licensure and Certifications

State of Iowa Medical License, Iowa Board of Medicine
Hematology, American Board of Pathology
Anatomic and Clinical Pathology, American Board of Pathology

Research Summary

Interests Include: Cytologic and histomorphologic correlations of bone marrow and lymph node biopsies with immunohistochemistry and flow cytometric analysis in hematopoietic disorders and lymphomas. Development of new monoclonal antibodies and antigen retrieval procedures for immunohistochemical staining of formalin-fixed, paraffin embedded tissues.

Selected Publications

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Missing the target: Characterization of bullous pemphigoid patients who are negative using the BP180 enzyme-linked immunosorbant assay. .  Fairley J, Bream M, Fullenkamp C, Syrbu S, Chen M, Messingham K.  J Am Acad Dermatol.  2013  March; 68 (3) :395-403.
[PubMed]

Elevated serum free light chains are associated with event-free and overall survival in two independent cohorts of patients with diffuse large B-cell lymphoma..  Maurer M, Micallef I, Cerhan J, Katzmann J, Link B, Colgan J, Habermann T, Inwards D, Markovic S, Ansell S, Porrata L, Johnston P, Nowakowski G, Thompson C, Gupta M, Syrbu S, Kurtin P, Macon W, Nikcevich D, Witzig T.  J Clin Oncol.  2011  April (2nd Quarter/Spring); 29 (12) :1620-6.
[PubMed]

Independent diagnostic accuracy of flow cytometry obtained from fine-needle aspirates: a 10-year experience with 451 cases..  Savage E, Vanderheyden A, Bell A, Syrbu S, Jensen C.  American journal of clinical pathology.  2011  February; 135 (2) :304-9.
[PubMed]

CD15 expression in Hodgkin and Reed- Sternberg-like cells in lymph node: Pathologic significance and differential diagnosis. .  Nasr M, Syrbu S.  ASCP Check Sample.  2011; 46 (1) :1-8.

Diffuse Large B-cell Lymphoma, Plasmablastic Variant: Clinical Features and Pathologic Diagnosis. .  Bleile M, Syrbu S.  ASCP Check Sample.  2011; 46 (3) :19-27.

Expression profiling of transcription factors in B- or T-acute lymphoblastic leukemia/lymphoma and burkitt lymphoma: usefulness of PAX5 immunostaining as pan-Pre-B-cell marker..  Nasr M, Rosenthal N, Syrbu S.  Am J Clin Pathol.  2010  January (1st Quarter/Winter); 133 (1) :41-8.
[PubMed]

Epstein-Barr virus mimicking lymphoma on FDG-PET/CT..  Thomas D, Syrbu S, Graham M.  Clin Nucl Med.  2009  December; 34 (12) :891-3.
[PubMed]

The utility of PU.1 as an immunohistochemical marker for histiocytic and dendritic lesions of the skin..  Muirhead D, Stone M, Syrbu S.  Am J Dermatopath.  2009  July (3rd Quarter/Summer); 31 (5) :432-5.
[PubMed]

Expression profiling of transcription factors Pax-5, Oct-1, Oct-2, BOB.1, and PU.1 in Hodgkin's and non-Hodgkin's lymphomas: a comparative study using high throughput tissue microarrays..  McCune R, Syrbu S, Vasef M.  Mod Pathol.  2006  July (3rd Quarter/Summer); 19 (7) :1010-8.
[PubMed]

Date Last Modified: 01/08/2013 - 17:05:00