Pathology

J. Stacey Klutts, MD, PhD

Portrait

Chief, Pathology and Laboratory Medicine - Central Iowa VA Health Care System
Staff Pathologist - Iowa City VA Health Care System
Associate Director, Residency Program
Clinical Associate Professor of Pathology  - Clinical Pathology

Contact Information

Primary Office: BW23 Veterans Affairs Medical Center (113)
601 Highway 6 West
Iowa City, IA 52246
Phone: 319-338-0581

Email: stacey-klutts@uiowa.edu

Education

BS, Chemistry, Missouri State University, Springfield, MO
MD, University of Arkansas for Medical Sciences, Little Rock, AR
PhD, University of Arkansas for Medical Sciences, Little Rock, AR

Residency, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, MO
Fellowship, Washington University School of Medicine, St. Louis, MO

Licensure and Certifications

State of Iowa Medical License, Iowa Board of Medicine
Diplomate, Clinical Pathology, American Board of Pathology

Research Summary

Dr. Klutts' clinical responsibilities include many areas of Clinical Pathology, including Clinical Microbiology, Clinical Chemistry and General Clinical Laboratory Administration. His research interests include many areas, including the development and validation of testing for multi-drug resistant microorganisms, novel technologies for microbial detection in clinical labs, mechanisms of health care information delivery and developing methods for pathology resident physician evaluation.

All Publications

Samar D, Kieler J, Klutts J.  Identification and deletion of Tft1, a predicted glycosyltransferase necessary for cell wall ß-1,3;1,4 glucan synthesis in aspergillus fumigatus.  PLoS One.  2015 February 27. 10(2):e0117336.

Schlichting J, Mengeling M, Makki N, Malhotra A, Halfdanarson T, Klutts J, Levy B, Kaboli P, Charlton M.  Veterans' Continued Participation in an Annual Fecal Immunochemical Test Mailing Program for Colorectal Cancer Screening.  J Am Board Fam Med.  2015. 28(4):494-7.
[PubMed]

Healthcare Associated Infection Consortium .  Strain types and antimicrobial resistance patterns of clostridium difficile isolates from the United States, 2011 to 2013 .  Antimicrobial Agents and Chemotherapy.  2014 July. 58(7):4214-18.

Schlichting J, Mengeling M, Makki N, Malhotra A, Halfdanarson T, Klutts J.  Increasing colorectal cancer screening in an overdue population: Participation and cost impacts of adding telephone calls to a FIT mailing program.  Journal of Community Health.  2014 February 6. 39(2):239-47.
[PubMed]

Charlton M, Mengeling M, Halfdanarson T, Makki N, Malhotra A, Klutts S, Levy B, Kaboli P.  Evaluation of a home-based colorectal cancer screening intervention in a rural state.  Journal of Rural Health.  2013 October 25.  30(3):322-32.
[PubMed]

Kieler J, Duong K, Moye-Rowley W, Klutts J.  Targeted gene deletion in Aspergillus fumigatus using microbial machinery and a recyclable marker.  J Microbiol Methods.  2013 October 23. 95(3):373-8.
[PubMed]

Gailey M, Klutts J, Jensen C.  Fine needle aspiration of histoplasmosis in the era of endoscopic ultrasound (EUS) and endobronchial ultrasound (EBUS).  Can Cytopath.  2013 May 15. 121(9):508-17.
[PubMed]

Baselski V, Klutts J.  Point-Counterpoint: Quantitative cultures of bronchoscopically obtained specimens should be performed for optimal management in patients with ventilator associated pneumonia.  Journal of clinical microbiology.  2013 March. 51(3):740-44.
[PubMed]

VICTORY (Veterans Influence of Clonal Types on Resistance: Year 2011) Investigators .  Escherichia coli sequence type 131 (ST131) subclone H30 as an emergent multidrug-resistant pathogen among US veterans .  Clinical Infectious Diseases.  2013. 57(9):1256-65.

Heiss C, Skowyra M, Liu H, Klutts J, Wang Z, Williams M, Srikanta D, Beverly S, Azadi P, Doering T.  Unusual galactofuranose modification of a capsule polysaccharide in the pathogenic yeast Cryptococcus neoformans.  J. Biol. Chem..  2013. 288:10994-1003.

Paul S, Klutts J, Moye-Rowley W.  Analysis of promoter function in Aspergillus fumigatus.  Eukaryotic cell.  2012 September. 11(9):1167-77.
[PubMed]

Kieler J, Duong K, Klutts J.  Amylases and cell wall synthesis in Aspergillus fumigatus.  Keystone Conference: Fungal Pathogens: From Basic Biology to Drug Discovery. Santa Fe, NM.  2012. 

Klutts J, Robinson-Dunn B.  A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in Diagnosis of Invasive Fungal Infections.  Journal of clinical microbiology.  2011 September. 49(9):S39-S42.

Samar D, Mecklenburg E, Kieler J, Klutts J.  Agrobacterium mediated transformation and splinkerette PCR for the development and characterization of an Aspergillus fumigatus cell wall mutant library.  American Society of Microbiology General Meeting. New Orleans, LA.  2011. 

Duong K, Klutts J.  The Role of Amylases in Aspergillus fumigatus cell wall synthesis.  American Society of Microbiology General Meeting - San Diego, CA.  2010. 

Mecklenburg E, Klutts J.  Utilization of a Novel Transformation and Screening Protocol to Generate an Aspergillus fumigatus Cell Wall Mutant Library.  American Society of Microbiology General Meeting - San Diego, CA.  2010. 

Reilly M, Levery S, Castle S, Klutts J, Doering T.  A novel xylosylphosphotransferase activity discovered in Cryptococcus neoformans.  The Journal of biological chemistry.  2009 December. 284(52):36118-27.
[PubMed]

Klutts J, Ford B, Perez N, Gronowski A.  Evidence-based approach for interpretation of Epstein-Barr virus serological patterns.  Journal of clinical microbiology.  2009 October. 47(10):3204-10.
[PubMed]

Heiss C, Klutts J, Wang Z, Doering T, Azadi P.  The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid.  Carbohydrate research.  2009 May. 344(7):915-20.
[PubMed]

Kieler J, Klutts J.  A Glucosyltransferase in Aspergillus fumigatus with a Potential Role in Cell Wall Synthesis.  American Society of Microbiology General Meeting.  2009. 

Castle S, Owuor E, Thompson S, Garnsey M, Klutts J, Doering T, Levery S.  Beta1,2-xylosyltransferase Cxt1p is solely responsible for xylose incorporation into Cryptococcus neoformans glycosphingolipids.  Eukaryotic cell.  2008 September. 7(9):1611-5.
[PubMed]

Klutts J, Wu A, Smith A, Yen-Lieberman B, Gronowski A.  Diagnostic performance of a new automated heterophile antibody test in adults and children.  Diagnostic microbiology and infectious disease.  2008 July. 61(3):351-3.
[PubMed]

Klutts J, Doering T.  Cryptococcal xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans plays a direct role in the synthesis of capsule polysaccharides.  The Journal of biological chemistry.  2008 May. 283(21):14327-34.
[PubMed]

Kieler J, Klutts J.  A Novel Glucosyltransferase in Aspergillus fumigatus—New Implications for Cell Wall Synthesis.  Interscience Conference on Antimicrobial Agents and Chemotherapy/Infectious Diseases Society of America. Washington, D.C.  2008. 

Klutts J, Levery S, Doering T.  A beta-1,2-xylosyltransferase from Cryptococcus neoformans defines a new family of glycosyltransferases.  The Journal of biological chemistry.  2007 June. 282(24):17890-9.
[PubMed]

Klutts J, Scott M.  Disorders of Water, Electrolyte, and Acid-Base Metabolism.  Elsevier, Philadelphia, PA.  2007. 

Scott M, LeGrys V, Klutts J.  Electrolytes and Blood Gases.  Elsevier, Philadelphia, PA.  2007. 

Klutts J.  Hot, Tired and Lumpy - A Case of Classical EBV-Related Mononucleosis.  John Wiley & Sons, Inc., Hoboken, NJ.  2007. 

Klutts J, Yoneda A, Reilly M, Bose I, Doering T.  Glycosyltransferases and their products: cryptococcal variations on fungal themes.  FEMS yeast research.  2006 June. 6(4):499-512.
[PubMed]

Klutts J, Yoneda A, Reilly M, Bose I, Doering T,  .  Glycosyltransferases and Their Products: Cryptococcal Variations on Fungal Themes.  FEMS Yeast Research.  2006. 6:499-512.

Klutts J, Levery S, Doering T.  Xylosyltransferases and Capsule Biosynthesis in Cryptococcus neoformans.  Academy of Clinical Laboratory Physicians and Scientists (ACLPS) Annual Meeting. Chicago, IL.  2006. 

Klutts J, Levery S, Doering T.  Xylosyltransferases and Capsule Biosynthesis in Cryptococcus neoformans.  American Society for Microbiology, General Meeting. Orlando, FL.  2006. 

Klutts J, Levery S, Doering T.  A Beta-1,2 Xylosyltransferase from Cryptococcus neoformans.  ACLP Annual Meeting, Pittsburg, PA.  2005. 

Klutts J, Levery S, Doering T.  A Beta-1,2 Xylosyltransferase from Cryptococcus neoformans.  American Society for Microbiology General Meeting. Atlanta, GA.  2005. 

Klutts J, Levery S, Doering T.  A Beta-1,2 Xylosyltransferase from Cryptococcus neoformans.  Annual Meeting of the Society for Glycobiology. Boston, MA.  2005. 

Klutts J, Levery S, Doering T.  A Beta-1,2 Xylosyltransferase from Cryptococcus neoformans.  Gordon Conference on Glycobiology. Ventura, VA.  2005. 

Klutts J, Levery S, Doering T.  A Beta-1,2 Xylosyltransferase from Cryptococcus neoformans.  International Meeting of Cryptococcus and Cryptococcosis (ICCC), Biennial Meeting. Boston, MA .  2005. 

Scott M, LeGrys V, Klutts J.  Electrolytes and Blood Gases.  Elsevier, Philadelphia, PA.  2005. 

Klutts J, Scott M.  Physiology and Disorders of Water, Electrolytes, and Acid-Base Metabolism.  Elsevier, Philadelphia, PA.  2005. 

Griffith C, Klutts J, Zhang L, Levery S, Doering T.  UDP-glucose dehydrogenase plays multiple roles in the biology of the pathogenic fungus Cryptococcus neoformans.  The Journal of biological chemistry.  2004 December. 279(49):51669-76.
[PubMed]

Klutts J, Liao R, Dunne W, Gronowski A.  Evaluation of a multiplexed bead assay for assessment of Epstein-Barr virus immunologic status.  Journal of clinical microbiology.  2004 November. 42(11):4996-5000.
[PubMed]

Klutts J, Liao R, Dunne W, Gronowski A.  Evaluation of the Bio-Plex 2200 Multi-Analyte System for Detection of Antibodies to Epstein-Barr Virus.  ACLPS Annual Meeting. Denver, CO.  2004. 

Klutts J, Doering T.  Purification and Characterization of a Xylosyltransferase from Cryptococcus neoformans.  American Society for Microbiology, General Meeting. New Orleans, LA.  2004. 

Klutts J, Dunne W.  Detection of Gram-Positive and Gram-Negative Bacteria in Platelet Products Using an Acridine Orange Staining Technique.  ACLPS Annual Meeting. Tucson, AZ.  2003. 

Klutts J, Eby C.  Evaluation of a Micro-particle Agglutination Assay for the Diagnosis of Heparin-Induced Thrombocytopenia.  ACLPS Annual Meeting. Tucson, AZ.  2003. 

Klutts J, Pastuszak I, Edavana V, Thampi P, Pan Y, Abraham E, Carroll J, Elbein A.  Purification, cloning, expression, and properties of mycobacterial trehalose-phosphate phosphatase.  The Journal of biological chemistry.  2003 January. 278(4):2093-100.
[PubMed]

Klutts J, Hatanaka K, Pan Y, Elbein A.  Biosynthesis of d-arabinose in Mycobacterium smegmatis: specific labeling from d-glucose.  Archives of biochemistry and biophysics.  2002 February. 398(2):229-39.
[PubMed]

Klutts J.  The Biosynthesis of D-Arabinose and D-Trehalose in Mycobacterium smegmatis, PhD Dissertation-University of Arkansas for Medical Sciences.  2002. 

Klutts J, Pan Y, Elbein A.  The Purification and characterization of a Trehalose-phosphate Phosphatase from Mycobacterium smegmatis.  ACLPS Annual Meeting. New York, NY.  2002. 

Date Last Modified: 08/21/2015 - 13:45:18