Pathology

David Meyerholz, DVM, PhD

Portrait

Director, Division of Comparative Pathology
Associate Professor of Pathology

Contact Information

Primary Office: 1165 Medical Laboratories
Iowa City, IA 52242
Primary Office Phone: 319-353-4589

Email: david-meyerholz@uiowa.edu
Web: Division of Comparative Pathology

Education

DVM, Iowa State University
MS, Iowa State University
PhD, Iowa State University

Residency, Veterinary Pathology, Iowa State University

Licensure and Certifications

Diplomate, American College of Veterinary Microbiologists (Virology)
Diplomate, American College of Veterinary Pathologists

Research Summary

Cystic Fibrosis, Lung Diseases and Pathology, Comparative Pathology, Cancer Pathobiology, Pancreatic Diseases

Center, Program and Institute Affiliations

Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases
Center for Immunology and Immune-based Diseases
Institute for Clinical and Translational Science

All Publications

Rasmussen J, Post D, Gibson B, Lindemann S, Apicella M, Meyerholz D, Jones B.  Francisella tularensis Schu S4 LPS Core Sugar and O-antigen Mutants are Attenuated in a Mouse Model of Tularemia.  Infection and immunity [Epub ahead of print].  2014. 
[PubMed]

Sun X, Olivier A, Yi Y, Pope C, Hayden H, Liang B, Sui H, Zhou W, Hager K, Zhang Y, Liu X, Yan Z, Fisher J, Keiser N, Song Y, Tyler S, Goeken J, Kinyon J, Radey M, Fligg D, Wang X, Xie W, Lynch T, Kaminsky P, Brittnacher M, Miller S, Parekh K, Meyerholz D, Hoffman L, Frana T, Stewart Z, Engelhardt J.  Gastrointestinal Pathology in Juvenile and Adult CFTR-Knockout Ferrets.  The American journal of pathology [Epub ahead of print].  2014. 
[PubMed]

Gibson-Corley K, Rogers L, Goeken A, Dupuy A, Meyerholz D.  Keratoacanthoma Pathobiology in Mouse Models.  Diseases.  2014. 2(2):106-119.

Sun X, Olivier A, Liang B, Yi Y, Sui H, Evans T, Zhang Y, Zhou W, Tyler S, Fisher J, Keiser N, Liu X, Yan Z, Song Y, Goeken J, Kinyon J, Fligg D, Wang X, Xie W, Lynch T, Kaminsky P, Stewart Z, Pope R, Frana T, Meyerholz D, Parekh K, Engelhardt J.  Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.  American journal of respiratory cell and molecular biology.  2014. 50(3):502-512.
[PubMed]

Hernandez F, Huang L, Olson M, Powers K, Hernandez L, Meyerholz D, Thedens D, Behlke M, Horswill A, McNamara J.  Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe.  Nature medicine.  2014. 20(3):301-306.
[PubMed]

Dassie J, Hernandez L, Thomas G, Long M, Rockey W, Howell C, Chen Y, Hernandez F, Liu X, Wilson M, Allen L, Vaena D, Meyerholz D, Giangrande P.  Targeted inhibition of prostate cancer metastases with an RNA aptamer to prostate specific membrane antigen (PSMA)..  Molecular therapy [Epub ahead of print].  2014. 
[PubMed]

Adam R, Michalski  A, Bauer C, Abou Alaiwa  M, Gross T, Awadalla  M, Bouzek  D, Gansemer  N, Taft P, Hoegger  M, Diwakar  A, Ochs M, Reinhardt  J, Hoffman E, Beichel  R, Meyerholz D, Stoltz D.  Air trapping and airflow obstruction in newborn cystic fibrosis piglets.  American journal of respiratory and critical care medicine.  2013. 188(12):1434-41.
[PubMed]

Sanders P, Koval O, Jaffer O, Prasad A, Businga T, Scott J, Hayden P, Luczak E, Dickey D, Allamargot C, Olivier A, Meyerholz D, Robison A, Winder D, Blackwell T, Dworski R, Sammut D, Wagner B, Buettner G, Pope R, Miller F, Dibbern M, Haitchi H, Mohler P, Howarth P, Zabner J, Kline J, Grumbach I, Anderson M.  CaMKII Is Essential for the Proasthmatic Effects of Oxidation.  Science translational medicine.  2013. 5(195):195-97.
[PubMed]

Scroggins S, Olivier A, Meyerholz D, Schlueter A.  Characterization of Regulatory Dendritic Cells That Mitigate Acute Graft-versus-Host Disease in Older Mice Following Allogeneic Bone Marrow Transplantation.  PLoS One.  2013. 8(9):e75158.
[PubMed]

Stoltz D, Rokhlina T, Ernst S, Pezzulo A, Ostedgaard L, Karp P, Samuel M, Reznikov L, Rector M, Gansemer N, Bouzek D, Alaiwa M, Hoegger M, Ludwig P, Taft P, Wallen T, Wohlford-Lenane C, McMenimen J, Chen J, Bogen K, Adam R, Hornick E, Nelson G, Hoffman E, Chang E, Zabner J, McCray P, Prather R, Meyerholz D, Welsh M.  Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.  Journal of Clinical Investigation.  2013. 123(6):2685-93.
[PubMed]

Gibson-Corley K, Olivier A, Meyerholz D.  Principles for valid histopathologic scoring in research.  Veterinary pathology.  2013. 50(6):1007-1015.

Simons A, Lu P, Gibson-Corley K, Robinson R, Meyerholz D, Colgan J.  The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation.  Laboratory Investigation.  2013. 93(6):711-719.
[PubMed]

Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I.  The Novel Cytokine Interleukin-33 Activates Acinar Cell Proinflammatory Pathways and Induces Acute Pancreatic Inflammation in Mice.  PLoS One.  2013. 8(2):e56866.
[PubMed]

Rollins K, Meyerholz D, Johnson G, Capparella A, Loew S.  A forensic investigation into the etiology of bat mortality at a wind farm: barotrauma or traumatic injury?.  Veterinary pathology.  2012. 49(2):362-71.
[PubMed]

Olivier A, Yi Y, Sun X, Sui H, Liang B, Hu S, Xie W, Fisher J, Keiser N, Lei D, Zhou W, Yan Z, Li G, Evans T, Meyerholz D, Wang K, Stewart Z, Norris A, Engelhardt J.  Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.  The Journal of clinical investigation.  2012. 122(10):3755-68.
[PubMed]

Capparella A, Loew S, Meyerholz D.  Ecology: Bat deaths from wind turbine blades.  Nature.  2012. 488(7409):32.
[PubMed]

Olivier A, Naumann P, Goeken A, Hochstedler C, Sturm M, Rodgers J, Gibson-Corley K, Meyerholz D.  Genetically modified species in research: Opportunities and challenges for the histology core laboratory.  Journal of histotechnology.  2012. 35(2):63-67.
[PubMed]

Uc A, Giriyappa R, Meyerholz D, Griffin M, Ostedgaard L, Tang X, Abu-El-Haija M, Stoltz D, Ludwig P, Pezzulo A, Abu-El-Haija M, Taft P, Welsh M.  Pancreatic and biliary secretion are both altered in cystic fibrosis pigs .  American journal of physiology. Gastrointestinal and liver physiology.  2012. 303(8):G961-8.
[PubMed]

Abu-El-Haija M, Ramachandran S, Meyerholz D, Abu-El-Haija M, Griffin M, Giriyappa R, Stoltz D, Welsh M, McCray P, Uc A.  Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways.  The American journal of pathology.  2012. 181(2):499-507.
[PubMed]

Chang E, Pezzulo A, Meyerholz D, Potash A, Wallen T, Reznikov L, Sieren J, Karp P, Ernst S, Moninger T, Gansemer N, McCray P, Stoltz D, Welsh M, Zabner J.  Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis.  The Laryngoscope.  2012. 122(9):1898-905.
[PubMed]

Gibson-Corley K, Hochstedler C, Sturm M, Rogers J, Olivier A, Meyerholz D.  Successful Integration of the Histology Core Laboratory in Translational Research.  Journal of histotechnology.  2012. 35(1):17-21.
[PubMed]

Shelton D, Fornalik H, Neff T, Park S, Bender D, DeGeest K, Liu X, Xie W, Meyerholz D, Engelhardt J, Goodheart M.  The role of LEF1 in endometrial gland formation and carcinogenesis.  PloS one.  2012. 7(7):e40312.
[PubMed]

Yu S, Zhou X, Steinke F, Liu C, Chen S, Zagorodna O, Jing X, Yokota Y, Meyerholz D, Mullighan C, Knudson C, Zhao D, Xue H.  The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.  Immunity.  2012. 37(5):813-26.

Curtiss M, Gorman J, Businga T, Traver G, Singh M, Meyerholz D, Kline J, Murphy A, Valenzuela D, Colgan J, Rothman P, Cassel S.  Tim-1 regulates Th2 responses in an airway hypersensitivity model.  European journal of immunology.  2012. 42(3):651-61.
[PubMed]

Klesney-Tait  J, Keck K, Li X, Gilfillan  S, Otero  K, Baruah  S, Meyerholz D, Varga S, Knudson C, Moninger  T, Moreland  J, Zabner J, Colonna M.  Transepithelial migration of neutrophils into the lung requires TREM-1.  Journal of Clinical Investigation.  2012. 123:138-149.
[PubMed]

Bolon B, Altrock B, Barthold S, Baumgarth N, Besselsen D, Boivin G, Boyd K, Brayton C, Cardiff R, Couto S, Eaton K, Foreman O, Griffey S, La Perle K, Lairmore M, Liu C, Meyerholz D, Nikitin A, Schoeb T, Schwahn D, Sellers R, Sundberg J, Tolwani R, Valli V, Zink M.  Advancing translational research.  Science.  2011. 331(6024):1516-7.
[PubMed]

Abu-El-Haija M, Sinkora M, Meyerholz D, Welsh M, McCray P, Butler J, Uc A.  An activated immune and inflammatory response targets the pancreas of newborn pigs with cystic fibrosis.  Pancreatology.  2011. 11(5):506-15.
[PubMed]

Haverkamp J, Charbonneau B, Crist S, Meyerholz D, Cohen M, Snyder P, Svensson R, Henry M, Wang H, Ratliff T.  An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate.  The Prostate.  2011. 71(11):1139-50.
[PubMed]

Berquam-Vrieze K, Nannapaneni K, Brett B, Holmfeldt L, Ma J, Zagorodna O, Jenkins N, Copeland N, Meyerholz D, Knudson C, Mullighan C, Scheetz T, Dupuy A.  Cell of origin strongly influences genetic selection in a mouse model of T-ALL.  Blood.  2011. 118(17):4646-56.
[PubMed]

Ostedgaard L, Meyerholz D, Vermeer D, Karp P, Schneider L, Sigmund C, Welsh M.  Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice.  Proceedings of the National Academy of Sciences of the United States of America.  2011. 108(7):2921-6.
[PubMed]

Lazic T, Sow F, Van Geelen A, Meyerholz D, Gallup J, Ackermann M.  Exposure to ethanol during the last trimester of pregnancy alters the maturation and immunity of the fetal lung.  Alcohol.  2011. 45(7):673-80.
[PubMed]

Weiss K, Christiaansen A, Fulton R, Meyerholz D, Varga S.  Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection.  Journal of immunology.  2011. 187(6):3145-54.
[PubMed]

Bolon B, Altrock B, Barthold S, Baumgarth  N, Besselsen  D, Boivin G, Boyd K, Brayton C, Cardiff R, Couto S, Eaton K, Foreman O, Griffey S, La Perle K, Lairmore M, Liu C, Meyerholz D, Nikitin A, Schoeb T, Schwahn D, Sellers R, Sundberg J, Tolwani R, Valli V, Zink M.  NIH plan will hinder translational studies.  Nature.  2011. 471:7336.

Yuan Z, Meyerholz D, Twait E, Kempuraj D, Williard D, Samuel I.  Systemic inflammation with multiorgan dysfunction is the cause of death in murine ligation-induced acute pancreatitis.  Journal of gastrointestinal surgery.  2011. 15(10):1670-8.
[PubMed]

Kondratowicz A, Lennemann N, Sinn P, Davey R, Hunt C, Moller-Tank S, Meyerholz D, Rennert P, Mullins R, Brindley M, Sandersfeld L, Quinn K, Weller M, McCray P, Chiorini J, Maury W.  T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus.  Proceedings of the National Academy of Sciences of the United States of America.  2011. 108(20):8426-31.
[PubMed]

Muniz V, Barnes J, Paliwal S, Zhang X, Tang X, Chen S, Zamba K, Cullen J, Meyerholz D, Meyers S, Davis J, Grossman S, Henry M, Quelle D.  The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis.  Molecular cancer research.  2011. 9(7):867-77.
[PubMed]

Ostedgaard L, Meyerholz D, Chen J, Pezzulo A, Karp P, Rokhlina T, Ernst S, Hanfland R, Reznikov L, Ludwig P, Rogan M, Davis G, Dohrn C, Wohlford-Lenane C, Taft P, Rector M, Hornick E, Nassar B, Samuel M, Zhang Y, Richter S, Uc A, Shilyansky J, Prather R, McCray P, Zabner J, Welsh M, Stoltz D.  The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.  Science translational medicine.  2011. 3(74):74ra24.
[PubMed]

Samuel I, Yuan Z, Meyerholz D, Twait E, Williard D, Kempuraj D.  A novel model of severe gallstone pancreatitis: murine pancreatic duct ligation results in systemic inflammation and substantial mortality.  Pancreatology.  2010. 10(5):536-44.
[PubMed]

McNamara A, Zamba K, Sokolich J, Jaskille A, Light T, Griffin M, Meyerholz D.  Apoptosis is differentially regulated by burn severity and dermal location.  The Journal of surgical research.  2010. 162(2):258-63.
[PubMed]

O'Keefe B, Giomarelli B, Barnard D, Shenoy S, Chan P, McMahon J, Palmer K, Barnett B, Meyerholz D, Wohlford-Lenane C, McCray P.  Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae.  Journal of virology.  2010. 84(5):2511-21.
[PubMed]

Ulland T, Buchan B, Ketterer M, Fernandes-Alnemri T, Meyerholz D, Apicella M, Alnemri E, Jones B, Nauseef W, Sutterwala F.  Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence.  Journal of immunology.  2010. 185(5):2670-4.
[PubMed]

Stoltz D, Meyerholz D, Pezzulo A, Ramachandran S, Rogan M, Davis G, Hanfland R, Wohlford-Lenane C, Dohrn C, Bartlett J, Nelson G, Chang E, Taft P, Ludwig P, Estin M, Hornick E, Launspach J, Samuel M, Rokhlina T, Karp P, Ostedgaard L, Uc A, Starner T, Horswill A, Brogden K, Prather R, Richter S, Shilyansky J, McCray P, Zabner J, Welsh M.  Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.  Science translational medicine.  2010. 2(29):29ra31.
[PubMed]

Sun X, Sui H, Fisher J, Yan Z, Liu X, Cho H, Joo N, Zhang Y, Zhou W, Yi Y, Kinyon J, Lei-Butters D, Griffin M, Naumann P, Luo M, Ascher J, Wang K, Frana T, Wine J, Meyerholz D, Engelhardt J.  Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.  The Journal of clinical investigation.  2010. 120(9):3149-60.
[PubMed]

Lazic T, Matic M, Gallup J, Van Geelen A, Meyerholz D, Grubor B, Imerman P, de-Macedo M, Ackermann M.  Effects of nicotine on pulmonary surfactant proteins A and D in ovine lung epithelia.  Pediatric pulmonology.  2010. 45(3):255-62.
[PubMed]

Gookin J, Stone M, Yaeger M, Meyerholz D, Moisan P.  Fluorescence in situ hybridization for identification of Tritrichomonas foetus in formalin-fixed and paraffin-embedded histological specimens of intestinal trichomoniasis.  Veterinary parasitology.  2010. 172(2-Jan):139-43.
[PubMed]

Fulton R, Meyerholz D, Varga S.  Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection.  Journal of immunology.  2010. 185(4):2382-92.
[PubMed]

Hunninghake G, Doerschug K, Nymon A, Schmidt G, Meyerholz D, Ashare A.  Insulin-like growth factor-1 levels contribute to the development of bacterial translocation in sepsis.  American journal of respiratory and critical care medicine.  2010. 182(4):517-25.
[PubMed]

Peters A, Stunz L, Meyerholz D, Mohan C, Bishop G.  Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice.  Journal of immunology.  2010. 185(7):4053-62.
[PubMed]

Meyerholz D, Stoltz D, Namati E, Ramachandran  S, Pezzulo  A, Smith  A, Rector M, Suter  M, Kao S, McLennan  G, Tearney  G, Zabner J, McCray, Jr. P, Welsh M.  Loss of CFTR function produces abnormalities in tracheal development in neonatal pigs and young children.  American Journal of Respiratory and Critical Care Medicine.  2010. 182(10):1251-61.
[PubMed]

Langlois R, Meyerholz D, Coleman R, Cook R, Waldschmidt T, Legge K.  Oseltamivir treatment prevents the increased influenza virus disease severity and lethality occurring in chronic ethanol consuming mice.  Alcoholism, clinical and experimental research.  2010. 34(8):1425-31.
[PubMed]

Meyerholz D, Stoltz D, Pezzulo A, Welsh M.  Pathology of gastrointestinal organs in a porcine model of cystic fibrosis.  The American journal of pathology.  2010. 176(3):1377-89.
[PubMed]

Radi Z, Meyerholz D, Ackermann M.  Pulmonary cyclooxygenase-1 (COX-1) and COX-2 cellular expression and distribution after respiratory syncytial virus and parainfluenza virus infection.  Viral immunology.  2010. 23(1):43-8.
[PubMed]

Lu P, Hankel I, Knisz J, Marquardt A, Chiang M, Grosse J, Constien R, Meyer T, Schroeder A, Zeitlmann L, Al-Alem U, Friedman A, Elliott E, Meyerholz D, Waldschmidt T, Rothman P, Colgan J.  The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.  The Journal of experimental medicine.  2010. 207(7):1359-67.
[PubMed]

Meyerholz D, Rodgers J, Castilow E, Varga S.  Alcian Blue and Pyronine Y histochemical stains permit assessment of multiple parameters in pulmonary disease models.  Veterinary pathology.  2009. 46(2):325-8.
[PubMed]

Meyerholz D, Griffin M, Castilow E, Varga S.  Comparison of histochemical methods for murine eosinophil detection in an RSV vaccine-enhanced inflammation model.  Toxicologic pathology.  2009. 37(2):249-55.
[PubMed]

Welsh M, Rogers C, Stoltz D, Meyerholz D, Prather R.  Development of a porcine model of cystic fibrosis.  Transactions of the American Clinical and Climatological Association.  2009. 120:149-62.
[PubMed]

McGill J, Meyerholz D, Edsen-Moore M, Young B, Coleman R, Schlueter A, Waldschmidt T, Cook R, Legge K.  Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections.  Journal of immunology.  2009. 182(12):7803-8.
[PubMed]

Sow F, Gallup J, Meyerholz D, Ackermann M.  Gene profiling studies in the neonatal ovine lung show enhancing effects of VEGF on the immune response.  Developmental and comparative immunology.  2009. 33(6):761-71.
[PubMed]

Murthy S, Adamcakova-Dodd A, Perry S, Tephly L, Keller R, Metwali N, Meyerholz D, Wang Y, Glogauer M, Thorne P, Carter A.  Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis.  American journal of physiology. Lung cellular and molecular physiology.  2009. 297(5):L846-55.
[PubMed]

Meyerholz D, Piester T, Sokolich J, Zamba G, Light T.  Morphological parameters for assessment of burn severity in an acute burn injury rat model.  International journal of experimental pathology.  2009. 90(1):26-33.
[PubMed]

Meyerholz D, Piester T, McNamara A, Sokolich J, Jaskille A, Orion K, Zamba K, Light T.  Pharmacologic modification to resuscitation fluid after thermal injury--is drotrecogin alfa the answer to arrest burn depth progression?.  The Journal of trauma.  2009. 67(5):996-1003.
[PubMed]

Khanolkar A, Hartwig S, Haag B, Meyerholz D, Epping L, Haring J, Varga S, Harty J.  Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome.  Journal of virology.  2009. 83(18):9258-72.
[PubMed]

Wohlford-Lenane C, Meyerholz D, Perlman S, Zhou H, Tran D, Selsted M, McCray P.  Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease.  Journal of virology.  2009. 83(21):11385-90.
[PubMed]

Dassie J, Liu X, Thomas G, Whitaker R, Thiel K, Stockdale K, Meyerholz D, McCaffrey A, McNamara J, Giangrande P.  Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.  Nature biotechnology.  2009. 27(9):839-49.
[PubMed]

Khanolkar A, Hartwig S, Haag B, Meyerholz D, Harty J, Varga S.  Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice.  Journal of virology.  2009. 83(17):8946-56.
[PubMed]

Bouley D, Meyerholz D, Sellers R, Boyd K, La Perle K.  Where's the mouse pathology training?.  Veterinary pathology.  2009. 46(6):1245-7.
[PubMed]

Meyerholz D, Edsen-Moore M, McGill J, Coleman R, Cook R, Legge K.  Chronic alcohol consumption increases the severity of murine influenza virus infections.  Journal of immunology.  2008. 181(1):641-8.
[PubMed]

Castilow E, Olson M, Meyerholz D, Varga S.  Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus.  Journal of virology.  2008. 82(5):2196-207.
[PubMed]

Rogers C, Stoltz D, Meyerholz D, Ostedgaard L, Rokhlina T, Taft P, Rogan M, Pezzulo A, Karp P, Itani O, Kabel A, Wohlford-Lenane C, Davis G, Hanfland R, Smith T, Samuel M, Wax D, Murphy C, Rieke A, Whitworth K, Uc A, Starner T, Brogden K, Shilyansky J, McCray P, Zabner J, Prather R, Welsh M.  Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.  Science.  2008. 321(5897):1837-41.
[PubMed]

Castilow E, Meyerholz D, Varga S.  IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease.  Journal of immunology.  2008. 180(4):2376-84.
[PubMed]

Meyerholz D, Williard D, Grittmann A, Samuel I.  Murine pancreatic duct ligation induces stress kinase activation, acute pancreatitis, and acute lung injury.  American journal of surgery.  2008. 196(5):675-82.
[PubMed]

Meyerholz D, Edsen-Moore M, McGill J, Coleman R, Cook R, Legge K.  Response to Comment on "Chronic alcohol consumption increases the severity of murine influenza virus infections".  Journal of immunology.  2008. 181(9):5813; author reply 5813-4.
[PubMed]

Netland J, Meyerholz D, Moore S, Cassell M, Perlman S.  Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2.  Journal of virology.  2008. 82(15):7264-75.
[PubMed]

George C, Goss K, Meyerholz D, Lamb F, Snyder J.  Surfactant-associated protein A provides critical immunoprotection in neonatal mice.  Infection and immunity.  2008. 76(1):380-90.
[PubMed]

Rogers C, Abraham W, Brogden K, Engelhardt J, Fisher J, McCray P, McLennan G, Meyerholz D, Namati E, Ostedgaard L, Prather R, Sabater J, Stoltz D, Zabner J, Welsh M.  The porcine lung as a potential model for cystic fibrosis.  American journal of physiology. Lung cellular and molecular physiology.  2008. 295(2):L240-63.
[PubMed]

Itoh T, Iwashita S, Cohen M, Meyerholz D, Linn S.  Ddb2 is a haploinsufficient tumor suppressor and controls spontaneous germ cell apoptosis.  Human molecular genetics.  2007. 16(13):1578-86.
[PubMed]

McCray P, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia H, Halabi C, Sigmund C, Meyerholz D, Kirby P, Look D, Perlman S.  Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus.  Journal of virology.  2007. 81(2):813-21.
[PubMed]

Lazic T, Wyatt T, Matic M, Meyerholz D, Grubor B, Gallup J, Kersting K, Imerman P, Almeida-De-Macedo M, Ackermann M.  Maternal alcohol ingestion reduces surfactant protein A expression by preterm fetal lung epithelia.  Alcohol.  2007. 41(5):347-55.
[PubMed]

Meyerholz D, Samuel I.  Morphologic characterization of early ligation-induced acute pancreatitis in rats.  American journal of surgery.  2007. 194(5):652-8.
[PubMed]

Fach S, Meyerholz D, Gallup J, Ackermann M, Lehmkuhl H, Sacco R.  Neonatal ovine pulmonary dendritic cells support bovine respiratory syncytial virus replication with enhanced interleukin (IL)-4 And IL-10 gene transcripts.  Viral immunology.  2007. 20(1):119-30.
[PubMed]

Meyerholz D, Gallup J, Lazic T, de Macedo M, Lehmkuhl H, Ackermann M.  Pretreatment with recombinant human vascular endothelial growth factor reduces virus replication and inflammation in a perinatal lamb model of respiratory syncytial virus infection.  Viral immunology.  2007. 20(1):188-96.
[PubMed]

Dee F, Meyerholz D.  Teaching medical pathology in the twenty-first century: virtual microscopy applications.  Journal of veterinary medical education.  2007. 34(4):431-6.
[PubMed]

Grubor B, Meyerholz D, Ackermann M.  Collectins and cationic antimicrobial peptides of the respiratory epithelia.  Veterinary pathology.  2006. 43(5):595-612.
[PubMed]

Grubor B, Meyerholz D, Ackermann M.  Collectins and Cationic Antimicrobial Peptides of the Respiratory Epithelia.  Veterinary Pathology.  2006. 43:595-612.

Meyerholz D, DeGraaff J, Gallup J, Olivier A, Ackermann M.  Depletion of alveolar glycogen corresponds with immunohistochemical development of CD208 antigen expression in perinatal lamb lung.  The journal of histochemistry and cytochemistry.  2006. 54(11):1247-53.
[PubMed]

Kawashima K, Meyerholz D, Gallup J, Grubor B, Lazic T, Lehmkuhl H, Ackermann M.  Differential expression of ovine innate immune genes by preterm and neonatal lung epithelia infected with respiratory syncytial virus.  Viral immunology.  2006. 19(2):316-23.
[PubMed]

Meyerholz D, Kawashima K, Gallup J, Grubor B, Ackermann M.  Expression of select immune genes (surfactant proteins A and D, sheep beta defensin 1, and toll-like receptor 4) by respiratory epithelia is developmentally regulated in the preterm neonatal lamb.  Developmental and comparative immunology.  2006. 30(11):1060-9.
[PubMed]

Meyerholz D, Grubor B, Lazic T, Gallup J, de Macedo M, McCray P, Ackermann M.  Monocytic/macrophagic pneumonitis after intrabronchial deposition of vascular endothelial growth factor in neonatal lambs.  Veterinary pathology.  2006. 43(5):689-94.
[PubMed]

Grubor B, Meyerholz D, Lazic T, DeMacedo M, Derscheid R, Hostetter J, Gallup J, DeMartini J, Ackermann M.  Regulation of surfactant protein and defensin mRNA expression in cultured ovine type II pneumocytes by all-trans retinoic acid and VEGF.  International journal of experimental pathology.  2006. 87(5):393-403.
[PubMed]

Meyerholz D, Haynes J.  Actinobacillus capsulatus septicemia in a domestic rabbit (Oryctolagus cuniculus).  Journal of veterinary diagnostic investigation.  2005. 17(1):83-5.
[PubMed]

Meyerholz D, Ackermann M.  Antimicrobial peptides and surfactant proteins in ruminant respiratory tract disease.  Veterinary immunology and immunopathology.  2005. 108(2-Jan):91-6.
[PubMed]

Meyerholz D, Ackermann M.  Antimicrobial peptides and surfactant proteins in ruminant respiratory tract infection.  Veterinary Immunology and Immunopathology.  2005. 108:91-96.

Meyerholz D, Vanloubbeeck Y, Hostetter S, Jordan D, Fales-Williams A.  Surveillance of amyloidosis and other diseases at necropsy in captive trumpeter swans (Cygnus buccinator).  Journal of veterinary diagnostic investigation.  2005. 17(3):295-8.
[PubMed]

Meyerholz D, Hostetter S.  Unilateral perinephric pseudocyst secondary to hydronephrosis in a C57BL/6J mouse.  Veterinary pathology.  2005. 42(4):496-8.
[PubMed]

Meyerholz D, Grubor B, Gallup J, Lehmkuhl H, Anderson R, Lazic T, Ackermann M.  Adenovirus-mediated gene therapy enhances parainfluenza virus 3 infection in neonatal lambs.  Journal of clinical microbiology.  2004. 42(10):4780-7.
[PubMed]

Meyerholz D, Caston S, Haynes J.  Congenital fetal rhabdomyoma in a foal.  Veterinary pathology.  2004. 41(5):518-20.
[PubMed]

Meyerholz D, Gallup J, Grubor B, Evans R, Tack B, McCray P, Ackermann M.  Developmental expression and distribution of sheep beta-defensin-2.  Developmental and comparative immunology.  2004. 28(2):171-8.
[PubMed]

Ackermann M, Gallup J, Zabner J, Evans R, Brockus C, Meyerholz D, Grubor B, Brogden K.  Differential expression of sheep beta-defensin-1 and -2 and interleukin 8 during acute Mannheimia haemolytica pneumonia.  Microbial pathogenesis.  2004. 37(1):21-7.
[PubMed]

Grubor B, Gallup J, Meyerholz D, Crouch E, Evans R, Brogden K, Lehmkuhl H, Ackermann M.  Enhanced surfactant protein and defensin mRNA levels and reduced viral replication during parainfluenza virus type 3 pneumonia in neonatal lambs.  Clinical and diagnostic laboratory immunology.  2004. 11(3):599-607.
[PubMed]

Meyerholz D.  Invited book review of the Textbook of Respiratory Disease in Dogs and Cats, by Lesley G. King.  Journal of the American Veterinary Medical Association.  2004. 224:1926-1927.

Meyerholz D, Grubor B, Fach S, Sacco R, Lehmkuhl H, Gallup J, Ackermann M.  Reduced clearance of respiratory syncytial virus infection in a preterm lamb model.  Microbes and infection.  2004. 6(14):1312-9.
[PubMed]

Meyerholz D, Haynes J.  Solitary retinal astrocytoma in a dog.  Veterinary pathology.  2004. 41(2):177-8.
[PubMed]

Meyerholz D, Stabel T.  Comparison of early ileal invasion by Salmonella enterica serovars Choleraesuis and Typhimurium.  Veterinary pathology.  2003. 40(4):371-5.
[PubMed]

Wu M, Carlson S, Meyerholz D.  Cytopathic effects observed upon expression of a repressed collagenase gene present in Salmonella and related pathogens: mimicry of a cytotoxin from multiple antibiotic-resistant Salmonella enterica serotype Typhimurium phagetype DT104.  Microbial pathogenesis.  2002. 33(6):279-87.
[PubMed]

Meyerholz D, Stabel T, Ackermann M, Carlson S, Jones B, Pohlenz J.  Early epithelial invasion by Salmonella enterica serovar Typhimurium DT104 in the swine ileum.  Veterinary pathology.  2002. 39(6):712-20.
[PubMed]

Meyerholz D, Stabel T, Cheville N.  Segmented filamentous bacteria interact with intraepithelial mononuclear cells.  Infection and immunity.  2002. 70(6):3277-80.
[PubMed]

Carlson S, Meyerholz D, Stabel T, Jones B.  Secretion of a putative cytotoxin in multiple antibiotic resistant Salmonella enterica serotype Typhimurium phagetype DT104.  Microbial pathogenesis.  2001. 31(4):201-4.
[PubMed]

Date Last Modified: 06/07/2014 - 21:56:23