Pathology

David Meyerholz, DVM, PhD

Portrait

Director, Division of Comparative Pathology
Associate Professor of Pathology

Contact Information

Primary Office: 1165 Medical Laboratories
Iowa City, IA 52242
Primary Office Phone: 319-353-4589

Email: david-meyerholz@uiowa.edu
Web: Division of Comparative Pathology

Education

DVM, Iowa State University
MS, Iowa State University
PhD, Iowa State University

Residency, Veterinary Pathology, Iowa State University

Licensure and Certifications

Diplomate, American College of Veterinary Microbiologists (Virology)
Diplomate, American College of Veterinary Pathologists

Research Summary

Cystic Fibrosis, Lung Diseases and Pathology, Comparative Pathology, Cancer Pathobiology, Pancreatic Diseases

Center, Program and Institute Affiliations

Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases
Center for Immunology and Immune-based Diseases
Institute for Clinical and Translational Science

Selected Publications

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Hernandez F, Huang L, Olson M, Powers K, Hernandez L, Meyerholz D, Thedens D, Behlke M, Horswill A, McNamara J.  Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe.  Nature medicine.  2014. 20(3):301-306.
[PubMed]

Adam R, Michalski  A, Bauer C, Abou Alaiwa  M, Gross T, Awadalla  M, Bouzek  D, Gansemer  N, Taft P, Hoegger  M, Diwakar  A, Ochs M, Reinhardt  J, Hoffman E, Beichel  R, Meyerholz D, Stoltz D.  Air trapping and airflow obstruction in newborn cystic fibrosis piglets.  American journal of respiratory and critical care medicine.  2013. 188(12):1434-41.
[PubMed]

Sanders P, Koval O, Jaffer O, Prasad A, Businga T, Scott J, Hayden P, Luczak E, Dickey D, Allamargot C, Olivier A, Meyerholz D, Robison A, Winder D, Blackwell T, Dworski R, Sammut D, Wagner B, Buettner G, Pope R, Miller F, Dibbern M, Haitchi H, Mohler P, Howarth P, Zabner J, Kline J, Grumbach I, Anderson M.  CaMKII Is Essential for the Proasthmatic Effects of Oxidation.  Science translational medicine.  2013. 5(195):195-97.
[PubMed]

Stoltz D, Rokhlina T, Ernst S, Pezzulo A, Ostedgaard L, Karp P, Samuel M, Reznikov L, Rector M, Gansemer N, Bouzek D, Alaiwa M, Hoegger M, Ludwig P, Taft P, Wallen T, Wohlford-Lenane C, McMenimen J, Chen J, Bogen K, Adam R, Hornick E, Nelson G, Hoffman E, Chang E, Zabner J, McCray P, Prather R, Meyerholz D, Welsh M.  Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.  Journal of Clinical Investigation.  2013. 123(6):2685-93.
[PubMed]

Klesney-Tait  J, Keck K, Li X, Gilfillan  S, Otero  K, Baruah  S, Meyerholz D, Varga S, Knudson C, Moninger  T, Moreland  J, Zabner J, Colonna M.  Transepithelial migration of neutrophils into the lung requires TREM-1.  Journal of Clinical Investigation.  2012. 123:138-149.
[PubMed]

Ostedgaard L, Meyerholz D, Chen J, Pezzulo A, Karp P, Rokhlina T, Ernst S, Hanfland R, Reznikov L, Ludwig P, Rogan M, Davis G, Dohrn C, Wohlford-Lenane C, Taft P, Rector M, Hornick E, Nassar B, Samuel M, Zhang Y, Richter S, Uc A, Shilyansky J, Prather R, McCray P, Zabner J, Welsh M, Stoltz D.  The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.  Science translational medicine.  2011. 3(74):74ra24.
[PubMed]

Stoltz D, Meyerholz D, Pezzulo A, Ramachandran S, Rogan M, Davis G, Hanfland R, Wohlford-Lenane C, Dohrn C, Bartlett J, Nelson G, Chang E, Taft P, Ludwig P, Estin M, Hornick E, Launspach J, Samuel M, Rokhlina T, Karp P, Ostedgaard L, Uc A, Starner T, Horswill A, Brogden K, Prather R, Richter S, Shilyansky J, McCray P, Zabner J, Welsh M.  Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.  Science translational medicine.  2010. 2(29):29ra31.
[PubMed]

Meyerholz D, Stoltz D, Namati E, Ramachandran  S, Pezzulo  A, Smith  A, Rector M, Suter  M, Kao S, McLennan  G, Tearney  G, Zabner J, McCray, Jr. P, Welsh M.  Loss of CFTR function produces abnormalities in tracheal development in neonatal pigs and young children.  American Journal of Respiratory and Critical Care Medicine.  2010. 182(10):1251-61.
[PubMed]

Meyerholz D, Stoltz D, Pezzulo A, Welsh M.  Pathology of gastrointestinal organs in a porcine model of cystic fibrosis.  The American journal of pathology.  2010. 176(3):1377-89.
[PubMed]

Rogers C, Stoltz D, Meyerholz D, Ostedgaard L, Rokhlina T, Taft P, Rogan M, Pezzulo A, Karp P, Itani O, Kabel A, Wohlford-Lenane C, Davis G, Hanfland R, Smith T, Samuel M, Wax D, Murphy C, Rieke A, Whitworth K, Uc A, Starner T, Brogden K, Shilyansky J, McCray P, Zabner J, Prather R, Welsh M.  Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.  Science.  2008. 321(5897):1837-41.
[PubMed]

Date Last Modified: 06/07/2014 - 21:56:23