Chen Zhao, MD, PhD


Assistant Professor of Pathology

Contact Information

Primary Office: 1163 Medical Laboratories
Iowa City, IA 52242
Primary Office Phone: 319-384-4668



MD, China Medical University, No. 92, Shenyang, P.R.C.
PhD, Keio University School of Medicine, Tokyo, Japan

Graduate Research Assistant, Department of Pathology, Keio University School of Medicine, Tokyo, Japan
Ph.D. Course, Department of Pathology, Keio University School of Medicine, Tokyo, Japan
Postdoctoral Fellow, Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC
Residency, Department of Pathology and Laboratory Medicine, University of Rochester, NY
Fellowship, Hematopathology , Department of Pathology and Laboratory Medicine, University of Pennsylvania, PA

Selected Publications

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Xiu Y, Xu H, Zhao C, Li J, Morita Y, Yao Z, Xing L, Boyce B.  Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation.  The Journal of clinical investigation.  2014. 124(1):297-310.

Kurokawa M, Ito T, Yang C, Zhao C, Macintyre A, Rizzieri D, Rathmell J, Deininger M, Reya T, Kombluth S.  Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.  Proceedings of the National Academy of Sciences .  2013. 110(6):2300-2305.

Venigalla S, Zhao C, Miyamoto H.  Histopathologic features of atypical glands on prostate biopsy: nucleolar size is a predictor of subsequent detection of prostatic adenocarcinoma.  Prostate.  2013. 73(4):376-381.

Zhao C, Venigalla S, Miyamoto H.  Chronic inflammation on initial benign prostate biopsy is a negative predictor of subsequent cancer detection.  Pathology international.  2012. 62(11):774-776.

Zhao C, Xiu Y, Ashton J, Xing L, Morita Y, Jordan C, Boyce B.  Noncanonical NF-κB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions.  Stem cells .  2012. 30(4):709-718.

Fereshteh M, Ito T, Kovacs J, Zhao C, Kwon H, Konuma V, Chen M, Lefkowitz R, Reya T.  β-Arrestin2 mediates the initiation and progression of myeloid leukemia.  Proceedings of the National Academy of Sciences .  2012. 109(31):12532-12537.

Dai S, Wang Y, Jiang G, Zhang P, Dong X, Wei Q, Xu H, Li Q, Zhao C, Wang E.  Kaiso is expressed in lung cancer: its expression and localization is affected by p120ctn.  Lung Cancer.  2010. 67(2):205-215.

Ito T, Kwon H, Zimdahl B, Congdon K, Blum J, Lento W, Zhao C, Lagoo A, Gerrard G, Foroni L, Goldman J, Goh H, Kim S, Kim D, Chuah C, Oehler V, Radich J, Jordan C, Reya T.  Regulation of myeloid leukaemia by the cell-fate determinant Musashi.  Nature.  2010. 466(7307):765-768.

Liu Y, Wang Y, Zhang Y, Miao Y, Zhao Y, Zhang P, Jiang G, Zhang J, Han Y, Lin X, Yang L, Li Q, Zhao C, Wang E.  Abnormal expression of p120-catenin, E-cadherin, and small GTPases is significantly associated with malignant phenotype of human lung cancer.  Lung Cancer.  2009. 63(3):375-382.

Zhao C, Chen A, Jamieson C, Fereshteh M, Abrahamsson A, Blum J, Kwon H, Kim J, Chute J, Rizzieri D, Munchhof M, VanArsdale T, Beachy P, Reya T.  Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.  Nature.  2009. 458(7239):776-779.

Date Last Modified: 07/01/2014 - 11:23:55