Pathology

Bradley Ford, MD, PhD

Portrait

Medical Director. Clinical Microbiology
Clinical Assistant Professor of Pathology  - Clinical Pathology

Contact Information

Primary Office: C606-B General Hospital
Iowa City, IA 52242
Primary Office Phone: 319-356-2990

Email: bradley-ford-1@uiowa.edu

Education

BS, Biology and Society, Cornell University, Ithaca, NY
PhD, Medical Scientist Training Program, Stony Brook University, Stony Brook, NY
MD, Medical Scientist Training Program, Stony Brook School of Medicine, Stony Brook, NY

Residency, Laboratory and Genomic Medicine, Barnes Jewish Hospital, St. Louis, MO
Fellowship, Medical and Public Health Microbiology, Barnes Jewish Hospital, St. Louis, MO
Post Doctoral, Molecular Microbiology, Washington University, St. Louis, MO

Licensure and Certifications

Diplomate in Clinical Pathology American Board of Pathology

Research Summary

Dr. Ford's research focuses on development of new clinical testing methods using a variety of next generation platforms.

All Publications

Westblade L, Shams F, Duong S, Tariq O, Bulbin A, Klirsfeld D, Sakaria S, Ford B, Burnham C, Ginocchio C.  Septic arthritis of a native knee joint due to corynebacterium striatum.  J Clin Microbiol.  2014 February. 

Storm J, Ford B, Streit J.  Myocardial infection due to Fusobacterium necleatum.  Diagn Microbiol Infec Dis.  2013 December. 77(4):373-5.
[PubMed]

Demarco M, Ford B.  Beyond identification: emerging and future uses for MALDI-TOF mass spectrometry in the clinical microbiology laboratory.  Clin Lab Med.  2013 September. 33(3):611-628.

Pence M, Sharon J, Tekippe M, Pakalniskis B, Ford B, Burnham C.  Two cases of Kerstersia gyiorum isolated from sites of chronic infection.  Journal of Clinical Microbiology.  2013 June. 51(6):2001-04.
[PubMed]

Ford B, Burnham C.  Optimization of routine identification of clinically relevant gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the bruker biotyper.  Journal of clinical microbiology.  2013 May. 51(5):1412-20.
[PubMed]

Brosnahan A, Merriman J, Salgado-Pabón W, Ford B, Schlievert P.  Enterococcus faecalis inhibits superantigen toxic shock syndrome toxin-1-induced interleukin-8 from human vaginal epithelial cells through tetramic acids.  PLosONE.  2013 April. 8(4):e61255.

Guiton P, Hannan T, Ford B, Caparon M, Hultgren S.  Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urirnary tract infections.  Infection and immunity.  2013 January. 81(1):329-39.
[PubMed]

Ford B, Verger D, Dodson K, Volkan E, Kostakioti M, Elam J, Pinkner J, Waksman G, Hultgren S.  Structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket.  Journal of bacteriology.  2012 December. 194(23):6390-7.
[PubMed]

Dunne W, Westblade L, Ford B.  Next-generation and whole-genome sequencing in the diagnostic clinical microbiology laboratory.  European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology.  2012 August. 31(8):1719-26.
[PubMed]

Volkan E, Ford B, Pinkner J, Dodson K, Henderson N, Thanassi D, Waksman G, Hultgren S.  Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine.  Proceedings of the National Academy of Sciences of the United States of America.  2012 June. 109(24):9563-8.
[PubMed]

Han Z, Pinkner J, Ford B, Chorell E, Crowley J, Cusumano C, Campbell S, Henderson J, Hultgren S, Janetka J.  Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides.  Journal of medicinal chemistry.  2012 April. 55(8):3945-59.
[PubMed]

Shu Q, Crick S, Pinkner J, Ford B, Hultgren S, Frieden C.  The E. coli CsgB nucleator of curli assembles to β-sheet oligomers that alter the CsgA fibrillization mechanism.  Proceedings of the National Academy of Sciences of the United States of America.  2012 April. 109(17):6502-7.
[PubMed]

Cusumano C, Pinkner J, Han Z, Greene S, Ford B, Crowley J, Henderson J, Janetka J, Hultgren S.  Treatment and prevention of urinary tract infection with orally active FimH inhibitors.  Science translational medicine.  2011 November. 3(109):109.
[PubMed]

Phan G, Remaut H, Wang T, Allen W, Pirker K, Lebedev A, Henderson N, Geibel S, Volkan E, Yan J, Kunze M, Pinkner J, Ford B, Kay C, Li H, Hultgren S, Thanassi D, Waksman G.  Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.  Nature.  2011 June. 474(7349):49-53.
[PubMed]

Ford B, Eby C, Scott M, Coyne D.  Intra-individual variability in serum hepcidin precludes its use as a marker of iron status in hemodialysis patients.  Kidney international.  2010 October. 78(8):769-73.
[PubMed]

Ford B, Han Z, Pinkner J, Obermann R, Nolan W, Wildman S, Hobbs D, Ellenberger T, Cusumano C, Hultgren S, Janetka J.  Structure-based drug design and optimization of mannoside bacterial FimH antagonists.  Journal of medicinal chemistry.  2010 June. 53(12):4779-92.
[PubMed]

Ford B, Rêgo A, Ragan T, Pinkner J, Dodson K, Driscoll P, Hultgren S, Waksman G.  Structural homology between the C-terminal domain of the PapC usher and its plug.  Journal of bacteriology.  2010 April. 192(7):1824-31.
[PubMed]

Ford B, Boykevisch S, Zhao C, Kunzelmann S, Bar-Sagi D, Herrmann C, Nassar N.  Characterization of a Ras mutant with identical GDP- and GTP-bound structures.  Biochemistry.  2009 December. 48(48):11449-57.
[PubMed]

Klutts J, Ford B, Perez N, Gronowski A.  Evidence-based approach for interpretation of Epstein-Barr virus serological patterns.  Journal of clinical microbiology.  2009 October. 47(10):3204-10.
[PubMed]

Ford B, Coyne D, Eby C, Scott M.  Variability of ferritin measurements in chronic kidney disease; implications for iron management.  Kidney international.  2009 January. 75(1):104-10.
[PubMed]

Ferguson A, Ford B, Gronowski A.  Method validation for cerebral spinal fluid human chorionic gonadotropin measurement with the Advia Centaur.  Clinical chemistry.  2008 August. 54(8):1408-9.
[PubMed]

Mikhailik A, Ford B, Keller J, Chen Y, Nassar N, Carpino N.  A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling.  Molecular cell.  2007 August. 27(3):486-97.
[PubMed]

Kleinman H, Ford B, Keller J, Carpino N, Nassar N.  Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.  Acta crystallographica - Section F, Structural biology and crystallization communications.  2006 March. 62(Pt 3):218-20.
[PubMed]

Ford B, Hornak V, Kleinman H, Nassar N.  Structure of a transient intermediate for GTP hydrolysis by ras.  Structure (London, England : 1993).  2006 March. 14(3):427-36.
[PubMed]

Ford B, Skowronek K, Boykevisch S, Bar-Sagi D, Nassar N.  Structure of the G60A mutant of RAS: implications for the dominant negative effect.  The Journal of biological chemistry.  2005 July. 280(27):25697-705.
[PubMed]

Date Last Modified: 06/07/2014 - 21:56:23