Pathology

Gary L. Baumbach, MD

Portrait

Professor of Pathology  - Anatomic Pathology

Contact Information

Primary Office: 5231-C Roy Carver Pavilion
Iowa City, IA 52242
Primary Office Phone: 319-384-9083

Email: g-baumbach@uiowa.edu

Education

BA, Wartburg College, Waverly, IA
MD, University of Iowa, Iowa City, IA

Externship, Pathology, University of Iowa Hospitals & Clinics
Residency, Pathology, University of Iowa Hospitals & Clinics
Residency, Ophthalmology, University of Iowa Hospitals & Clinics
Fellowship, Cardiovascular Research/Neuropathology , University of Iowa Hospitals & Clinics
Fellowship, Neuropathology , University of Iowa Hospitals & Clinics

Licensure and Certifications

State of Iowa Medical License, Iowa Board of Medicine
Neuropathology Special Qualification in Neuropathology, American Board of Pathology
Opthalmology, American Board of Ophthalmology

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Informatics

Research Summary

The long-term objective of studies in our laboratory is to clarify the relationship between morphology and function of blood vessels in the brain, and to understand the influence of structural changes produced by chronic hypertension and aging on function of the vessel wall. To achieve these goals, in vivo and in vitro methods are used to analyze cerebral vascular mechanics, and morphometric methods to quantitate components of the vessel wall. Hypotheses that are currently being tested include: 1) that contraction of smooth muscle in cerebral arterioles is augmented in early hypertension, prior to the development of vascular hypertrophy, and contraction may be affected by structural alterations that develop during prolonged hypertension, 2) that effects of chronic hypertension on smooth muscle contraction may be different with respect to vessel size and brain region, and 3) that effects of aging on structure and function of blood vessels in the brain may be similar, in some respects, to effects of chronic hypertension. In addition to these interests, our laboratory has recently undertaken a new direction with the aim of extending studies of vascular mechanics and structure to the cellular level. Initial efforts have focused on the use of confocal microscopy and computer-assisted image analysis to examine effects of mechanical deformation on focal and near contacts (focal adhesion sites) in vascular smooth muscle in tissue culture. Focal contacts provide anchorage sites essential for the maintenance of tension within the cell, and are involved in regulation of cell morphology, proliferation, migration, differentiation and responsiveness. It is anticipated that these studies will lead to greater understanding of the fundamental mechanisms that are involved in structural changes in the vessel wall as related to increases in mechanical stress that accompany chronic hypertension and aging.

All Publications

Baumbach G, Rodionov R, Dayoub H, Lynch C, Wilson K, Stevens J, Murry D, Kimoto M, Arning E, Bottiglieri T, Cooke J, Baumbach G, Faraci F, Lentz S.  Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia.  Circulation research.  2010 February. 106(3):551-8.
[PubMed]

Grigoryan M, Geisler S, St Louis E, Baumbach G, Davis P.  Cerebral arteriolar thromboembolism in idiopathic hypereosinophilic syndrome.  Archives of neurology.  2009 April. 66(4):528-31.
[PubMed]

Baumbach G.  NOX2 deficiency prevents angiotensin II-induced hypertrophy and inward remodeling in cerebral arterioles.  Faseb J.  2009. 

Wakisaka Y, Miller J, Chu Y, Baumbach G, Wilson S, Faraci F, Sigmund C, Heistad D.  Oxidative stress through activation of NAD(P)H oxidase in hypertensive mice with spontaneous intracranial hemorrhage.  Journal of cerebral blood flow and metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism.  2008 June. 28(6):1175-85.
[PubMed]

Baumbach G, Beyer A, Baumbach G, Halabi C, Modrick M, Lynch C, Gerhold T, Ghoneim S, de Lange W, Keen H, Tsai Y, Maeda N, Sigmund C, Faraci F.  Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling.  Hypertension.  2008 April. 51(4):867-71.
[PubMed]

Halabi C, Beyer A, de Lange W, Keen H, Baumbach G, Faraci F, Sigmund C.  Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension.  Cell metabolism.  2008 March. 7(3):215-26.
[PubMed]

Baumbach G.  Interference with PPAR signaling causes cerebral vascular hypertrophy and remodeling.  Stroke.  2008. 

Baumbach G.  Mechanisms of vascular remodeling.  2008. 

Baumbach G.  Mechanisms of vascular remodeling.  2008. 

Baumbach G.  Role of epidermal growth factor receptor on angiotensin II-induced hypertrophy and remodeling in cerebral arterioles.  Faseb J.  2008. 

Baumbach G.  Deficiency of NOX-2 prevents cerebral vascular hypertrophy induced by hypertension but not nitric oxide inhibition.  Faseb J.  2007. 

Baumbach G, Didion S, Faraci F.  Hypertrophy of cerebral arterioles in mice deficient in expression of the gene for CuZn superoxide dismutase.  Stroke; A Journal of Cerebral Circulation.  2006 July. 37(7):1850-5.
[PubMed]

Iida S, Baumbach G, Lavoie J, Faraci F, Sigmund C, Heistad D.  Spontaneous stroke in a genetic model of hypertension in mice.  Stroke; A Journal of Cerebral Circulation.  2005 June. 36(6):1253-8.
[PubMed]

Didion S, Lynch C, Baumbach G, Faraci F.  Impaired endothelium-dependent responses and enhanced influence of Rho-kinase in cerebral arterioles in type II diabetes.  Stroke; A Journal of Cerebral Circulation.  2005 February. 36(2):342-7.
[PubMed]

Baumbach G, Sigmund C, Faraci F.  Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase.  Circulation research.  2004 October. 95(8):822-9.
[PubMed]

Chillon J, Baumbach G.  Effects of indapamide, a thiazide-like diuretic, on structure of cerebral arterioles in hypertensive rats.  Hypertension.  2004 May. 43(5):1092-7.
[PubMed]

Baumbach G.  An experimental model of spontaneously hypertensive mouse.  Stroke.  2004. 

Baumbach G.  Deficiency of the NADPH subunit, gp91phox, prevents cerebral vascular hypertrophy.  Faseb J.  2004. 

Baumbach G.  Effects of chronic nitric oxide synthase inhibition on cerebral arterioles in Wistar-Kyoto rats.  Hypertension.  2004. 22:1-6.

Baumbach G.  Deficiency of copper-zinc superoxide dismutase promotes cerebral vascular hypertrophy.  Faseb J.  2003. 

Baumbach G, Sigmund C, Faraci F.  Cerebral arteriolar structure in mice overexpressing human renin and angiotensinogen.  Hypertension.  2003 January. 41(1):50-5.
[PubMed]

Baumbach G, Sigmund C, Bottiglieri T, Lentz S.  Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice.  Circulation research.  2002 November. 91(10):931-7.
[PubMed]

Greenlee J, Ghodsi A, Baumbach G, VanGilder J.  Synovial chondromatosis of the cervical spine. Case illustration.  Journal of neurosurgery.  2002 July. 97(1 Suppl):150.
[PubMed]

Baumbach G.  Autoregulation: Arterial and Intracranial pressure.  2002. 

Baumbach G.  Deficiency of endothelial NO synthase promotes cerebra1l vascular hypertrophy.  Faseb J.  2002. 

Baumbach G.  Hyperhomocysteinemia promotes hypertrophy in cerebral arterioles.  Circulation.  2002. 106(Suppl II):216.

Baumbach G.  Superoxide contributes to vascular dysfunction in mice that express human renin and angiotensinogen.  Am J Physiol.  2002. 283:H1589-H1576.

Chillon J, Baumbach G.  Effects of an angiotensin-converting enzyme inhibitor and a beta-blocker on cerebral arteriolar dilatation in hypertensive rats.  Hypertension.  2001 June. 37(6):1388-93.
[PubMed]

Baumbach G.  Effects of angiotensin-converting enzyme inhibitors on cerebral vascular structure in chronic hypertension.  J Hyperten.  2000. 18 Supp.:S7-S11.

Baumbach G.  Methods for examining cerebrovascular disease in experimental models of hypertension.  2000. 

Chillon J, Baumbach G.  Effects of an angiotensin-converting enzyme inhibitor and a beta-blocker on cerebral arterioles in rats.  Hypertension.  1999 March. 33(3):856-61.
[PubMed]

Garell P, Menezes A, Baumbach G, Moore S, Nelson G, Mathews K, Afifi A.  Presentation, management and follow-up of Schilder's disease.  Pediatric neurosurgery.  1998 August. 29(2):86-91.
[PubMed]

Chillon J, Ghoneim S, Baumbach G.  Effects of chronic nitric oxide synthase inhibition on cerebral arterioles in rats.  Hypertension.  1997 November. 30(5):1097-104.
[PubMed]

Baumbach G.  Autoregulation of cerebral blood flow.  San Diego, Academic Press.  1997. 

Baumbach G.  Constrictive remodeling: do concepts of remodeling during chronic hypertension apply to restenosis?.  Kluwer Academic Publishers.  1997. 

Baumbach G.  Effects of angiotensin converting enzyme inhibitor on remodeling of cerebral arterioles.  Faseb J.  1997. 

Baumbach G.  Effects of treatment with an angiotensin converting enzyme inhibitor and a ß-blocker on hypertrophy and remodeling of cerebral arterioles.  J Hypertension.  1997. 15(Suppl 4):S89.

Baumbach G.  Mechanisms involved in the genesis of cerebral vascular damage in hypertension.  Elsevier Science.  1997. 

Mulvany M, Baumbach G, Aalkjaer C, Heagerty A, Korsgaard N, Schiffrin E, Heistad D.  Vascular remodeling.  Hypertension.  1996 September. 28(3):505-6.
[PubMed]

Chillon J, Heistad D, Baumbach G.  Effects of endothelin receptor inhibition on cerebral arterioles in hypertensive rats.  Hypertension.  1996 March. 27(3 Pt 2):794-8.
[PubMed]

Baumbach G.  Effects of increased pulse pressure on cerebral arterioles.  Hypertension.  1996 February. 27(2):159-67.
[PubMed]

Baumbach G.  Effects of increased pulse pressure on endothelium-dependent relaxation.  Faseb J.  1996. 

Baumbach G.  Endothelium-derived factors and hypertrophy of cerebral arterioles.  J Vasc Res.  1996. 33(Supp 2):32.

Heistad D, Armstrong M, Baumbach G, Faraci F.  Sick vessel syndrome. Recovery of atherosclerotic and hypertensive vessels.  Hypertension.  1995 September. 26(3):509-13.
[PubMed]

Heistad D, Baumbach G, Faraci F, Armstrong M.  Sick vessel syndrome: vascular changes in hypertension and atherosclerosis.  Journal of human hypertension.  1995 June. 9(6):449-53.
[PubMed]

Baumbach G.  Effect of endothelin receptor inhibition on structure of cerebral arterioles in stroke-prone spontaneously hypertensive rats.  Hypertension.  1995. 

Baumbach G.  Effects of increased pulse pressure on cerebral arterioles during aging.  Faseb J.  1995. 

Baumbach G.  Effects of nitric oxide inhibition on mechanics of cerebral arterioles in rats.  Faseb J.  1995. 

Baumbach G.  Effects of stretching on focal adhesion sites in vascular smooth muscle.  Faseb J.  1995. 

Baumbach G.  Functional and structural alterations of cerebral arterioles in chronic hypertension induced by nitric oxide synthesis inhibition.  British J Pharmacol.  1995. 114(Supp):127P.

Baumbach G.  Remodeling of cerebral arterioles in Dahl-S hypertensive rats.  Faseb J.  1995. 

Chen Y, Torry R, Baumbach G, Tomanek R.  Proportional arteriolar growth accompanies cardiac hypertrophy induced by volume overload.  The American Journal of Physiology.  1994 December. 267(6 Pt 2):H2132-7.
[PubMed]

Baumbach G, Faraci F, Heistad D.  Effects of local reduction in pressure on endothelium-dependent responses of cerebral arterioles.  Stroke; A Journal of Cerebral Circulation.  1994 July. 25(7):1456-61; discussion 1461-2.
[PubMed]

Hajdu M, Baumbach G.  Mechanics of large and small cerebral arteries in chronic hypertension.  The American Journal of Physiology.  1994 March. 266(3 Pt 2):H1027-33.
[PubMed]

Baumbach G.  Changes in the cerebral circulation in chronic hypertension.  1994. 

Baumbach G.  Effects of angiotensin inhibition on hypertrophy and remodeling of cerebral arterioles.  Faseb J.  1994. 

Baumbach G.  Volume-overload cardiac hypertrophy facilitates proportional coronary arteriolar growth.  Faseb J.  1994. 

Hajdu M, McElmurry R, Heistad D, Baumbach G.  Effects of aging on cerebral vascular responses to serotonin in rats.  The American Journal of Physiology.  1993 June. 264(6 Pt 2):H2136-40.
[PubMed]

Baumbach G, Hajdu M.  Mechanics and composition of cerebral arterioles in renal and spontaneously hypertensive rats.  Hypertension.  1993 June. 21(6 Pt 1):816-26.
[PubMed]

Baumbach G, Ghoneim S.  Vascular remodeling in hypertension.  Scanning microscopy.  1993 March. 7(1):137-42; discussion 143.
[PubMed]

Baumbach G.  Effects of hypertension on cerebral vessels.  Hypertension Research.  1993. 16:225-231.

Baumbach G.  Effects of increased pulse pressure on cerebral arterioles.  Faseb J.  1993. 

Fujii K, Weno B, Baumbach G, Heistad D.  Effect of antihypertensive treatment on focal cerebral infarction.  Hypertension.  1992 June. 19(6 Pt 2):713-6.
[PubMed]

Baumbach G.  Cerebral vascular changes during chronic hypertension: good guys and bad guys.  J Hypertension.  1992. 10 (Suppl):S71-S75.

Baumbach G.  Effects of aging on cerebral vascular responses to serotonin and angiotensin.  1992. 

Baumbach G.  Increases in arterial pulse pressure produce hypertrophy of cerebral arterioles.  Faseb J.  1992. 

Baumbach G.  Increases in arterial pulse pressure: a determinant of cerebral vascular hypertrophy.  Hypertension.  1992. 

Baumbach G.  Is pulse pressure a stimulus for altered vascular structure in chronic hypertension?.  Hypertension.  1991 December. 18(6):728-9.
[PubMed]

Baumbach G, Heistad D.  Adaptive changes in cerebral blood vessels during chronic hypertension.  Journal of Hypertension.  1991 November. 9(11):987-91.
[PubMed]

Hajdu M, Heistad D, Ghoneim S, Baumbach G.  Effects of antihypertensive treatment on composition of cerebral arterioles.  Hypertension.  1991 October. 18(4 Suppl):II15-21.
[PubMed]

Heistad D, Lopez J, Baumbach G.  Hemodynamic determinants of vascular changes in hypertension and atherosclerosis.  Hypertension.  1991 April. 17(4 Suppl):III7-11.
[PubMed]

Hajdu M, Heistad D, Baumbach G.  Effects of antihypertensive therapy on mechanics of cerebral arterioles in rats.  Hypertension.  1991 March. 17(3):308-16.
[PubMed]

Baumbach G, Siems J, Heistad D.  Effects of local reduction in pressure on distensibility and composition of cerebral arterioles.  Circulation research.  1991 February. 68(2):338-51.
[PubMed]

Baumbach G.  Arterial pressure and endothelial-dependent cerebral vasodilatation.  Hypertension.  1991. 

Baumbach G.  Cerebral arterioles in renal hypertension: Implications for stroke.  Stroke.  1991. 

Baumbach G.  Effect of antihypertensive treatment on focal cerebral infarction.  Hypertension.  1991. 

Baumbach G.  Effect of arterial pressure on endothelial-dependent responses of cerebral arterioles.  Faseb J.  1991. 

Baumbach G.  Mechanical properties of large and small cerebral arterioles in chronic hypertension.  Faseb J.  1991. 

Loftus C, Greene G, Detwiler K, Baumbach G, Heistad D.  Studies of collateral perfusion to canine middle cerebral artery territory.  The American journal of Physiology.  1990 August. 259(2 Pt 2):H560-6.
[PubMed]

Faraci F, Baumbach G, Heistad D.  Cerebral circulation: humoral regulation and effects of chronic hypertension.  Journal of the American Society of Nephrology : JASN.  1990 July. 1(1):53-7.
[PubMed]

Hajdu M, Heistad D, Siems J, Baumbach G.  Effects of aging on mechanics and composition of cerebral arterioles in rats.  Circulation research.  1990 June. 66(6):1747-54.
[PubMed]

Norbeck T.  Rising health care costs: telling the truth!.  Connecticut medicine.  1990 March. 54(3):142-6.
[PubMed]

Baumbach G.  Effects of aging on cerebral arterioles.  Stroke.  1990. 

Baumbach G.  Effects of antihypertensive treatment on hypertrophy and remodeling of cerebral arterioles.  Faseb J.  1990. 

Baumbach G.  Effects of treatment of hypertension on cerebral arterioles.  1990. 

Heistad D, Mayhan W, Coyle P, Baumbach G.  Impaired dilatation of cerebral arterioles in chronic hypertension.  Blood vessels.  1990. 27(5-Feb):258-62.
[PubMed]

Baumbach G.  Mechanics and composition of cerebral arterioles in renal hypertension.  Faseb J.  1990. 

Baumbach G.  Pulse pressure: a risk factor for cerebral vascular hypertrophy in hypertension.  Hypertension.  1990. 

Faraci F, Choi J, Baumbach G, Mayhan W, Heistad D.  Microcirculation of the area postrema: Permeability and vascular responses.  Circulation research.  1989 August. 65(2):417-25.
[PubMed]

Baumbach G, Heistad D.  Remodeling of cerebral arterioles in chronic hypertension.  Hypertension.  1989 June. 13(6 Pt 2):968-72.
[PubMed]

Williams J, Baumbach G, Armstrong M, Heistad D.  Hypothesis: vasoconstriction contributes to amaurosis fugax.  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.  1989 February. 9(1):111-6.
[PubMed]

Baumbach G, Siems J, Faraci F, Heistad D.  Mechanics and composition of arterioles in brain stem and cerebrum.  The American Journal of Physiology.  1989 February. 256(2 Pt 2):H493-501.
[PubMed]

Baumbach G.  Digestion techniques for exposure of smooth muscle cells in cerebral arterioles.  EMSA.  1989. 

Baumbach G.  Effect of arterial pressure on cerebral arterioles.  Faseb J.  1989. 

Baumbach G.  Effect of sympathetic nerves on composition and distensibility of cerebral arterioles in rats.  J Physiol (London).  1989. 

Baumbach G.  Effects of aging on endothelium dependent responses of cerebral arterioles.  Faseb J.  1989. 

Baumbach G.  Effects of aging on mechanics of cerebral arterioles.  Faseb J.  1989. 

Baumbach G.  Mechanics of cerebral arterioles in renal hypertension.  Hypertension.  1989. 

Baumbach G.  Myogenic mechanisms in the cerebral circulation.  J Hypertens.  1989. 

Baumbach G.  Remodeling of cerebral arterioles in chronic hypertension.  Stroke.  1989. 

Baumbach G.  Trophic role of sympathetic nerves during hypertension.  Excerpta Medica.  1989. II:279-291.

Baumbach G, Walmsley J, Hart M.  Composition and mechanics of cerebral arterioles in hypertensive rats.  The American Journal of Pathology.  1988 December. 133(3):464-71.
[PubMed]

Baumbach G, Heistad D.  Cerebral circulation in chronic arterial hypertension.  Hypertension.  1988 August. 12(2):89-95.
[PubMed]

Baumbach G.  Cerebral microcirculation.  News in Physiological Sciences.  1988. 

Baumbach G.  Effect of arterial pressure on cerebral vascular mechanics.  Stroke.  1988. 

Baumbach G.  Effect of sympathetic nerves on composition of cerebral arterioles in chronic hypertension.  Faseb J.  1988. 

Baumbach G.  Mechanics and composition of cerebral arterioles in chronic hypertension.  Blood Vessels.  1988. 

Baumbach G.  Mechanics of cerebral arterioles in chronic hypertension.  Halpern, W., Pegram, B. L., Brayden, J., MacKay, K., McLaughlin, M. and Osol, G..  1988. 

Baumbach G.  Microcirculation of area postrema: permeability and vascular responses.  Hypertension.  1988. 

Baumbach G.  Neurohumoral regulation of cerebral microvascular pressure.  Perintalogy Press.  1988. 

Baumbach G.  Remodeling of cerebral arterioles during chronic hypertension.  Hypertension.  1988. 

Baumbach G, Dobrin P, Hart M, Heistad D.  Mechanics of cerebral arterioles in hypertensive rats.  Circulation research.  1988 January. 62(1):56-64.
[PubMed]

Baumbach G.  Effect of chronic hypertension on structure of cerebral arterioles.  Fed Proc.  1987. 

Baumbach G.  Effects of vasodilation on disruption of the blood-brain barrier during acute hypertension.  J Cereb Blood Flow Metab.  1987. 7(Supp 1):S510.

Baumbach G.  Mechanical characteristics of arterioles in cerebrum and brain stem.  Fed Proc.  1987. 

Baumbach G.  Mechanics and morphometrics of cerebral blood vessels in chronic hypertension.  J Cereb Blood Flow Metab.  1987. 7(Supp 1):S602.

Baumbach G.  Mechanics of cerebral and brain stem arterioles.  Stroke.  1987. 

Baumbach G.  Serotonin decreases blood flow to retina in atherosclerotic monkeys: a possible cause of amaurosis fugax.  Stroke.  1987. 

Baumbach G.  Sympathetic nerves increase cerebral vascular hypertrophy and distensibility.  Circulation.  1987. 76(Supp IV):IV-36.

Baumbach G.  Vasodilation and disruption of the blood-brain barrier during acute hypertension.  Can J Neurol Sci.  1987. 

Baumbach G, Mayhan W, Heistad D.  Protection of the blood-brain barrier by hypercapnia during acute hypertension.  The American Journal of Physiology.  1986 August. 251(2 Pt 2):H282-7.
[PubMed]

Baumbach G, Skøtt O.  Renin release from different parts of rat afferent arterioles in vitro.  The American Journal of Physiology.  1986 July. 251(1 Pt 2):F12-6.
[PubMed]

Baumbach G.  Cerebral vascular mechanics in early and established hypertension.  Fed Proc.  1986. 

Baumbach G.  Hypertension and cerebral vascular mechanics.  Stroke.  1986. 

Baumbach G.  Morphometric analysis of cerebral arterioles in chronic hypertension.  J Neuropathol Exp Neurol.  1986. 

Baumbach G.  Protective effects of sympathetic nerves during hypertension.  1986. 

Panther L, Baumbach G, Bigner D, Piegors D, Groothuis D, Heistad D.  Vasoactive drugs produce selective changes in flow to experimental brain tumors.  Annals of neurology.  1985 December. 18(6):712-5.
[PubMed]

Baumbach G, Heistad D.  Heterogeneity of brain blood flow and permeability during acute hypertension.  The American Journal of Physiology.  1985 September. 249(3 Pt 2):H629-37.
[PubMed]

Baumbach G.  Cerebral vascular mechanics in hypertension.  Circulation.  1985. 72(1017).

Baumbach G.  Evidence that cerebral vascular hypertrophy protects the blood-brain barrier in chronic hypertension.  Fed Proc.  1985. 44(1589).

Werber A, Baumbach G, Wagner D, Mark A, Heistad D.  Factors that influence stroke in Dahl salt-sensitive rats.  Hypertension.  1985. 7(1):59-64.
[PubMed]

Baumbach G.  Factors that influence stroke in Dahl salt-sensitive rats.  Hypertension.  1985. 7:59-64.

Baumbach G.  Mechanical properties of cerebral vessels in early chronic hypertension.  Microvasc Res.  1985. 

Baumbach G, Heistad D.  Regional, segmental, and temporal heterogeneity of cerebral vascular autoregulation.  Annals of biomedical engineering.  1985. 13(4-Mar):303-10.
[PubMed]

Baumbach G.  Cerebral vascular responses to hypertension during hypercapnia.  Fed Proc.  1984. 

Baumbach G.  Changes in the cerebral circulation in chronic hypertension.  1984. 

Tamaki K, Sadoshima S, Baumbach G, Iadecola C, Reis D, Heistad D.  Evidence that disruption of the blood-brain barrier precedes reduction in cerebral blood flow in hypertensive encephalopathy.  Hypertension.  1984. 6(2 Pt 2):I75-81.
[PubMed]

Baumbach G.  Evidence that disruption of the blood-brain barrier precedes reduction in cerebral blood flow in hypertensive encephalopathy.  Hypertension.  1984. 6:I-75-I-81.

Baumbach G.  Hypercapnia does not increase susceptibility of the blood-brain barrier to disruption.  J Neuropathol Exp Neurol.  1984. 43:351.

Baumbach G.  Regulation of blood flow in experimental brain tumors.  Stroke.  1984. 

Baumbach G.  Responsiveness of experimental brain tumors to vasoactive stimuli.  Clin Res.  1984. 

Baumbach G.  Role of autonomic innervation in modification of cerebral vascular responses.  Neurotransmitters and the Cerebral Circulation.  1984. 

Baumbach G, Heistad D.  Effects of sympathetic stimulation and changes in arterial pressure on segmental resistance of cerebral vessels in rabbits and cats.  Circulation research.  1983 May. 52(5):527-33.
[PubMed]

Baumbach G.  Autoregulation of regional cerebral blood flow during increases in aortic pressure.  Fed Proc.  1983. 42:307.

Baumbach G.  Factors influencing stroke in dahl salt sensitive rats.  Circulation.  1983. 68(III):383.

Baumbach G.  Regional cerebral blood flow in hypertensive encephalopathy and experimental stroke.  J Cereb Blood Flow Metab.  1983. 1 Supp:S429.

Baumbach G.  Regional differences in disruption of the blood-brain barrier during acute hypertension.  J Neuropathol Exp Neurol.  1983. 42:338.

Baumbach G.  Resistance of large and small cerebral vessels during sympathetic stimulation.  J Cereb Blood Flow Metab.  1983. 1 Supp:S164-S165.

Baumbach G.  Cerebral microvascular pressure during sympathetic stimulation.  Fed Proc.  1982. 41:1610.

Baumbach G.  Effect of sympathetic nerves on segmental resistance of cerebral vessels.  Stroke.  1982. 13:114.

Baumbach G.  Ocular toxicity of methanol: An experimental study.  New York Raven Press.  1980. 

Baumbach G, Cancilla P, Hayreh M, Hayreh S.  Experimental injury of the optic nerve with optic disc swelling.  Laboratory investigation; a journal of technical methods and pathology.  1978 July. 39(1):50-60.
[PubMed]

Martin-Amat G, Tephly T, McMartin K, Makar A, Hayreh M, Hayreh S, Baumbach G, Cancilla P.  Methyl alcohol poisoning II - Development of a model for ocular toxicity in methyl alcohol poisoning using the rhesus monkey.  Archives of Ophthalmology.  1977 October. 95(10):1847-50.
[PubMed]

Hayreh M, Hayreh S, Baumbach G, Cancilla P, Martin-Amat G, Tephly T, McMartin K, Makar A.  Methyl alcohol poisoning III - Ocular toxicity.  Archives of Ophthalmology.  1977 October. 95(10):1851-8.
[PubMed]

Baumbach G, Cancilla P, Martin-Amat G, Tephly T, McMartin K, Makar A, Hayreh M, Hayreh S.  Methyl alcohol poisoning IV - Alterations of the morphological findings of the retina and optic nerve..  Archives of Ophthalmology.  1977 October. 95(10):1859-65.
[PubMed]

Baumbach G.  An investigation of experimental optic nerve injury with an ultrastructural protein tracer.  J Neuropathol Exp Neurol.  1976. 35:332.

Date Last Modified: 06/12/2014 - 07:32:37