Vladimir Badovinac, PhD


Associate Professor of Pathology

Contact Information

Primary Office: 3-550 Bowen Science Building
Iowa City, IA 52242
Phone: 319-384-2930

Web: Dr. Badovinac's Research Laboratory


BS, Molecular Biology and Physiology, University of Belgrade, Yugoslavia
PhD, Immunology, Institute for Biological Research and School of Medicine, University of Belgrade, Yugoslavia

Post Doctorate, University of Iowa, Department of Microbiology

Education/Training Program Affiliations

Biosciences Graduate Program
Department of Pathology Graduate Program
Interdisciplinary Graduate Program in Immunology
Medical Scientist Training Program

Research Summary

Regulation of antigen-specific CD8 T cell memory and homeostasis after infection or vaccination.

Center, Program and Institute Affiliations

Center for Immunology and Immune-based Diseases
Holden Comprehensive Cancer Center

Selected Publications

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Condotta S, Khan S, Rai D, Griffith T, Badovinac V.  Polymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion..  Journal of immunology (Baltimore, Md. : 1950).  2015 July 1. 195(1):116-25.

Khan S, Hemann E, Legge K, Norian L, Badovinac V.  Diet-induced obesity does not impact the generation and maintenance of primary memory CD8 T cells.  Journal of Immunology.  2014. 193(12):5873-82.

Martin M, Condotta S, Harty J, Badovinac V.  Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo.  Journal of immunology.  2012. 188(3):1255-65.

Wirth T, Xue H, Rai D, Sabel J, Bair T, Harty J, Badovinac V.  Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation.  Immunity.  2010. 33(1):128-40.

Rai D, Pham N, Harty J, Badovinac V.  Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts.  Journal of immunology.  2009. 183(12):7672-81.

Harty J, Badovinac V.  Shaping and reshaping CD8+ T-cell memory.  Nature reviews. Immunology.  2008. 8(2):107-19.

Badovinac V, Haring J, Harty J.  Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection.  Immunity.  2007. 26(6):827-41.

Badovinac V, Messingham K, Jabbari A, Haring J, Harty J.  Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.  Nature medicine.  2005. 11(7):748-56.

Badovinac V, Porter B, Harty J.  CD8+ T cell contraction is controlled by early inflammation.  Nature immunology.  2004. 5(8):809-17.

Badovinac V, Porter B, Harty J.  Programmed contraction of CD8(+) T cells after infection.  Nature immunology.  2002. 3(7):619-26.

Date Last Modified: 08/04/2015 - 09:28:35