Pathology

Ryan W. Askeland, MD

Portrait

Director, Breast Pathology - Holden Comprehensive Cancer Center
Director of Post-Sophomore Medical Student Fellowship
Clinical Assistant Professor of Pathology  - Anatomic Pathology

Contact Information

Primary Office: 5216-C Roy Carver Pavilion
Iowa City, IA 52242
Primary Office Phone: 319-353-8986

Email: ryan-askeland@uiowa.edu

Education

BA, University of Northern Iowa
Post-Sophomore Fellow, Pathology, University of Iowa Carver College of Medicine
MD, University of Iowa, Iowa City, IA

Residency, Pathology, University of Iowa Carver College of Medicine
Fellowship, Surgical Pathology, University of Iowa Carver College of Medicine
Fellowship, Cytopathology, University of Iowa Carver College of Medicine

Licensure and Certifications

Cytopathology, American Board of Pathology
Anatomic and Clinical Pathology, American Board of Pathology

Research Summary

Interests: Diagnostic surgical and cytopathology, breast pathology.

Center, Program and Institute Affiliations

Holden Comprehensive Cancer Center

All Publications

Maity B, Stewart A, O'Malley Y, Askeland R, Sugg S, Fisher R.  Regulator of G protein signaling 6 (RGS6) is a novel suppressor of breast tumor initiation and progression.  Carcinogenesis (Epub ahead of print).  2013 April 18. 
[PubMed]

Du W, Fang L, Li M, Yang X, Liang Y, Peng C, Qian W, O'Malley Y, Askeland R, Sugg S, Qian J, Lin J, Jiang Z, Yee A, Sefton M, Deng Z, Shan S, Wang C, Yang B.  MicroRNA miR-24 enhances tumor invasion and metastasis by targeting PTPN9 and PTPRF to promote EGF signaling.  J Cell Sci.  2013 February 15. 126(pt 6):1440-53.
[PubMed]

Teoh-Fitzgerald M, Fitzgerald M, Zhong W, Askeland R, Domann F.  Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis.  Oncogene;  2013. 

Fang L, Du W, Yang W, Rutnam Z, Peng C, Li H, O'Malley Y, Askeland R, Sugg S, Liu M, Mehta T, Deng Z, Yang B.  MiR-93 enhances angiogenesis and metastasis by targeting LATS2.  Cell Cycle.  2012 December. 11(23):4352-65.
[PubMed]

Yang L, Park J, Askeland R, Fajardo L.  Rare extramedullary relapse with granulocytic sarcoma of the breast: Imaging findings and pathology correlation.  J Med Diagn Meth.  2012 May 21. 1(1):103.

Askeland E, Newton M, Bockholt N, Knudson M, Henning J, Wang X, Askeland R, Weady P, Smith G, Eisenbraum M, Fraser J, O'Donnell M, Luo Y.  Anti-IL 10-R1 Monoclonal Antibody with Concomitant Bacillus Calmette-Guerin (BCG) Prevents Metastatic Bladder Cancer in an In Vivo Mouse Model.  American Association of Cancer Research Annual Meeting.  2012 April. 

Muniz V, Zhang X, Reed S, Tompkins V, Smith T, Hagen J, Fitzgerald M, Button A, Smith B, Zamba K, Domann F, Mezhir J, Weydert J, Askeland R, Quelle D.  Parf-1A (Partner of ARF Isoform 1A) Promotes Oxaloplatin Resistance and is a New Prognostic Marker of Survival in Pancreatic Ductal Adenocarcinoma.  American Association of Cancer Research Annual Meeting.  2012 April. 

Mitros J, Jensen C, Askeland R.  Cytology and Pitfalls of Endoscopic Ultrasound Sampling of Ectopic Splenic Tissue.  United States and Canadian Academy of Pathology Annual Meeting.  2012 March. 

Spanheimer P, Askeland R, Karwal M, Weigel R.  Increased TFAP2C Expression is Associated with Pathologic Complete Response Following Neoadjuvant Chemotherapy in Primary Breast Cancer.  Pacific Coast Surgical Association 83rd Annual Meeting.  2012. 

Yang L, Park J, Askeland R, Fajardo L.  Necrotizing Granulomatous Inflammation in an Ipsilateral Axillary Lymph Node in a Patient with Invasive Ductal Carcinoma of the Breast.  Radiology Case Reports.  2012. 7(4):1-3.
[Link]

Gailey M, Robinson R, Jensen C, COHEN M, Askeland R, Dahmoush L.  Further Classification of Epithelial Lesions of the Salivary Gland.  United States and Canadian Academy of Pathology Annual Meeting.  2011 March. 

Maity B, Yang J, Huang J, Askeland R, Bera S, Fisher R.  Regulator of G protein signaling 6 (RGS6) induces apoptosis via a mitochondrial-dependent pathway not involving its GTPase-activating protein activity.  J Biol Chem.  2011 January. 286(2):1409-19.
[PubMed]

Padmanabha L, Gomez-Contreras P, Zhang L, Woodfield G, Askeland R, Weigel R, Lal G.  Extracellular Matrix 1 (ECM1) is Over-Expressed in Anaplastic Thyroid Cancers and Appears to be Regulated by Transcription Factor AP2C (TFAP2C).  American College of Surgeons 95th Annual Clinical Congress.  2009 October. 

Askeland R, McGrane S, Reifert D, Kemp J.  Enhancing transfusion safety with an innovative bar-code-based tracking system.  Healthcare quarterly (Toronto, Ont.).  2009. 12 Spec No Patient:85-9.
[PubMed]

Reifert D, Greene D, Hillberry C, Askeland R, Kemp J.  Further Data Driven Indications Of Enhanced Patient Safety with a Barcode-Based Computerized Tracking System.  AABB Annual Meeting and TXPO.  2008 October. 

Askeland R, McGrane S, Levitt J, Dane S, Greene D, Vandeberg J, Walker K, Porcella A, Herwaldt L, Carmen L, Kemp J.  Improving transfusion safety: implementation of a comprehensive computerized bar code-based tracking system for detecting and preventing errors.  Transfusion.  2008 July. 48(7):1308-17.
[PubMed]

Askeland R, Clamon G, Weydert J.  ERCC1 Protein Expression in Small Cell Carcinoma: An Immunohistochemical Study of 41 Primary and Metastatic Neoplasms.  Pathology Research Day.  2007 October. 

Askeland R, McGrane S, Levitt j, Dane S, Greene D, Vandeberg J, Walker K, Porcella A, Herwaldt L, Carmen L, Kemp J.  Improving Transfusion Safety at an Academic Medical Center: Implementation of a Comprehensive Computerized Barcode-Based Tracking System.  Pathology Research Day.  2006 October. 

Askeland R, Deyoung B.  Urothelial Carcinoma in Patients ≤ 30 Years of Age: A Clinicopathologic Analysis of 8 Cases.  United States and Canadian Academy of Pathology Annual Meeting.  2006 March. 

Askeland R, Bromley C, Vasef M.  Epidermal Growth Factor Receptor (EGFR) Protein, p53, and Cyclin D1 Expression in Colon Carcinoma: Correlation with EGFR Gene Amplification Using a Chromogenic In Situ Hybridization (CISH) Assay.  United States and Canadian Academy of Pathology Annual Meeting.  2005 March. 

Askeland R, Bromley C, Vasef M.  Detection of HER-2/neu gene amplification using chromogenic in situ hybridization and tissue microarray: Correlation with HER-2/neu protein expression using immunohistochemistry.  J Histotechnol.  2005. 28(1):11-14.

Askeland R, Jans M, Vasef M.  Tissue microarrays for screening and quality control in immunohistochemistry: Advantages and disadvantages compared with conventional sausage blocks.  J Histotechnol.  2004. 27(2):95-99.

Askeland R, Vasef M.  Detection of HER-2/neu Gene Amplification Using Chromogenic In Situ Hybridization and Tissue Microarray: Correlation with HER-2/neu Protein Expression Using Immunohistochemistry.  Research Week 2003: Constructing the Future of Medicine / University of Iowa College of Medicine .  2003 April. 

Askeland R, Vasef M.  Detection of HER-2/neu Gene Amplification Using Chromogenic In Situ Hybridization and Tissue Microarray: Correlation with HER-2/neu Protein Expression Using Immunohistochemistry.  United States and Canadian Academy of Pathology Annual Meeting.  2003 March. 

Askeland R, Vasef M.  Detection of HER-2/neu Gene Amplification Using Chromogenic In Situ Hybridization and Tissue Microarray: Correlation with HER-2/neu Protein Expression Using Immunohistochemistry.  United States and Canadian Academy of Pathology Annual Meeting.  2003 March. 

Date Last Modified: 07/31/2013 - 10:51:40