Pathology

Alicia Olivier, DVM, PhD

Portrait

Director, Comparative Pathology Laboratory
Assistant Professor of Pathology

Contact Information

Primary Office: 1163 Medical Laboratories
Iowa City, IA 52242
Primary Office Phone: 319-384-4668

Email: alicia-olivier@uiowa.edu
Web: Comparative Pathology Laboratory

Education

BS, Biochemistry and Molecular Biology, Mississippi State University, Starkville, MS
DVM, College of Veterinary Medicine, Mississipi State University, Starkville, MS
PhD, Veterinary Pathology, Iowa State University, Ames, IA

Residency, Veterinary Pathology, Iowa State University, Ames, IA

Licensure and Certifications

Veterinary Medicine License , Iowa Board of Veterinary Medicine
Diplomate, American College of Veterinary Pathologists

Research Summary

Comparative pathology, Animal models of human disease, Rodent pathology, Cystic fibrosis, Lymphoma, Diabetes, Oxidative Damage, Host-pathogen interaction, Immunohistochemical development, Morphometry.

All Publications

Sun X, Olivier A, Yi Y, Pope C, Hayden H, Liang B, Sui H, Zhou W, Hager K, Zhang Y, Liu X, Yan Z, Fisher J, Keiser N, Song Y, Tyler S, Goeken J, Kinyon J, Radey M, Fligg D, Wang X, Xie W, Lynch T, Kaminsky P, Brittnacher M, Miller S, Parekh K, Meyerholz D, Hoffman L, Frana T, Stewart Z, Engelhardt J.  Gastrointestinal Pathology in Juvenile and Adult CFTR-Knockout Ferrets.  The American journal of pathology [Epub ahead of print].  2014. 
[PubMed]

Cassel S, Janczy J, Bing X, Wilson S, Olivier A, Otero J, Iwakura Y, Shayakhmetov D, Bassuk A, Abu-Amer Y, Brogden K, Burns T, Sutterwala F, Ferguson P.  Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice.  Proceedings of the National Academy of Sciences of the United States of America.  2014. 111(3):1072-1077.
[PubMed]

Cassel S, Janczy J, Bing X, Wilson S, Olivier A, Otero J, Iwakura Y, Shayakhmetov D, Bassuk A, Abu-Amer Y, Brogden K, Burns T, Sutterwala F, Ferguson P.  Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice.  Proceedings of the National Academy of Sciences of the United States of America.  2014. 111(3):1072-1077.
[PubMed]

Sun X, Olivier A, Liang B, Yi Y, Sui H, Evans T, Zhang Y, Zhou W, Tyler S, Fisher J, Keiser N, Liu X, Yan Z, Song Y, Goeken J, Kinyon J, Fligg D, Wang X, Xie W, Lynch T, Kaminsky P, Stewart Z, Pope R, Frana T, Meyerholz D, Parekh K, Engelhardt J.  Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.  American journal of respiratory cell and molecular biology.  2014. 50(3):502-512.
[PubMed]

Coleman M, Olivier A, Jacobus J, Mapuskar K, Mao G, Martin S, Riley D, Gius D, Spitz D.  Superoxide mediates acute liver injury in irradiated mice lacking Sirtuin 3.  Antioxidants and redox signaling.  2014. 20(9):1423-1435.
[PubMed]

Gomez J, Tyra H, McCabe D, Olivier A, Rutkowski D.  Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α.  Biochemical and biophysical research communications.  2014. 443(1):115-119.
[PubMed]

Cyr A, Kulak M, Park J, Bogachek M, Spanheimer P, Woodfield G, White-Baer L, O-Malley Y, Sugg S, Olivier A, Zhang W, Domann F, Weigel R.  TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis.  Oncogene.  2014. 
[PubMed]

Duncan K, Rosean T, Tompkins V, Olivier A, Sompallae R, Zhan F, Tricot G, Acevedo  M, Ponto L, Walsh S, Tygrett L, Berger A, Waldschmidt T, Morse H, Sunderland J, Janz S.  (18)F-FDG-PET/CT imaging in an IL-6- and MYC-driven mouse model of human multiple myeloma affords objective evaluation of plasma cell tumor progression and therapeutic response to the proteasome inhibitor ixazomib.  Blood Cancer Journal.  2013. 3:e165.
[PubMed]

Sanders P, Koval O, Jaffer O, Prasad A, Businga T, Scott J, Hayden P, Luczak E, Dickey D, Allamargot C, Olivier A, Meyerholz D, Robison A, Winder D, Blackwell T, Sworski R, Sammut D, Wagner B, Buettner G, Pope R, Miller F, Dibbern M, Haitchi H, Mohler P, Howarth P, Zabner J, Kline J, Grumbach I, Anderson M.  CaMKII Is Essential for the Proasthmatic Effects of Oxidation.  Science translational medicine.  2013. 5(195):195-97.
[PubMed]

Scroggins S, Olivier A, Meyerholz D, Schlueter A.  Characterization of Regulatory Dendritic Cells That Mitigate Acute Graft-versus-Host Disease in Older Mice Following Allogeneic Bone Marrow Transplantation.  PLoS One.  2013. 8(9):e75158.
[PubMed]

Olivier A, Sui H, Klesney-Tait  J, Brooks L, Skopec  A, Kline J, Sanchez  P, Meyerholz D, Zavazava  N, Iannettoni  M, Engelhardt  J, Parekh  K.  Ferret Lung Transplant: An Orthotopic Model of Obliterative Bronchiolitis.  American Journal of Transplantation.  2013. 13(2):467-73.
[PubMed]

Tompkins V, Han S, Olivier A, Syrbu S, Bair T, Button A, Jacobus L, Wang Z, Lifton S, Raychaudhuri  P, Morse H, Weiner G, Link B, Smith B, Janz S.  Identification of candidate B-lymphoma genes by cross-species gene expression profiling.  PLoS One.  2013. 8(10):e76889.
[PubMed]

Iyer S, He Q, Janczy J, Elliott E, Zhong Z, Olivier A, Sadler J, Knepper-Adrian  V, Han R, Qiao L, Eisenbarth S, Nauseef  W, Cassel  S, Sutterwala  F.  Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.  Immunity.  2013. 39(2):311-23.
[PubMed]

Gibson-Corley K, Olivier A, Meyerholz D.  Principles for valid histopathologic scoring in research.  Veterinary Pathology.  2013. 50(6):1007-1015.
[PubMed]

Olivier A, Yi Y, Sun X, Sui H, Liang B, Hu S, Xie W, Fisher J, Keiser N, Lei D, Zhou W, Yan Z, Li G, Evans T, Meyerholz D, Wang K, Stewart Z, Norris A, Engelhardt J.  Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.  The Journal of clinical investigation.  2012. 122(10):3755-68.
[PubMed]

Joly S, Eisenbarth  S, Olivier A, Knepper-Adrian V, Williams A, Kaplan  D, Cassel S, Flavell R, Sutterwala  F.  Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans.  Journal of Immunology.  2012. 189(10):4713-4717.
[PubMed]

Olivier A, Naumann P, Goeken A, Hochstedler C, Sturm M, Rodgers J, Gibson-Corley K, Meyerholz D.  Genetically modified species in research: Opportunities and challenges for the histology core laboratory.  Journal of histotechnology.  2012. 35(2):63-67.
[PubMed]

Lai I, Dhakal K, Gadupudi G, Li M, Ludewig G, Robertson L, Olivier A.  N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents.  Toxicology.  2012. 302(1):25-33.
[PubMed]

Gibson-Corley K, Hochstedler C, Sturm M, Rogers J, Olivier A, Meyerholz D.  Successful Integration of the Histology Core Laboratory in Translational Research.  Journal of histotechnology.  2012. 35(1):17-21.
[PubMed]

Olivier A, Gallup J, van Geelen A, Ackermann M.  Exogenous administration of vascular endothelial growth factor prior to human respiratory syncytial virus a2 infection reduces pulmonary pathology in neonatal lambs and alters epithelial innate immune responses.  Experimental lung research.  2011. 37(3):131-43.
[PubMed]

Sow F, Gallup J, Olivier A, Krishnan S, Patera A, Suzich J, Ackermann M.  Respiratory syncytial virus is associated with an inflammatory response in lungs and architectural remodeling of lung-draining lymph nodes of newborn lambs.  American journal of physiology. Lung cellular and molecular physiology.  2011. 300(1):L12-24.
[PubMed]

Olivier A, Parkes J, Flaherty H, Kline K, Haynes J.  Idiopathic eosinophilic meningoencephalomyelitis in a Rottweiler dog.  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.  2010. 22(4):646-8.
[PubMed]

Tao R, Coleman M, Pennington J, Ozden O, Park S, Jiang H, Kim H, Flynn C, Hill S, Hayes McDonald W, Olivier A, Spitz D, Gius D.  Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.  Molecular cell.  2010. 40(6):893-904.
[PubMed]

Olivier A, Gallup J, de Macedo M, Varga S, Ackermann M.  Human respiratory syncytial virus A2 strain replicates and induces innate immune responses by respiratory epithelia of neonatal lambs.  International journal of experimental pathology.  2009. 90(4):431-8.
[PubMed]

Meyerholz D, DeGraaff J, Gallup J, Olivier A, Ackermann M.  Depletion of alveolar glycogen corresponds with immunohistochemical development of CD208 antigen expression in perinatal lamb lung.  The journal of histochemistry and cytochemistry.  2006. 54(11):1247-53.
[PubMed]

Date Last Modified: 07/31/2013 - 10:51:40